ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	83/711	145/7206	8.05492443491e-47
ko04110	Cell cycle	70/711	145/7206	4.08340115157e-33
ko04111	Cell cycle - yeast	49/711	90/7206	1.65370090258e-26
ko03030	DNA replication	30/711	38/7206	8.64297160389e-24
ko04080	Neuroactive ligand-receptor interaction	1/711	423/7206	1.81173292419e-18
ko03013	RNA transport	57/711	166/7206	2.91051950395e-18
ko03460	Fanconi anemia pathway	30/711	51/7206	5.77950848479e-18
ko04113	Meiosis - yeast	34/711	70/7206	1.0479502033e-16
ko03008	Ribosome biogenesis in eukaryotes	36/711	79/7206	1.74046054449e-16
ko03440	Homologous recombination	25/711	41/7206	1.07362449687e-15
ko03410	Base excision repair	22/711	38/7206	2.64309535295e-13
ko03430	Mismatch repair	16/711	22/7206	2.9148545437e-12
ko03420	Nucleotide excision repair	23/711	46/7206	4.78132905133e-12
ko03015	mRNA surveillance pathway	31/711	93/7206	4.1185098011e-10
ko04020	Calcium signaling pathway	2/711	265/7206	6.44769065647e-10
ko04144	Endocytosis	7/711	342/7206	7.97388643185e-09
ko00240	Pyrimidine metabolism	31/711	110/7206	3.86519401941e-08
ko04932	Non-alcoholic fatty liver disease (NAFLD)	1/711	182/7206	1.96113956735e-07
ko03018	RNA degradation	25/711	84/7206	2.5647332606e-07
ko04060	Cytokine-cytokine receptor interaction	2/711	191/7206	8.49362372445e-07
ko05012	Parkinson's disease	1/711	155/7206	3.47130877554e-06
ko04621	NOD-like receptor signaling pathway	2/711	157/7206	1.89607784965e-05
ko05166	HTLV-I infection	52/711	292/7206	2.01863251091e-05
ko04022	cGMP-PKG signaling pathway	5/711	216/7206	2.19180821292e-05
ko04072	Phospholipase D signaling pathway	4/711	197/7206	2.63023062731e-05
ko04723	Retrograde endocannabinoid signaling	3/711	175/7206	2.78250429634e-05
ko04724	Glutamatergic synapse	2/711	152/7206	4.32277284912e-05
ko04062	Chemokine signaling pathway	5/711	201/7206	6.17103406167e-05
ko04330	Notch signaling pathway	17/711	62/7206	6.85646962462e-05
ko04014	Ras signaling pathway	10/711	279/7206	8.64611326374e-05
ko04911	Insulin secretion	1/711	117/7206	0.000120164256765
ko04725	Cholinergic synapse	3/711	160/7206	0.000126205414822
ko04726	Serotonergic synapse	2/711	137/7206	0.000128184580227
ko04921	Oxytocin signaling pathway	6/711	209/7206	0.000138128388822
ko04261	Adrenergic signaling in cardiomyocytes	6/711	205/7206	0.000193261610361
ko04933	AGE-RAGE signaling pathway in diabetic complications	2/711	135/7206	0.000193533384965
ko03022	Basal transcription factors	13/711	44/7206	0.00021574461837
ko05217	Basal cell carcinoma	17/711	68/7206	0.000236623920842
ko04514	Cell adhesion molecules (CAMs)	2/711	130/7206	0.000276291504118
ko04972	Pancreatic secretion	1/711	111/7206	0.000281237365683
ko04915	Estrogen signaling pathway	2/711	131/7206	0.000282890923824
ko04024	cAMP signaling pathway	11/711	279/7206	0.000295187254355
ko04660	T cell receptor signaling pathway	2/711	124/7206	0.000397267141424
ko04114	Oocyte meiosis	27/711	139/7206	0.000480498225098
ko04151	PI3K-Akt signaling pathway	20/711	390/7206	0.000634470276465
ko04910	Insulin signaling pathway	5/711	172/7206	0.0006748978059
ko04713	Circadian entrainment	3/711	136/7206	0.000734709529719
ko04218	Cellular senescence	32/711	177/7206	0.000751180917045
ko05322	Systemic lupus erythematosus	28/711	151/7206	0.000840125554169
ko04270	Vascular smooth muscle contraction	4/711	154/7206	0.000871613939066
ko04971	Gastric acid secretion	1/711	98/7206	0.000883392108219
ko04380	Osteoclast differentiation	3/711	134/7206	0.00106762588488
ko05231	Choline metabolism in cancer	3/711	134/7206	0.00106762588488
ko04070	Phosphatidylinositol signaling system	2/711	112/7206	0.00121248038321
ko04142	Lysosome	4/711	151/7206	0.00126062187997
ko05120	Epithelial cell signaling in Helicobacter pylori infection	1/711	92/7206	0.00126073043301
ko04510	Focal adhesion	10/711	240/7206	0.00131207259723
ko04010	MAPK signaling pathway	16/711	321/7206	0.00152073593102
ko04727	GABAergic synapse	2/711	110/7206	0.00179695536469
ko05032	Morphine addiction	2/711	110/7206	0.00179695536469
ko04722	Neurotrophin signaling pathway	5/711	160/7206	0.00182628728849
ko04146	Peroxisome	1/711	89/7206	0.00188416829403
ko04371	Apelin signaling pathway	6/711	177/7206	0.00192884579795
ko04015	Rap1 signaling pathway	13/711	278/7206	0.00194452689462
ko04810	Regulation of actin cytoskeleton	12/711	264/7206	0.00210987485176
ko04925	Aldosterone synthesis and secretion	2/711	105/7206	0.00255260413247
ko04728	Dopaminergic synapse	7/711	185/7206	0.00258045256114
ko04659	Th17 cell differentiation	2/711	106/7206	0.00260081739461
ko01521	EGFR tyrosine kinase inhibitor resistance	2/711	106/7206	0.00260081739461
ko04668	TNF signaling pathway	3/711	120/7206	0.00301292015447
ko04912	GnRH signaling pathway	3/711	122/7206	0.00309624944194
ko04530	Tight junction	10/711	228/7206	0.0031155901526
ko04670	Leukocyte transendothelial migration	5/711	151/7206	0.00348163589641
ko05160	Hepatitis C	5/711	153/7206	0.00355978182901
ko04620	Toll-like receptor signaling pathway	2/711	100/7206	0.00364786561291
ko00564	Glycerophospholipid metabolism	2/711	99/7206	0.00364886221045
ko04914	Progesterone-mediated oocyte maturation	20/711	104/7206	0.00402148163245
ko04610	Complement and coagulation cascades	1/711	79/7206	0.00403494616406
ko04071	Sphingolipid signaling pathway	6/711	162/7206	0.00481278020151
ko04120	Ubiquitin mediated proteolysis	24/711	138/7206	0.00556302128321
ko04370	VEGF signaling pathway	1/711	77/7206	0.00603425065957
ko04923	Regulation of lipolysis in adipocytes	1/711	77/7206	0.00603425065957
ko05152	Tuberculosis	8/711	187/7206	0.00609098240165
ko04730	Long-term depression	1/711	78/7206	0.00619612847576
ko00230	Purine metabolism	31/711	194/7206	0.00676655249467
ko05203	Viral carcinogenesis	41/711	277/7206	0.0073257476873
ko04139	Mitophagy - yeast	9/711	37/7206	0.00833214103598
ko04012	ErbB signaling pathway	3/711	109/7206	0.00861234800909
ko04750	Inflammatory mediator regulation of TRP channels	4/711	122/7206	0.00888821863837
ko04066	HIF-1 signaling pathway	4/711	123/7206	0.00891020579173
ko04931	Insulin resistance	5/711	137/7206	0.00898869011761
ko00670	One carbon pool by folate	6/711	20/7206	0.0104504646441
ko00562	Inositol phosphate metabolism	2/711	89/7206	0.0109399249203
ko04140	Autophagy - animal	7/711	164/7206	0.0114051260798
ko03450	Non-homologous end-joining	5/711	15/7206	0.0119448991961
ko04360	Axon guidance	12/711	233/7206	0.0133939486527
ko04152	AMPK signaling pathway	7/711	161/7206	0.0153176549353
ko04145	Phagosome	7/711	162/7206	0.0154938830956
ko04924	Renin secretion	2/711	86/7206	0.0160231191649
ko05168	Herpes simplex infection	28/711	182/7206	0.016168242672
ko04115	p53 signaling pathway	14/711	74/7206	0.0163448823343
ko05132	Salmonella infection	3/711	98/7206	0.0165467688833
ko05146	Amoebiasis	3/711	99/7206	0.0165810396679
ko05142	Chagas disease (American trypanosomiasis)	5/711	130/7206	0.0167038611571
ko05222	Small cell lung cancer	16/711	89/7206	0.0179694007394
ko05110	Vibrio cholerae infection	1/711	63/7206	0.0186400942851
ko04913	Ovarian steroidogenesis	1/711	63/7206	0.0186400942851
ko00561	Glycerolipid metabolism	1/711	63/7206	0.0186400942851
ko03020	RNA polymerase	7/711	29/7206	0.0199867797788
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	2/711	79/7206	0.0218022564242
ko04138	Autophagy - yeast	2/711	81/7206	0.022336688214
ko04137	Mitophagy - animal	2/711	82/7206	0.022879060967
ko04540	Gap junction	5/711	128/7206	0.0232843655964
ko04064	NF-kappa B signaling pathway	3/711	96/7206	0.0233850752542
ko05202	Transcriptional misregulation in cancer	28/711	188/7206	0.025033157848
ko00310	Lysine degradation	13/711	73/7206	0.0293502511285
ko05140	Leishmaniasis	2/711	75/7206	0.0309432832626
ko04211	Longevity regulating pathway	5/711	123/7206	0.0309980955271
ko04664	Fc epsilon RI signaling pathway	2/711	77/7206	0.0317802322003
ko05031	Amphetamine addiction	3/711	91/7206	0.0321724447009
ko04611	Platelet activation	8/711	163/7206	0.032377604813
ko04630	Jak-STAT signaling pathway	6/711	132/7206	0.038068442471
ko04962	Vasopressin-regulated water reabsorption	1/711	58/7206	0.0419573177909
ko04310	Wnt signaling pathway	26/711	181/7206	0.0436668040488
ko04213	Longevity regulating pathway - multiple species	3/711	86/7206	0.0442538339226
ko04917	Prolactin signaling pathway	3/711	87/7206	0.0445792373078
ko05133	Pertussis	3/711	87/7206	0.0445792373078
ko05030	Cocaine addiction	2/711	73/7206	0.0450663757376
ko05323	Rheumatoid arthritis	3/711	89/7206	0.0460390699901
ko04550	Signaling pathways regulating pluripotency of stem cells	24/711	165/7206	0.0472332334533