ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	138/845	423/7206	2.4261451275e-32
ko04724	Glutamatergic synapse	68/845	152/7206	4.79177346211e-25
ko05033	Nicotine addiction	39/845	56/7206	3.08080398964e-24
ko05032	Morphine addiction	49/845	110/7206	3.0876543656e-18
ko04728	Dopaminergic synapse	66/845	185/7206	6.02379371475e-18
ko04721	Synaptic vesicle cycle	39/845	80/7206	2.02193512274e-16
ko04727	GABAergic synapse	46/845	110/7206	6.86376417519e-16
ko04713	Circadian entrainment	52/845	136/7206	7.95609468958e-16
ko04723	Retrograde endocannabinoid signaling	59/845	175/7206	7.27359010975e-15
ko04020	Calcium signaling pathway	74/845	265/7206	2.78970543876e-13
ko04726	Serotonergic synapse	48/845	137/7206	5.07554177703e-13
ko04024	cAMP signaling pathway	75/845	279/7206	1.39085085724e-12
ko04725	Cholinergic synapse	52/845	160/7206	1.58154695629e-12
ko04911	Insulin secretion	42/845	117/7206	5.99631041751e-12
ko04744	Phototransduction	19/845	36/7206	2.07989664715e-09
ko04921	Oxytocin signaling pathway	55/845	209/7206	4.45711123263e-09
ko04720	Long-term potentiation	33/845	99/7206	9.94472268806e-09
ko05031	Amphetamine addiction	30/845	91/7206	6.22187221811e-08
ko04070	Phosphatidylinositol signaling system	34/845	112/7206	8.33022572409e-08
ko03040	Spliceosome	1/845	145/7206	3.53069235203e-07
ko04261	Adrenergic signaling in cardiomyocytes	50/845	205/7206	3.79388373757e-07
ko04742	Taste transduction	22/845	61/7206	6.31544245022e-07
ko03010	Ribosome	1/845	129/7206	2.72717695517e-06
ko04730	Long-term depression	24/845	78/7206	5.16512316759e-06
ko05322	Systemic lupus erythematosus	3/845	151/7206	1.63821427589e-05
ko05030	Cocaine addiction	22/845	73/7206	1.83635405415e-05
ko04925	Aldosterone synthesis and secretion	28/845	105/7206	2.02981548918e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	22/845	74/7206	2.32945895092e-05
ko04970	Salivary secretion	26/845	95/7206	2.88167271481e-05
ko05203	Viral carcinogenesis	13/845	277/7206	5.55090266531e-05
ko04360	Axon guidance	48/845	233/7206	7.11410115516e-05
ko03013	RNA transport	5/845	166/7206	7.66651094209e-05
ko04514	Cell adhesion molecules (CAMs)	31/845	130/7206	8.52939119238e-05
ko04022	cGMP-PKG signaling pathway	45/845	216/7206	9.27638278676e-05
ko04072	Phospholipase D signaling pathway	42/845	197/7206	0.000106566230369
ko04010	MAPK signaling pathway	61/845	321/7206	0.00011808541787
ko04971	Gastric acid secretion	25/845	98/7206	0.000176538583754
ko04745	Phototransduction - fly	13/845	38/7206	0.000235673739688
ko05168	Herpes simplex infection	7/845	182/7206	0.000255757823077
ko04060	Cytokine-cytokine receptor interaction	8/845	191/7206	0.000363955989202
ko04120	Ubiquitin mediated proteolysis	4/845	138/7206	0.000404015825325
ko04972	Pancreatic secretion	26/845	111/7206	0.000475024593189
ko04750	Inflammatory mediator regulation of TRP channels	27/845	122/7206	0.000925271699797
ko05164	Influenza A	7/845	167/7206	0.000928142643073
ko04621	NOD-like receptor signaling pathway	6/845	157/7206	0.000942709690896
ko04612	Antigen processing and presentation	1/845	77/7206	0.00113847997562
ko03008	Ribosome biogenesis in eukaryotes	1/845	79/7206	0.00116947158428
ko00562	Inositol phosphate metabolism	21/845	89/7206	0.00136029168749
ko05140	Leishmaniasis	1/845	75/7206	0.00170950061248
ko04960	Aldosterone-regulated sodium reabsorption	12/845	41/7206	0.00194259292017
ko04966	Collecting duct acid secretion	9/845	26/7206	0.00196630295563
ko04014	Ras signaling pathway	50/845	279/7206	0.00223115541924
ko04260	Cardiac muscle contraction	22/845	98/7206	0.00227206461489
ko04141	Protein processing in endoplasmic reticulum	9/845	184/7206	0.0023051436096
ko04740	Olfactory transduction	19/845	80/7206	0.00234457980705
ko04626	Plant-pathogen interaction	7/845	18/7206	0.00294438623512
ko04710	Circadian rhythm	12/845	43/7206	0.00302541274404
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/845	14/7206	0.00333577249566
ko04930	Type II diabetes mellitus	14/845	54/7206	0.00415644368968
ko05161	Hepatitis B	9/845	173/7206	0.00550197795204
ko04630	Jak-STAT signaling pathway	6/845	132/7206	0.00608343293115
ko05166	HTLV-I infection	20/845	292/7206	0.00685125454175
ko05110	Vibrio cholerae infection	15/845	63/7206	0.00873058595719
ko05200	Pathways in cancer	40/845	492/7206	0.00887924337476
ko04071	Sphingolipid signaling pathway	30/845	162/7206	0.00932048820919
ko05133	Pertussis	3/845	87/7206	0.0111134422441
ko05169	Epstein-Barr virus infection	13/845	206/7206	0.0113118243493
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/845	79/7206	0.0122918581634
ko04711	Circadian rhythm - fly	5/845	13/7206	0.0125774581698
ko04964	Proximal tubule bicarbonate reclamation	8/845	29/7206	0.0156310096973
ko04658	Th1 and Th2 cell differentiation	4/845	96/7206	0.0159199820087
ko04064	NF-kappa B signaling pathway	4/845	96/7206	0.0159199820087
ko00280	Valine, leucine and isoleucine degradation	1/845	54/7206	0.017688930177
ko04540	Gap junction	24/845	128/7206	0.0177846579589
ko04110	Cell cycle	8/845	145/7206	0.0180006400538
ko05162	Measles	6/845	120/7206	0.0207857764021
ko04610	Complement and coagulation cascades	3/845	79/7206	0.0218018409104
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/845	59/7206	0.0227087908498
ko04973	Carbohydrate digestion and absorption	10/845	42/7206	0.0259349342544
ko00590	Arachidonic acid metabolism	1/845	52/7206	0.027023252263
ko04924	Renin secretion	17/845	86/7206	0.0271406015738
ko04146	Peroxisome	4/845	89/7206	0.0301065780092
ko05016	Huntington's disease	15/845	215/7206	0.0305373689138
ko05130	Pathogenic Escherichia coli infection	3/845	77/7206	0.0307499810824
ko05214	Glioma	16/845	79/7206	0.0322315586152
ko04722	Neurotrophin signaling pathway	28/845	160/7206	0.0334281284986
ko04012	ErbB signaling pathway	20/845	109/7206	0.0356550050194
ko00620	Pyruvate metabolism	1/845	46/7206	0.0377628357579
ko03420	Nucleotide excision repair	1/845	46/7206	0.0377628357579
ko04657	IL-17 signaling pathway	4/845	87/7206	0.0419509322226
ko00310	Lysine degradation	3/845	73/7206	0.0424979116061