ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 32/296 191/7206 5.7368135851e-12 ko05340 Primary immunodeficiency 13/296 30/7206 4.66737264823e-11 ko04650 Natural killer cell mediated cytotoxicity 19/296 97/7206 9.80544715944e-09 ko04380 Osteoclast differentiation 22/296 134/7206 2.02259671372e-08 ko05321 Inflammatory bowel disease (IBD) 14/296 56/7206 3.50520454221e-08 ko05140 Leishmaniasis 16/296 75/7206 4.179302417e-08 ko04612 Antigen processing and presentation 16/296 77/7206 6.20199566352e-08 ko04621 NOD-like receptor signaling pathway 23/296 157/7206 8.6441828157e-08 ko05150 Staphylococcus aureus infection 11/296 36/7206 1.11972310931e-07 ko05145 Toxoplasmosis 20/296 126/7206 1.6195811265e-07 ko04659 Th17 cell differentiation 18/296 106/7206 2.41077802024e-07 ko05152 Tuberculosis 24/296 187/7206 5.67090498938e-07 ko05330 Allograft rejection 8/296 24/7206 3.05237717759e-06 ko04610 Complement and coagulation cascades 14/296 79/7206 3.19660800897e-06 ko05164 Influenza A 21/296 167/7206 4.11868318564e-06 ko05168 Herpes simplex infection 22/296 182/7206 4.67688449001e-06 ko05162 Measles 17/296 120/7206 6.99204191983e-06 ko04658 Th1 and Th2 cell differentiation 15/296 96/7206 7.23519691445e-06 ko05320 Autoimmune thyroid disease 8/296 29/7206 1.48810639647e-05 ko04137 Mitophagy - animal 13/296 82/7206 2.52918915867e-05 ko04630 Jak-STAT signaling pathway 17/296 132/7206 2.53017039296e-05 ko04064 NF-kappa B signaling pathway 14/296 96/7206 3.27312399001e-05 ko04660 T cell receptor signaling pathway 16/296 124/7206 4.28170837926e-05 ko04640 Hematopoietic cell lineage 11/296 64/7206 4.95334035555e-05 ko04620 Toll-like receptor signaling pathway 14/296 100/7206 5.21178969947e-05 ko05332 Graft-versus-host disease 6/296 18/7206 5.57919904212e-05 ko05144 Malaria 9/296 45/7206 7.08134728688e-05 ko04672 Intestinal immune network for IgA production 8/296 37/7206 0.000100459813257 ko04145 Phagosome 18/296 162/7206 0.000106956394605 ko04217 Necroptosis 19/296 178/7206 0.000118597894566 ko04062 Chemokine signaling pathway 20/296 201/7206 0.000207079944157 ko05167 Kaposi's sarcoma-associated herpesvirus infection 19/296 191/7206 0.00029900035519 ko03050 Proteasome 9/296 54/7206 0.0003070628986 ko05310 Asthma 5/296 17/7206 0.000465338366451 ko00590 Arachidonic acid metabolism 8/296 52/7206 0.00114641314719 ko05416 Viral myocarditis 8/296 55/7206 0.00166727695019 ko04940 Type I diabetes mellitus 6/296 32/7206 0.0016757862283 ko05016 Huntington's disease 1/296 215/7206 0.00239686314703 ko04514 Cell adhesion molecules (CAMs) 13/296 130/7206 0.00253584926145 ko05133 Pertussis 10/296 87/7206 0.00284936516481 ko04622 RIG-I-like receptor signaling pathway 8/296 62/7206 0.00361265804887 ko04623 Cytosolic DNA-sensing pathway 6/296 41/7206 0.0061024200703 ko00480 Glutathione metabolism 7/296 55/7206 0.00686452174991 ko04310 Wnt signaling pathway 1/296 181/7206 0.0071480958485 ko04611 Platelet activation 14/296 163/7206 0.00798415579037 ko00120 Primary bile acid biosynthesis 4/296 20/7206 0.0080244324465 ko04662 B cell receptor signaling pathway 9/296 88/7206 0.00977104655998 ko04910 Insulin signaling pathway 1/296 172/7206 0.0103842681569 ko05224 Breast cancer 1/296 174/7206 0.0104890738844 ko05323 Rheumatoid arthritis 9/296 89/7206 0.0104911810812 ko04670 Leukocyte transendothelial migration 13/296 151/7206 0.0106753416957 ko04664 Fc epsilon RI signaling pathway 8/296 77/7206 0.0132553936289 ko04668 TNF signaling pathway 11/296 120/7206 0.0163386084502 ko04666 Fc gamma R-mediated phagocytosis 11/296 122/7206 0.0170897208181 ko05161 Hepatitis B 14/296 173/7206 0.0171005454585 ko05010 Alzheimer's disease 2/296 202/7206 0.0178772136875 ko04390 Hippo signaling pathway 2/296 188/7206 0.0249275687225 ko00051 Fructose and mannose metabolism 5/296 42/7206 0.027727676089 ko05418 Fluid shear stress and atherosclerosis 13/296 173/7206 0.0310301908564 ko03040 Spliceosome 1/296 145/7206 0.031630413463 ko04110 Cell cycle 1/296 145/7206 0.031630413463 ko05202 Transcriptional misregulation in cancer 14/296 188/7206 0.0370125950451 ko00966 Glucosinolate biosynthesis 1/296 1/7206 0.0410768803776 ko04915 Estrogen signaling pathway 1/296 131/7206 0.0448078803098 ko04713 Circadian entrainment 1/296 136/7206 0.0457203320942 ko04931 Insulin resistance 1/296 137/7206 0.0461088767126