ko pathway ratio_in_study ratio_in_pop p_value ko04260 Cardiac muscle contraction 26/179 98/7206 2.48801468753e-20 ko05410 Hypertrophic cardiomyopathy (HCM) 25/179 100/7206 6.870651534e-19 ko05414 Dilated cardiomyopathy 24/179 112/7206 1.69933815352e-16 ko04261 Adrenergic signaling in cardiomyocytes 26/179 205/7206 4.15972581595e-12 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 14/179 79/7206 6.23024175023e-09 ko05416 Viral myocarditis 11/179 55/7206 7.56318386765e-08 ko01200 Carbon metabolism 15/179 128/7206 5.37170317341e-07 ko04022 cGMP-PKG signaling pathway 19/179 216/7206 1.4532020658e-06 ko04510 Focal adhesion 20/179 240/7206 1.77243120565e-06 ko04921 Oxytocin signaling pathway 18/179 209/7206 3.78043770914e-06 ko04371 Apelin signaling pathway 16/179 177/7206 7.24370808166e-06 ko04020 Calcium signaling pathway 20/179 265/7206 8.09962156536e-06 ko00020 Citrate cycle (TCA cycle) 7/179 35/7206 1.9379739612e-05 ko04974 Protein digestion and absorption 10/179 96/7206 0.000123585848987 ko04512 ECM-receptor interaction 9/179 79/7206 0.000135720280915 ko00010 Glycolysis / Gluconeogenesis 8/179 74/7206 0.000461159806901 ko00030 Pentose phosphate pathway 5/179 32/7206 0.00104460672584 ko00680 Methane metabolism 5/179 34/7206 0.00138665871381 ko04010 MAPK signaling pathway 17/179 321/7206 0.00276270158702 ko00710 Carbon fixation in photosynthetic organisms 4/179 27/7206 0.00413186269963 ko00500 Starch and sucrose metabolism 4/179 35/7206 0.0105695720984 ko01230 Biosynthesis of amino acids 6/179 85/7206 0.0187232318208 ko00051 Fructose and mannose metabolism 4/179 42/7206 0.0197661025429 ko05144 Malaria 4/179 45/7206 0.0248521679739 ko00620 Pyruvate metabolism 4/179 46/7206 0.0267071302051 ko04922 Glucagon signaling pathway 7/179 128/7206 0.0398113447345 ko00052 Galactose metabolism 3/179 33/7206 0.0476904384058