ko pathway ratio_in_study ratio_in_pop p_value ko04380 Osteoclast differentiation 15/140 134/7206 3.8004306287e-08 ko04621 NOD-like receptor signaling pathway 16/140 157/7206 4.99738095659e-08 ko04668 TNF signaling pathway 14/140 120/7206 6.55309658216e-08 ko05164 Influenza A 16/140 167/7206 1.19482557048e-07 ko05161 Hepatitis B 16/140 173/7206 1.95451352989e-07 ko05168 Herpes simplex infection 16/140 182/7206 3.93222826494e-07 ko05162 Measles 13/140 120/7206 4.75983753188e-07 ko04660 T cell receptor signaling pathway 13/140 124/7206 6.97717568486e-07 ko05167 Kaposi's sarcoma-associated herpesvirus infection 15/140 191/7206 3.86354554478e-06 ko04620 Toll-like receptor signaling pathway 10/140 100/7206 2.16739994632e-05 ko04622 RIG-I-like receptor signaling pathway 8/140 62/7206 2.31898917209e-05 ko00120 Primary bile acid biosynthesis 5/140 20/7206 3.15883764142e-05 ko04210 Apoptosis 13/140 180/7206 4.30792186242e-05 ko04662 B cell receptor signaling pathway 9/140 88/7206 4.73710111911e-05 ko04658 Th1 and Th2 cell differentiation 9/140 96/7206 9.4257955226e-05 ko04064 NF-kappa B signaling pathway 9/140 96/7206 9.4257955226e-05 ko04623 Cytosolic DNA-sensing pathway 6/140 41/7206 0.000124092503906 ko05145 Toxoplasmosis 10/140 126/7206 0.000157071521046 ko04137 Mitophagy - animal 8/140 82/7206 0.000176359577588 ko05166 HTLV-I infection 15/140 292/7206 0.000512920314225 ko05140 Leishmaniasis 7/140 75/7206 0.000593089309976 ko04672 Intestinal immune network for IgA production 5/140 37/7206 0.000681035030174 ko05160 Hepatitis C 10/140 153/7206 0.000749652360243 ko05142 Chagas disease (American trypanosomiasis) 9/140 130/7206 0.000916649687855 ko04659 Th17 cell differentiation 8/140 106/7206 0.00100974885995 ko05131 Shigellosis 7/140 82/7206 0.00101494406673 ko04060 Cytokine-cytokine receptor interaction 11/140 191/7206 0.00117367822808 ko04611 Platelet activation 10/140 163/7206 0.00122056375648 ko04917 Prolactin signaling pathway 7/140 87/7206 0.00143949047646 ko05133 Pertussis 7/140 87/7206 0.00143949047646 ko05169 Epstein-Barr virus infection 11/140 206/7206 0.00215130171496 ko04217 Necroptosis 10/140 178/7206 0.00235702080799 ko04624 Toll and Imd signaling pathway 5/140 49/7206 0.00247278748109 ko05340 Primary immunodeficiency 4/140 30/7206 0.0025260979852 ko04612 Antigen processing and presentation 6/140 77/7206 0.00369588790877 ko04630 Jak-STAT signaling pathway 8/140 132/7206 0.00404518472323 ko05321 Inflammatory bowel disease (IBD) 5/140 56/7206 0.00444515996159 ko05150 Staphylococcus aureus infection 4/140 36/7206 0.00496298544564 ko04931 Insulin resistance 8/140 137/7206 0.00506413376312 ko04657 IL-17 signaling pathway 6/140 87/7206 0.00672427145157 ko04218 Cellular senescence 9/140 177/7206 0.00739072712799 ko05152 Tuberculosis 9/140 187/7206 0.0104190779731 ko05330 Allograft rejection 3/140 24/7206 0.0107758776191 ko04650 Natural killer cell mediated cytotoxicity 6/140 97/7206 0.0112461437681 ko05132 Salmonella infection 6/140 98/7206 0.0117932918976 ko04933 AGE-RAGE signaling pathway in diabetic complications 7/140 135/7206 0.0158402863666 ko04062 Chemokine signaling pathway 9/140 201/7206 0.0161231915274 ko05320 Autoimmune thyroid disease 3/140 29/7206 0.0181325101288 ko00966 Glucosinolate biosynthesis 1/140 1/7206 0.0194282542326 ko05215 Prostate cancer 6/140 111/7206 0.020702495019 ko05323 Rheumatoid arthritis 5/140 89/7206 0.0291296306552 ko04920 Adipocytokine signaling pathway 5/140 89/7206 0.0291296306552 ko04666 Fc gamma R-mediated phagocytosis 6/140 122/7206 0.0311430533897 ko05120 Epithelial cell signaling in Helicobacter pylori infection 5/140 92/7206 0.0329745432661 ko04010 MAPK signaling pathway 12/140 321/7206 0.0341038085184 ko05332 Graft-versus-host disease 2/140 18/7206 0.0467983147991