ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	123/724	423/7206	4.035925095e-30
ko05033	Nicotine addiction	40/724	56/7206	3.91039735426e-28
ko04724	Glutamatergic synapse	65/724	152/7206	1.70256756434e-26
ko04727	GABAergic synapse	46/724	110/7206	1.47319346567e-18
ko05032	Morphine addiction	46/724	110/7206	1.47319346567e-18
ko04024	cAMP signaling pathway	76/724	279/7206	7.13863018452e-17
ko04713	Circadian entrainment	48/724	136/7206	8.92158574871e-16
ko04728	Dopaminergic synapse	57/724	185/7206	1.85465163157e-15
ko04725	Cholinergic synapse	52/724	160/7206	2.86279678581e-15
ko04723	Retrograde endocannabinoid signaling	54/724	175/7206	9.86959525245e-15
ko04721	Synaptic vesicle cycle	33/724	80/7206	1.88639882416e-13
ko04911	Insulin secretion	38/724	117/7206	1.79153986351e-11
ko04261	Adrenergic signaling in cardiomyocytes	53/724	205/7206	4.03820418017e-11
ko04020	Calcium signaling pathway	60/724	265/7206	8.78189382386e-10
ko04360	Axon guidance	54/724	233/7206	2.46444072495e-09
ko04726	Serotonergic synapse	37/724	137/7206	1.08645867972e-08
ko05030	Cocaine addiction	25/724	73/7206	1.60842196207e-08
ko04921	Oxytocin signaling pathway	48/724	209/7206	2.76998658314e-08
ko04742	Taste transduction	22/724	61/7206	4.02589943848e-08
ko04010	MAPK signaling pathway	64/724	321/7206	5.73097469157e-08
ko05031	Amphetamine addiction	27/724	91/7206	1.32892607756e-07
ko04514	Cell adhesion molecules (CAMs)	33/724	130/7206	3.35882087765e-07
ko04744	Phototransduction	15/724	36/7206	6.87878098462e-07
ko04720	Long-term potentiation	27/724	99/7206	8.6764597323e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	22/724	74/7206	1.86467588026e-06
ko03040	Spliceosome	1/724	145/7206	4.83621627143e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/724	79/7206	2.18691322451e-05
ko05203	Viral carcinogenesis	9/724	277/7206	2.32623968099e-05
ko04022	cGMP-PKG signaling pathway	42/724	216/7206	2.507037084e-05
ko03013	RNA transport	3/724	166/7206	3.94344091461e-05
ko04970	Salivary secretion	23/724	95/7206	4.60551822702e-05
ko04260	Cardiac muscle contraction	23/724	98/7206	0.000106388534561
ko05322	Systemic lupus erythematosus	3/724	151/7206	0.000172153614069
ko00240	Pyrimidine metabolism	1/724	110/7206	0.000174968511983
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/724	14/7206	0.000183038853436
ko04925	Aldosterone synthesis and secretion	23/724	105/7206	0.000248515094773
ko05414	Dilated cardiomyopathy	24/724	112/7206	0.00033476078749
ko04060	Cytokine-cytokine receptor interaction	6/724	191/7206	0.000531936387063
ko04972	Pancreatic secretion	23/724	111/7206	0.000645536070276
ko04730	Long-term depression	18/724	78/7206	0.000813696192072
ko05164	Influenza A	5/724	167/7206	0.000956518040245
ko05168	Herpes simplex infection	6/724	182/7206	0.00100569858688
ko05410	Hypertrophic cardiomyopathy (HCM)	21/724	100/7206	0.00107142627047
ko01200	Carbon metabolism	3/724	128/7206	0.00152252039135
ko04072	Phospholipase D signaling pathway	34/724	197/7206	0.00158148549497
ko04930	Type II diabetes mellitus	13/724	54/7206	0.00214789095034
ko04141	Protein processing in endoplasmic reticulum	7/724	184/7206	0.0025933264079
ko03018	RNA degradation	1/724	84/7206	0.00278986885172
ko04915	Estrogen signaling pathway	24/724	131/7206	0.00308623596683
ko04610	Complement and coagulation cascades	1/724	79/7206	0.00402812737545
ko03008	Ribosome biogenesis in eukaryotes	1/724	79/7206	0.00402812737545
ko05169	Epstein-Barr virus infection	9/724	206/7206	0.00440248966766
ko05205	Proteoglycans in cancer	14/724	271/7206	0.00512830321555
ko04971	Gastric acid secretion	19/724	98/7206	0.00570877553894
ko04924	Renin secretion	17/724	86/7206	0.00578631852378
ko04621	NOD-like receptor signaling pathway	6/724	157/7206	0.0066397456881
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/724	59/7206	0.00679121458526
ko04146	Peroxisome	2/724	89/7206	0.0074671086588
ko00310	Lysine degradation	1/724	73/7206	0.00915361941578
ko04120	Ubiquitin mediated proteolysis	5/724	138/7206	0.00918986242815
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/724	182/7206	0.0172075338852
ko00561	Glycerolipid metabolism	1/724	63/7206	0.0186944252538
ko04640	Hematopoietic cell lineage	1/724	64/7206	0.0190598174713
ko04612	Antigen processing and presentation	2/724	77/7206	0.0216676449961
ko04964	Proximal tubule bicarbonate reclamation	7/724	29/7206	0.0218867827517
ko05161	Hepatitis B	9/724	173/7206	0.0291149887132
ko05162	Measles	5/724	120/7206	0.0305374244269
ko00010	Glycolysis / Gluconeogenesis	2/724	74/7206	0.0308686860935
ko05140	Leishmaniasis	2/724	75/7206	0.0312585790891
ko04350	TGF-beta signaling pathway	4/724	103/7206	0.0314244540714
ko00515	Mannose type O-glycan biosynthesis	6/724	25/7206	0.0338203324551
ko04110	Cell cycle	7/724	145/7206	0.0351186664255
ko04976	Bile secretion	14/724	80/7206	0.0370332380783
ko00480	Glutathione metabolism	1/724	55/7206	0.0398701940354
ko05321	Inflammatory bowel disease (IBD)	1/724	56/7206	0.0406469706734
ko05012	Parkinson's disease	8/724	155/7206	0.0417225933712
ko04371	Apelin signaling pathway	26/724	177/7206	0.0426205971563
ko00564	Glycerophospholipid metabolism	4/724	99/7206	0.0427376664074
ko03320	PPAR signaling pathway	2/724	69/7206	0.0434494176336
ko04217	Necroptosis	10/724	178/7206	0.0435137843784
ko01230	Biosynthesis of amino acids	3/724	85/7206	0.0442120699309
ko04214	Apoptosis - fly	2/724	72/7206	0.0451930771833
ko05133	Pertussis	3/724	87/7206	0.0454613243978
ko04140	Autophagy - animal	9/724	164/7206	0.0484291856793