ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	52/471	145/7206	5.49314275873e-26
ko03440	Homologous recombination	25/471	41/7206	5.06849926773e-20
ko03008	Ribosome biogenesis in eukaryotes	32/471	79/7206	3.31490301091e-18
ko05322	Systemic lupus erythematosus	40/471	151/7206	5.85087857694e-15
ko03013	RNA transport	42/471	166/7206	6.92275540073e-15
ko04110	Cell cycle	39/471	145/7206	7.48935170405e-15
ko03460	Fanconi anemia pathway	22/471	51/7206	1.41805783275e-13
ko04111	Cell cycle - yeast	28/471	90/7206	1.06991133103e-12
ko03030	DNA replication	16/471	38/7206	5.03075946154e-10
ko04113	Meiosis - yeast	20/471	70/7206	1.02824093506e-08
ko05034	Alcoholism	40/471	238/7206	2.06379537671e-08
ko00240	Pyrimidine metabolism	25/471	110/7206	2.53854776349e-08
ko03018	RNA degradation	21/471	84/7206	5.84819909944e-08
ko04020	Calcium signaling pathway	1/471	265/7206	3.87590422038e-07
ko04144	Endocytosis	4/471	342/7206	1.65222874194e-06
ko03430	Mismatch repair	9/471	22/7206	4.66150239762e-06
ko03420	Nucleotide excision repair	13/471	46/7206	4.66370446666e-06
ko03020	RNA polymerase	10/471	29/7206	8.36891105123e-06
ko04024	cAMP signaling pathway	3/471	279/7206	1.12107585894e-05
ko03410	Base excision repair	11/471	38/7206	1.97819954876e-05
ko04510	Focal adhesion	2/471	240/7206	2.45746992067e-05
ko04151	PI3K-Akt signaling pathway	8/471	390/7206	5.00760032321e-05
ko05152	Tuberculosis	1/471	187/7206	6.72248409787e-05
ko04728	Dopaminergic synapse	1/471	185/7206	0.000105944406018
ko04022	cGMP-PKG signaling pathway	2/471	216/7206	0.000112035731982
ko04723	Retrograde endocannabinoid signaling	1/471	175/7206	0.00014656220506
ko05203	Viral carcinogenesis	35/471	277/7206	0.000154049392937
ko04261	Adrenergic signaling in cardiomyocytes	2/471	205/7206	0.000155701876598
ko04921	Oxytocin signaling pathway	2/471	209/7206	0.000160016977974
ko05010	Alzheimer's disease	2/471	202/7206	0.000229137119545
ko03015	mRNA surveillance pathway	16/471	93/7206	0.000300994931535
ko04611	Platelet activation	1/471	163/7206	0.000318226700345
ko03022	Basal transcription factors	10/471	44/7206	0.000426122689097
ko04060	Cytokine-cytokine receptor interaction	2/471	191/7206	0.000489426146316
ko04724	Glutamatergic synapse	1/471	152/7206	0.000693996120685
ko04114	Oocyte meiosis	20/471	139/7206	0.000730461554338
ko04010	MAPK signaling pathway	8/471	321/7206	0.00115126732511
ko04062	Chemokine signaling pathway	3/471	201/7206	0.00122744510899
ko04713	Circadian entrainment	1/471	136/7206	0.00226816745537
ko04725	Cholinergic synapse	2/471	160/7206	0.00299767179306
ko05145	Toxoplasmosis	1/471	126/7206	0.00315494162257
ko00190	Oxidative phosphorylation	1/471	127/7206	0.00317083170458
ko05142	Chagas disease (American trypanosomiasis)	1/471	130/7206	0.00331966428773
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/471	182/7206	0.00344739773864
ko04530	Tight junction	5/471	228/7206	0.00391155024481
ko04015	Rap1 signaling pathway	7/471	278/7206	0.00400644338089
ko04142	Lysosome	2/471	151/7206	0.00415862970004
ko05012	Parkinson's disease	2/471	155/7206	0.00437969396964
ko04750	Inflammatory mediator regulation of TRP channels	1/471	122/7206	0.00468060221697
ko04911	Insulin secretion	1/471	117/7206	0.00693850651079
ko04810	Regulation of actin cytoskeleton	7/471	264/7206	0.00713383222577
ko05166	HTLV-I infection	31/471	292/7206	0.0072924984934
ko04914	Progesterone-mediated oocyte maturation	14/471	104/7206	0.00827314104991
ko04726	Serotonergic synapse	2/471	137/7206	0.00841474418217
ko04071	Sphingolipid signaling pathway	3/471	162/7206	0.0094154232678
ko04727	GABAergic synapse	1/471	110/7206	0.00995045868983
ko05032	Morphine addiction	1/471	110/7206	0.00995045868983
ko04915	Estrogen signaling pathway	2/471	131/7206	0.011936697418
ko04630	Jak-STAT signaling pathway	2/471	132/7206	0.0119572729739
ko04380	Osteoclast differentiation	2/471	134/7206	0.0121341961396
ko03450	Non-homologous end-joining	4/471	15/7206	0.0137948555975
ko01200	Carbon metabolism	2/471	128/7206	0.0172170695072
ko04514	Cell adhesion molecules (CAMs)	2/471	130/7206	0.0177425409354
ko04072	Phospholipase D signaling pathway	5/471	197/7206	0.0182874452931
ko04910	Insulin signaling pathway	4/471	172/7206	0.0184622445315
ko04014	Ras signaling pathway	9/471	279/7206	0.0185766331602
ko04970	Salivary secretion	1/471	95/7206	0.0205309801664
ko04974	Protein digestion and absorption	1/471	96/7206	0.0206024828177
ko04260	Cardiac muscle contraction	1/471	98/7206	0.0210212882914
ko04720	Long-term potentiation	1/471	99/7206	0.0213692428573
ko00564	Glycerophospholipid metabolism	1/471	99/7206	0.0213692428573
ko04620	Toll-like receptor signaling pathway	1/471	100/7206	0.0218102065421
ko04912	GnRH signaling pathway	2/471	122/7206	0.0243622302076
ko00230	Purine metabolism	21/471	194/7206	0.0254574826082
ko04115	p53 signaling pathway	10/471	74/7206	0.027930597378
ko04146	Peroxisome	1/471	89/7206	0.0297108832444
ko04920	Adipocytokine signaling pathway	1/471	89/7206	0.0297108832444
ko04141	Protein processing in endoplasmic reticulum	5/471	184/7206	0.0329247093145
ko04070	Phosphatidylinositol signaling system	2/471	112/7206	0.0335060266207
ko04152	AMPK signaling pathway	4/471	161/7206	0.0343676660329
ko04933	AGE-RAGE signaling pathway in diabetic complications	3/471	135/7206	0.034571185124
ko04145	Phagosome	4/471	162/7206	0.0346321329698
ko04137	Mitophagy - animal	1/471	82/7206	0.042869404182
ko04371	Apelin signaling pathway	5/471	177/7206	0.043778454516
ko04924	Renin secretion	1/471	86/7206	0.0440839126187
ko04918	Thyroid hormone synthesis	1/471	86/7206	0.0440839126187
ko04210	Apoptosis	5/471	180/7206	0.0448134060185
ko05133	Pertussis	1/471	87/7206	0.0448189679508
ko05160	Hepatitis C	4/471	153/7206	0.0460636672332
ko04659	Th17 cell differentiation	2/471	106/7206	0.0469616408206
ko04925	Aldosterone synthesis and secretion	2/471	105/7206	0.0469825348607
ko04922	Glucagon signaling pathway	3/471	128/7206	0.047453572754
ko04972	Pancreatic secretion	2/471	111/7206	0.0490237044414