ko pathway ratio_in_study ratio_in_pop p_value ko04512 ECM-receptor interaction 20/249 79/7206 1.18469744064e-12 ko04974 Protein digestion and absorption 20/249 96/7206 5.70896422501e-11 ko04510 Focal adhesion 29/249 240/7206 2.71490308886e-09 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 14/249 79/7206 4.01923680916e-07 ko04060 Cytokine-cytokine receptor interaction 21/249 191/7206 2.29319517476e-06 ko04666 Fc gamma R-mediated phagocytosis 16/249 122/7206 3.96042542633e-06 ko04151 PI3K-Akt signaling pathway 32/249 390/7206 4.47009129228e-06 ko05146 Amoebiasis 14/249 99/7206 6.6176938809e-06 ko05410 Hypertrophic cardiomyopathy (HCM) 13/249 100/7206 3.56843124692e-05 ko04810 Regulation of actin cytoskeleton 23/249 264/7206 3.72832741788e-05 ko05205 Proteoglycans in cancer 23/249 271/7206 5.62277978061e-05 ko04668 TNF signaling pathway 13/249 120/7206 0.000237747201298 ko04640 Hematopoietic cell lineage 9/249 64/7206 0.000317431611741 ko05414 Dilated cardiomyopathy 12/249 112/7206 0.000456056930094 ko05200 Pathways in cancer 32/249 492/7206 0.000461050771956 ko04933 AGE-RAGE signaling pathway in diabetic complications 13/249 135/7206 0.000749825084572 ko04658 Th1 and Th2 cell differentiation 10/249 96/7206 0.00167498712346 ko05131 Shigellosis 9/249 82/7206 0.00196862446875 ko04380 Osteoclast differentiation 12/249 134/7206 0.00222438900468 ko04623 Cytosolic DNA-sensing pathway 6/249 41/7206 0.00260863813301 ko00565 Ether lipid metabolism 6/249 42/7206 0.00295712042077 ko04621 NOD-like receptor signaling pathway 13/249 157/7206 0.0029684419058 ko04912 GnRH signaling pathway 11/249 122/7206 0.0031875517525 ko05034 Alcoholism 1/249 238/7206 0.00340059696723 ko04916 Melanogenesis 12/249 142/7206 0.00360213494295 ko04611 Platelet activation 13/249 163/7206 0.00410373921287 ko04144 Endocytosis 22/249 342/7206 0.00547131827379 ko05100 Bacterial invasion of epithelial cells 9/249 99/7206 0.00700499654419 ko05161 Hepatitis B 13/249 173/7206 0.00887146521785 ko04350 TGF-beta signaling pathway 9/249 103/7206 0.00901860391257 ko05224 Breast cancer 13/249 174/7206 0.00912337441691 ko04014 Ras signaling pathway 18/249 279/7206 0.0106996727447 ko04210 Apoptosis 13/249 180/7206 0.010959466436 ko05222 Small cell lung cancer 8/249 89/7206 0.0114913521434 ko00512 Mucin type O-glycan biosynthesis 4/249 29/7206 0.0167502227745 ko04064 NF-kappa B signaling pathway 8/249 96/7206 0.0175767709384 ko05144 Malaria 5/249 45/7206 0.0187361068941 ko05166 HTLV-I infection 18/249 292/7206 0.0200152474178 ko05206 MicroRNAs in cancer 12/249 177/7206 0.0211940674477 ko04215 Apoptosis - multiple species 5/249 47/7206 0.0222568588552 ko05212 Pancreatic cancer 7/249 83/7206 0.0241539779302 ko05220 Chronic myeloid leukemia 7/249 85/7206 0.0271103574143 ko04657 IL-17 signaling pathway 7/249 87/7206 0.030304171974 ko05133 Pertussis 7/249 87/7206 0.030304171974 ko00540 Lipopolysaccharide biosynthesis 1/249 1/7206 0.0345545378851 ko04310 Wnt signaling pathway 12/249 181/7206 0.0347657165527 ko05145 Toxoplasmosis 9/249 126/7206 0.0414450516413 ko04015 Rap1 signaling pathway 16/249 278/7206 0.0423974499118 ko05321 Inflammatory bowel disease (IBD) 5/249 56/7206 0.0432643037398 ko05012 Parkinson's disease 1/249 155/7206 0.0451604517581 ko05164 Influenza A 11/249 167/7206 0.0483244893939 ko04068 FoxO signaling pathway 11/249 167/7206 0.0483244893939