ko pathway ratio_in_study ratio_in_pop p_value ko00120 Primary bile acid biosynthesis 11/533 20/7206 2.97994841978e-08 ko04380 Osteoclast differentiation 29/533 134/7206 9.91906494626e-08 ko04137 Mitophagy - animal 20/533 82/7206 1.36768835759e-06 ko05321 Inflammatory bowel disease (IBD) 15/533 56/7206 8.43783403326e-06 ko04621 NOD-like receptor signaling pathway 28/533 157/7206 1.46421500755e-05 ko04060 Cytokine-cytokine receptor interaction 30/533 191/7206 6.51546081137e-05 ko04650 Natural killer cell mediated cytotoxicity 19/533 97/7206 7.07924169247e-05 ko03320 PPAR signaling pathway 15/533 69/7206 0.000119724350109 ko00051 Fructose and mannose metabolism 11/533 42/7206 0.000169286157315 ko04064 NF-kappa B signaling pathway 18/533 96/7206 0.00019571546658 ko04710 Circadian rhythm 11/533 43/7206 0.00021256262214 ko05340 Primary immunodeficiency 9/533 30/7206 0.000216515277593 ko04146 Peroxisome 17/533 89/7206 0.000232164924626 ko05152 Tuberculosis 28/533 187/7206 0.000303573736024 ko03040 Spliceosome 1/533 145/7206 0.000307022258094 ko05140 Leishmaniasis 15/533 75/7206 0.000318349958466 ko05145 Toxoplasmosis 21/533 126/7206 0.000388171784683 ko05167 Kaposi's sarcoma-associated herpesvirus infection 28/533 191/7206 0.00039211426926 ko04068 FoxO signaling pathway 25/533 167/7206 0.000759572606831 ko05164 Influenza A 25/533 167/7206 0.000759572606831 ko03010 Ribosome 1/533 129/7206 0.000979178778855 ko04630 Jak-STAT signaling pathway 21/533 132/7206 0.00104955940979 ko04136 Autophagy - other 8/533 31/7206 0.00146121191534 ko05034 Alcoholism 6/533 238/7206 0.00151439319086 ko00620 Pyruvate metabolism 10/533 46/7206 0.00161493773298 ko01040 Biosynthesis of unsaturated fatty acids 7/533 25/7206 0.00172750006748 ko04610 Complement and coagulation cascades 14/533 79/7206 0.00174076682002 ko04110 Cell cycle 2/533 145/7206 0.00197234155102 ko04659 Th17 cell differentiation 17/533 106/7206 0.00211849738879 ko03013 RNA transport 3/533 166/7206 0.00236742744934 ko00140 Steroid hormone biosynthesis 9/533 41/7206 0.00255086944883 ko04662 B cell receptor signaling pathway 15/533 88/7206 0.00292115199613 ko04620 Toll-like receptor signaling pathway 16/533 100/7206 0.00298366655019 ko01212 Fatty acid metabolism 11/533 60/7206 0.00402420680038 ko05150 Staphylococcus aureus infection 8/533 36/7206 0.00403943007671 ko04658 Th1 and Th2 cell differentiation 15/533 96/7206 0.00491769529803 ko05144 Malaria 9/533 45/7206 0.00495380686578 ko00071 Fatty acid degradation 9/533 45/7206 0.00495380686578 ko00362 Benzoate degradation 3/533 6/7206 0.00679501714852 ko05162 Measles 17/533 120/7206 0.00783868543586 ko04390 Hippo signaling pathway 5/533 188/7206 0.01007289832 ko00380 Tryptophan metabolism 9/533 50/7206 0.0100804171406 ko00592 alpha-Linolenic acid metabolism 5/533 19/7206 0.0105802682504 ko04310 Wnt signaling pathway 5/533 181/7206 0.0134240491998 ko04660 T cell receptor signaling pathway 17/533 124/7206 0.0135809385211 ko04111 Cell cycle - yeast 1/533 90/7206 0.0138344844575 ko04391 Hippo signaling pathway - fly 1/533 90/7206 0.0138344844575 ko03015 mRNA surveillance pathway 1/533 93/7206 0.0144061115799 ko04922 Glucagon signaling pathway 17/533 128/7206 0.0160209887732 ko04672 Intestinal immune network for IgA production 7/533 37/7206 0.0171124428717 ko00982 Drug metabolism - cytochrome P450 7/533 37/7206 0.0171124428717 ko04217 Necroptosis 22/533 178/7206 0.0188733669833 ko04668 TNF signaling pathway 16/533 120/7206 0.0202558993112 ko05168 Herpes simplex infection 22/533 182/7206 0.020696132177 ko05323 Rheumatoid arthritis 13/533 89/7206 0.0216784693227 ko04611 Platelet activation 20/533 163/7206 0.022320982849 ko04622 RIG-I-like receptor signaling pathway 10/533 62/7206 0.0230609901275 ko00561 Glycerolipid metabolism 10/533 63/7206 0.0240975785079 ko05161 Hepatitis B 21/533 173/7206 0.0257055789702 ko04670 Leukocyte transendothelial migration 19/533 151/7206 0.0258194206265 ko04664 Fc epsilon RI signaling pathway 11/533 77/7206 0.027892281376 ko05330 Allograft rejection 5/533 24/7206 0.0285032001304 ko00220 Arginine biosynthesis 5/533 24/7206 0.0285032001304 ko00350 Tyrosine metabolism 6/533 33/7206 0.0317746129557 ko00052 Galactose metabolism 6/533 33/7206 0.0317746129557 ko00950 Isoquinoline alkaloid biosynthesis 3/533 10/7206 0.0326211681258 ko05133 Pertussis 12/533 87/7206 0.035307470535 ko00640 Propanoate metabolism 6/533 34/7206 0.0362628656994 ko04626 Plant-pathogen interaction 4/533 18/7206 0.0394094800374 ko05332 Graft-versus-host disease 4/533 18/7206 0.0394094800374 ko05224 Breast cancer 6/533 174/7206 0.0399477489293 ko04723 Retrograde endocannabinoid signaling 6/533 175/7206 0.0399699343297 ko00500 Starch and sucrose metabolism 6/533 35/7206 0.041138295735 ko05160 Hepatitis C 18/533 153/7206 0.0423513516465 ko04070 Phosphatidylinositol signaling system 14/533 112/7206 0.0446855283784 ko04022 cGMP-PKG signaling pathway 24/533 216/7206 0.0460801731838 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/533 5/7206 0.0469992230541 ko00564 Glycerophospholipid metabolism 13/533 99/7206 0.0490647331618 ko05230 Central carbon metabolism in cancer 11/533 81/7206 0.0496522033683