ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04610	Complement and coagulation cascades	38/408	79/7206	4.68538280284e-27
ko04974	Protein digestion and absorption	26/408	96/7206	8.99249681313e-12
ko04975	Fat digestion and absorption	16/408	35/7206	1.2572377113e-11
ko00260	Glycine, serine and threonine metabolism	18/408	48/7206	3.74998480727e-11
ko04978	Mineral absorption	15/408	40/7206	1.66650949903e-09
ko04977	Vitamin digestion and absorption	11/408	22/7206	6.72530868311e-09
ko01200	Carbon metabolism	24/408	128/7206	1.53075981725e-07
ko04976	Bile secretion	18/408	80/7206	3.37769645347e-07
ko05150	Staphylococcus aureus infection	11/408	36/7206	2.77937775657e-06
ko00983	Drug metabolism - other enzymes	11/408	42/7206	1.45397133197e-05
ko01230	Biosynthesis of amino acids	16/408	85/7206	1.76749994177e-05
ko04950	Maturity onset diabetes of the young	9/408	29/7206	1.9871253449e-05
ko03320	PPAR signaling pathway	14/408	69/7206	2.45210798774e-05
ko04614	Renin-angiotensin system	7/408	18/7206	3.26946946138e-05
ko04360	Axon guidance	1/408	233/7206	3.32519187992e-05
ko00980	Metabolism of xenobiotics by cytochrome P450	10/408	40/7206	5.5420712185e-05
ko04973	Carbohydrate digestion and absorption	10/408	42/7206	8.68769316506e-05
ko00100	Steroid biosynthesis	7/408	21/7206	0.00010297077855
ko05034	Alcoholism	2/408	238/7206	0.000161141324491
ko00630	Glyoxylate and dicarboxylate metabolism	9/408	38/7206	0.000205117048163
ko00010	Glycolysis / Gluconeogenesis	13/408	74/7206	0.000224199114161
ko00270	Cysteine and methionine metabolism	10/408	47/7206	0.000237019738901
ko05204	Chemical carcinogenesis	10/408	48/7206	0.000284554071071
ko00030	Pentose phosphate pathway	8/408	32/7206	0.000311104302713
ko05166	HTLV-I infection	4/408	292/7206	0.000383494396853
ko04144	Endocytosis	6/408	342/7206	0.000440738490192
ko00040	Pentose and glucuronate interconversions	7/408	26/7206	0.000455131229664
ko04310	Wnt signaling pathway	1/408	181/7206	0.000485354599528
ko00330	Arginine and proline metabolism	11/408	61/7206	0.000536360580623
ko04216	Ferroptosis	9/408	44/7206	0.000659296921482
ko04723	Retrograde endocannabinoid signaling	1/408	175/7206	0.000716677460468
ko04964	Proximal tubule bicarbonate reclamation	7/408	29/7206	0.000931766476359
ko03013	RNA transport	1/408	166/7206	0.00104126631582
ko05169	Epstein-Barr virus infection	2/408	206/7206	0.00104589208469
ko00591	Linoleic acid metabolism	6/408	22/7206	0.00108959586703
ko00053	Ascorbate and aldarate metabolism	6/408	22/7206	0.00108959586703
ko04010	MAPK signaling pathway	6/408	321/7206	0.00116180521636
ko05200	Pathways in cancer	13/408	492/7206	0.00160487435339
ko00380	Tryptophan metabolism	9/408	50/7206	0.00172397892783
ko04390	Hippo signaling pathway	2/408	188/7206	0.00208667753433
ko00590	Arachidonic acid metabolism	9/408	52/7206	0.00229028533675
ko00680	Methane metabolism	7/408	34/7206	0.00251367428361
ko04141	Protein processing in endoplasmic reticulum	2/408	184/7206	0.00305487026853
ko04110	Cell cycle	1/408	145/7206	0.00324940081796
ko00480	Glutathione metabolism	9/408	55/7206	0.00340690507345
ko00620	Pyruvate metabolism	8/408	46/7206	0.0038499557141
ko04146	Peroxisome	12/408	89/7206	0.0041470713268
ko04920	Adipocytokine signaling pathway	12/408	89/7206	0.0041470713268
ko04217	Necroptosis	2/408	178/7206	0.00442961635881
ko04062	Chemokine signaling pathway	3/408	201/7206	0.00492085393075
ko04972	Pancreatic secretion	14/408	111/7206	0.00526890999105
ko00140	Steroid hormone biosynthesis	7/408	41/7206	0.00746929251055
ko00561	Glycerolipid metabolism	9/408	63/7206	0.00851390315021
ko00830	Retinol metabolism	7/408	42/7206	0.0085386139707
ko04728	Dopaminergic synapse	3/408	185/7206	0.0096041764038
ko04660	T cell receptor signaling pathway	1/408	124/7206	0.0100041783629
ko00340	Histidine metabolism	5/408	25/7206	0.0117700186718
ko04260	Cardiac muscle contraction	12/408	98/7206	0.0121590189027
ko00020	Citrate cycle (TCA cycle)	6/408	35/7206	0.0127192989537
ko04621	NOD-like receptor signaling pathway	2/408	157/7206	0.0127777007556
ko00720	Carbon fixation pathways in prokaryotes	4/408	17/7206	0.0133729069307
ko05162	Measles	1/408	120/7206	0.0148122991682
ko04666	Fc gamma R-mediated phagocytosis	1/408	122/7206	0.0152692774495
ko00710	Carbon fixation in photosynthetic organisms	5/408	27/7206	0.0163016234365
ko00982	Drug metabolism - cytochrome P450	6/408	37/7206	0.0165686244161
ko04015	Rap1 signaling pathway	7/408	278/7206	0.0166846465075
ko04014	Ras signaling pathway	7/408	279/7206	0.0167211584487
ko00643	Styrene degradation	2/408	4/7206	0.0177785086231
ko01220	Degradation of aromatic compounds	2/408	4/7206	0.0177785086231
ko04922	Glucagon signaling pathway	14/408	128/7206	0.0178883229038
ko00250	Alanine, aspartate and glutamate metabolism	6/408	38/7206	0.0187656106513
ko04072	Phospholipase D signaling pathway	4/408	197/7206	0.0187763247137
ko04727	GABAergic synapse	1/408	110/7206	0.0209928321772
ko02010	ABC transporters	6/408	39/7206	0.0211535923253
ko04013	MAPK signaling pathway - fly	1/408	115/7206	0.0221028058873
ko00120	Primary bile acid biosynthesis	4/408	20/7206	0.0238131808833
ko04713	Circadian entrainment	2/408	136/7206	0.0243059328739
ko04114	Oocyte meiosis	2/408	139/7206	0.0244640402415
ko04060	Cytokine-cytokine receptor interaction	4/408	191/7206	0.0255421784364
ko04140	Autophagy - animal	3/408	164/7206	0.0255502996997
ko04550	Signaling pathways regulating pluripotency of stem cells	3/408	165/7206	0.0256037425725
ko05410	Hypertrophic cardiomyopathy (HCM)	11/408	100/7206	0.0281192834863
ko00472	D-Arginine and D-ornithine metabolism	2/408	5/7206	0.0285282467634
ko00232	Caffeine metabolism	2/408	5/7206	0.0285282467634
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	2/408	5/7206	0.0285282467634
ko00311	Penicillin and cephalosporin biosynthesis	2/408	5/7206	0.0285282467634
ko04350	TGF-beta signaling pathway	1/408	103/7206	0.0303232134039
ko04520	Adherens junction	1/408	103/7206	0.0303232134039
ko05133	Pertussis	10/408	87/7206	0.0305878846883
ko03010	Ribosome	2/408	129/7206	0.0341114300979
ko00520	Amino sugar and nucleotide sugar metabolism	7/408	55/7206	0.0343440209857
ko04630	Jak-STAT signaling pathway	2/408	132/7206	0.0344047828012
ko04380	Osteoclast differentiation	2/408	134/7206	0.0350134599887
ko04933	AGE-RAGE signaling pathway in diabetic complications	2/408	135/7206	0.0354415425821
ko00350	Tyrosine metabolism	5/408	33/7206	0.0363633536583
ko00860	Porphyrin and chlorophyll metabolism	5/408	34/7206	0.0407274138666
ko00770	Pantothenate and CoA biosynthesis	3/408	14/7206	0.0411354978594
ko05132	Salmonella infection	1/408	98/7206	0.0442494292662
ko04720	Long-term potentiation	1/408	99/7206	0.0447144087676
ko05203	Viral carcinogenesis	8/408	277/7206	0.0452467616329
ko00410	beta-Alanine metabolism	5/408	35/7206	0.0453954330188
ko00500	Starch and sucrose metabolism	5/408	35/7206	0.0453954330188
ko05206	MicroRNAs in cancer	4/408	177/7206	0.0467609245755
ko04912	GnRH signaling pathway	2/408	122/7206	0.0477178313798
ko05145	Toxoplasmosis	2/408	126/7206	0.0486100893784