ko pathway ratio_in_study ratio_in_pop p_value ko04380 Osteoclast differentiation 13/150 134/7206 3.70910718509e-06 ko04725 Cholinergic synapse 13/150 160/7206 2.58246800046e-05 ko05164 Influenza A 12/150 167/7206 0.000174583153634 ko04668 TNF signaling pathway 10/150 120/7206 0.000185218390801 ko05214 Glioma 8/150 79/7206 0.000218577239711 ko05230 Central carbon metabolism in cancer 8/150 81/7206 0.000260195232665 ko04626 Plant-pathogen interaction 4/150 18/7206 0.000439671528194 ko04662 B cell receptor signaling pathway 8/150 88/7206 0.000459972758115 ko04722 Neurotrophin signaling pathway 11/150 160/7206 0.000477979713315 ko05031 Amphetamine addiction 8/150 91/7206 0.000577068642676 ko05167 Kaposi's sarcoma-associated herpesvirus infection 12/150 191/7206 0.000600279650819 ko04650 Natural killer cell mediated cytotoxicity 8/150 97/7206 0.000883561604051 ko04750 Inflammatory mediator regulation of TRP channels 9/150 122/7206 0.000951890499181 ko04720 Long-term potentiation 8/150 99/7206 0.0010107319521 ko04370 VEGF signaling pathway 7/150 77/7206 0.00104656472814 ko04610 Complement and coagulation cascades 7/150 79/7206 0.00121865113965 ko05212 Pancreatic cancer 7/150 83/7206 0.00162893575703 ko05220 Chronic myeloid leukemia 7/150 85/7206 0.00187077513065 ko05215 Prostate cancer 8/150 111/7206 0.00211415688321 ko04912 GnRH signaling pathway 8/150 122/7206 0.00380690857318 ko04217 Necroptosis 10/150 178/7206 0.00388954284202 ko04660 T cell receptor signaling pathway 8/150 124/7206 0.00420377359916 ko05160 Hepatitis C 9/150 153/7206 0.00451043714743 ko04664 Fc epsilon RI signaling pathway 6/150 77/7206 0.00517902168586 ko04915 Estrogen signaling pathway 8/150 131/7206 0.00584895142207 ko04060 Cytokine-cytokine receptor interaction 10/150 191/7206 0.00637211505866 ko04012 ErbB signaling pathway 7/150 109/7206 0.00747312211528 ko04024 cAMP signaling pathway 13/150 279/7206 0.00778693246122 ko04068 FoxO signaling pathway 9/150 167/7206 0.00792371986111 ko04062 Chemokine signaling pathway 10/150 201/7206 0.00901081755521 ko05213 Endometrial cancer 5/150 62/7206 0.00912439318406 ko04360 Axon guidance 11/150 233/7206 0.00914785524545 ko05221 Acute myeloid leukemia 5/150 63/7206 0.00974871553888 ko04919 Thyroid hormone signaling pathway 8/150 143/7206 0.0097574479177 ko05161 Hepatitis B 9/150 173/7206 0.00987956288082 ko04960 Aldosterone-regulated sodium reabsorption 4/150 41/7206 0.0100477598781 ko04218 Cellular senescence 9/150 177/7206 0.0113730424831 ko04921 Oxytocin signaling pathway 10/150 209/7206 0.0116697784951 ko05223 Non-small cell lung cancer 5/150 66/7206 0.0117968474142 ko04710 Circadian rhythm 4/150 43/7206 0.011859651259 ko04210 Apoptosis 9/150 180/7206 0.0125999377631 ko04670 Leukocyte transendothelial migration 8/150 151/7206 0.0132751080014 ko04211 Longevity regulating pathway 7/150 123/7206 0.0140185954973 ko05211 Renal cell carcinoma 6/150 96/7206 0.0146969802497 ko04922 Glucagon signaling pathway 7/150 128/7206 0.0171312277548 ko04620 Toll-like receptor signaling pathway 6/150 100/7206 0.0176704082733 ko01524 Platinum drug resistance 5/150 76/7206 0.0206910029756 ko04140 Autophagy - animal 8/150 164/7206 0.0208533268842 ko05231 Choline metabolism in cancer 7/150 134/7206 0.0214768216992 ko04072 Phospholipase D signaling pathway 9/150 197/7206 0.0214952240364 ko04923 Regulation of lipolysis in adipocytes 5/150 77/7206 0.0217682238986 ko04925 Aldosterone synthesis and secretion 6/150 105/7206 0.0219381035741 ko04933 AGE-RAGE signaling pathway in diabetic complications 7/150 135/7206 0.0222692315065 ko04931 Insulin resistance 7/150 137/7206 0.0239145299477 ko04020 Calcium signaling pathway 11/150 265/7206 0.025481850939 ko04930 Type II diabetes mellitus 4/150 54/7206 0.0255176003351 ko05418 Fluid shear stress and atherosclerosis 8/150 173/7206 0.0276400211553 ko04070 Phosphatidylinositol signaling system 6/150 112/7206 0.0290103048119 ko05218 Melanoma 5/150 85/7206 0.0317091545773 ko04213 Longevity regulating pathway - multiple species 5/150 86/7206 0.033122018956 ko05210 Colorectal cancer 5/150 86/7206 0.033122018956 ko04924 Renin secretion 5/150 86/7206 0.033122018956 ko04917 Prolactin signaling pathway 5/150 87/7206 0.0345736267558 ko05222 Small cell lung cancer 5/150 89/7206 0.0375939432687 ko05162 Measles 6/150 120/7206 0.0387641916274 ko04261 Adrenergic signaling in cardiomyocytes 9/150 205/7206 0.0395509948324 ko04066 HIF-1 signaling pathway 6/150 123/7206 0.0429020644269 ko04745 Phototransduction - fly 3/150 38/7206 0.0438750184425 ko04621 NOD-like receptor signaling pathway 7/150 157/7206 0.0451355064048 ko04022 cGMP-PKG signaling pathway 9/150 216/7206 0.0459199161835 ko05145 Toxoplasmosis 6/150 126/7206 0.0473084655242 ko04014 Ras signaling pathway 11/150 279/7206 0.0487523105619