ko pathway ratio_in_study ratio_in_pop p_value ko05033 Nicotine addiction 8/77 56/7206 1.10339945518e-07 ko04728 Dopaminergic synapse 12/77 185/7206 4.9130211393e-07 ko05030 Cocaine addiction 7/77 73/7206 1.11728688812e-05 ko04725 Cholinergic synapse 9/77 160/7206 4.64319668023e-05 ko05032 Morphine addiction 7/77 110/7206 0.000159169279208 ko04721 Synaptic vesicle cycle 6/77 80/7206 0.000196197836776 ko04727 GABAergic synapse 6/77 110/7206 0.00108584588345 ko04921 Oxytocin signaling pathway 8/77 209/7206 0.00165289477331 ko04723 Retrograde endocannabinoid signaling 7/77 175/7206 0.00254133385497 ko05031 Amphetamine addiction 5/77 91/7206 0.00277883238206 ko04080 Neuroactive ligand-receptor interaction 11/77 423/7206 0.00499078352253 ko04010 MAPK signaling pathway 9/77 321/7206 0.00689991626002 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 4/77 79/7206 0.00989022562186 ko05034 Alcoholism 7/77 238/7206 0.0132486373706 ko04726 Serotonergic synapse 5/77 137/7206 0.0152880145626 ko00910 Nitrogen metabolism 2/77 19/7206 0.017134532507 ko04930 Type II diabetes mellitus 3/77 54/7206 0.019701287289 ko01051 Biosynthesis of ansamycins 1/77 2/7206 0.0212583661202 ko05012 Parkinson's disease 5/77 155/7206 0.024674437469 ko04024 cAMP signaling pathway 7/77 279/7206 0.0289040620408 ko04964 Proximal tubule bicarbonate reclamation 2/77 29/7206 0.0379898735328 ko05142 Chagas disease (American trypanosomiasis) 4/77 130/7206 0.0499130378175