ko pathway ratio_in_study ratio_in_pop p_value ko04380 Osteoclast differentiation 21/377 134/7206 5.26450267962e-06 ko05162 Measles 19/377 120/7206 1.2751674055e-05 ko05164 Influenza A 23/377 167/7206 1.71981789953e-05 ko05140 Leishmaniasis 14/377 75/7206 2.72596295604e-05 ko05145 Toxoplasmosis 18/377 126/7206 8.77918116823e-05 ko05321 Inflammatory bowel disease (IBD) 11/377 56/7206 0.000122869804506 ko04060 Cytokine-cytokine receptor interaction 23/377 191/7206 0.000175523650626 ko04621 NOD-like receptor signaling pathway 20/377 157/7206 0.000183134298865 ko00120 Primary bile acid biosynthesis 6/377 20/7206 0.000408093502246 ko05150 Staphylococcus aureus infection 8/377 36/7206 0.00043269093619 ko04217 Necroptosis 21/377 178/7206 0.000434914901766 ko04650 Natural killer cell mediated cytotoxicity 14/377 97/7206 0.000475762609222 ko04630 Jak-STAT signaling pathway 17/377 132/7206 0.000485482240777 ko04610 Complement and coagulation cascades 12/377 79/7206 0.000749147285661 ko00051 Fructose and mannose metabolism 8/377 42/7206 0.00128190959883 ko04710 Circadian rhythm 8/377 43/7206 0.00150452069493 ko04662 B cell receptor signaling pathway 12/377 88/7206 0.00196620817556 ko04620 Toll-like receptor signaling pathway 13/377 100/7206 0.00201285709427 ko04664 Fc epsilon RI signaling pathway 11/377 77/7206 0.00205610391377 ko05152 Tuberculosis 20/377 187/7206 0.00219633981474 ko03013 RNA transport 1/377 166/7206 0.00226765860102 ko00592 alpha-Linolenic acid metabolism 5/377 19/7206 0.00241208803926 ko05167 Kaposi's sarcoma-associated herpesvirus infection 20/377 191/7206 0.00262432651262 ko05160 Hepatitis C 17/377 153/7206 0.00279270006956 ko04660 T cell receptor signaling pathway 15/377 124/7206 0.00315826845389 ko04659 Th17 cell differentiation 13/377 106/7206 0.00339396879092 ko05340 Primary immunodeficiency 6/377 30/7206 0.00401098432993 ko04658 Th1 and Th2 cell differentiation 12/377 96/7206 0.00410764621822 ko05161 Hepatitis B 18/377 173/7206 0.00483819027622 ko00140 Steroid hormone biosynthesis 7/377 41/7206 0.00487376971685 ko04668 TNF signaling pathway 14/377 120/7206 0.00532057684243 ko04611 Platelet activation 17/377 163/7206 0.00636421795808 ko00350 Tyrosine metabolism 6/377 33/7206 0.00655513463957 ko03040 Spliceosome 1/377 145/7206 0.00711093065363 ko04070 Phosphatidylinositol signaling system 13/377 112/7206 0.00778197566239 ko04080 Neuroactive ligand-receptor interaction 11/377 423/7206 0.00933111375669 ko05168 Herpes simplex infection 18/377 182/7206 0.0099098036418 ko04137 Mitophagy - animal 10/377 82/7206 0.0100483200695 ko05310 Asthma 4/377 17/7206 0.0101917767535 ko04672 Intestinal immune network for IgA production 6/377 37/7206 0.011543697553 ko04666 Fc gamma R-mediated phagocytosis 13/377 122/7206 0.012385706894 ko00950 Isoquinoline alkaloid biosynthesis 3/377 10/7206 0.0129437382431 ko04622 RIG-I-like receptor signaling pathway 8/377 62/7206 0.0148082874941 ko03010 Ribosome 1/377 129/7206 0.0148423317339 ko00561 Glycerolipid metabolism 8/377 63/7206 0.0162153127559 ko00590 Arachidonic acid metabolism 7/377 52/7206 0.0177543321533 ko00564 Glycerophospholipid metabolism 11/377 99/7206 0.0186494018897 ko04390 Hippo signaling pathway 3/377 188/7206 0.0188061467495 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/377 5/7206 0.0245691474372 ko05034 Alcoholism 5/377 238/7206 0.0250970575407 ko03320 PPAR signaling pathway 8/377 69/7206 0.0267413200605 ko04711 Circadian rhythm - fly 3/377 13/7206 0.0274552283208 ko04064 NF-kappa B signaling pathway 10/377 96/7206 0.0334310704923 ko05330 Allograft rejection 4/377 24/7206 0.0341374426969 ko00220 Arginine biosynthesis 4/377 24/7206 0.0341374426969 ko04110 Cell cycle 2/377 145/7206 0.0352783715069 ko05224 Breast cancer 3/377 174/7206 0.0361679421742 ko04723 Retrograde endocannabinoid signaling 3/377 175/7206 0.0365047917435 ko00330 Arginine and proline metabolism 7/377 61/7206 0.0389080418888 ko01040 Biosynthesis of unsaturated fatty acids 4/377 25/7206 0.0390185470683 ko04210 Apoptosis 16/377 180/7206 0.039090875079 ko00982 Drug metabolism - cytochrome P450 5/377 37/7206 0.0419441145025 ko04350 TGF-beta signaling pathway 1/377 103/7206 0.0439957749005 ko05215 Prostate cancer 11/377 111/7206 0.0477890822891