ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	168/965	423/7206	9.80866196426e-45
ko04724	Glutamatergic synapse	79/965	152/7206	1.33456397213e-30
ko05033	Nicotine addiction	42/965	56/7206	8.5414711815e-26
ko05032	Morphine addiction	58/965	110/7206	4.01518655604e-23
ko04728	Dopaminergic synapse	75/965	185/7206	1.25343221046e-20
ko04727	GABAergic synapse	53/965	110/7206	6.5810227384e-19
ko04713	Circadian entrainment	60/965	136/7206	7.30341825044e-19
ko04725	Cholinergic synapse	64/965	160/7206	2.12498666099e-17
ko04723	Retrograde endocannabinoid signaling	66/965	175/7206	2.30659973731e-16
ko04024	cAMP signaling pathway	89/965	279/7206	3.51204531576e-16
ko04911	Insulin secretion	49/965	117/7206	1.58416942061e-14
ko04726	Serotonergic synapse	52/965	137/7206	2.85778847404e-13
ko04020	Calcium signaling pathway	80/965	265/7206	4.68594286081e-13
ko04721	Synaptic vesicle cycle	36/965	80/7206	3.98655431416e-12
ko04921	Oxytocin signaling pathway	66/965	209/7206	5.95665870088e-12
ko04742	Taste transduction	29/965	61/7206	9.67161224677e-11
ko05031	Amphetamine addiction	35/965	91/7206	1.55115918419e-09
ko04261	Adrenergic signaling in cardiomyocytes	60/965	205/7206	1.828714915e-09
ko04720	Long-term potentiation	36/965	99/7206	5.3840026587e-09
ko03040	Spliceosome	1/965	145/7206	3.79419960357e-08
ko05030	Cocaine addiction	28/965	73/7206	7.27732634701e-08
ko04925	Aldosterone synthesis and secretion	35/965	105/7206	1.11763387694e-07
ko04970	Salivary secretion	32/965	95/7206	2.98184545645e-07
ko04360	Axon guidance	59/965	233/7206	6.6272204073e-07
ko05322	Systemic lupus erythematosus	3/965	151/7206	1.38324296502e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	26/965	74/7206	1.55204333891e-06
ko04514	Cell adhesion molecules (CAMs)	38/965	130/7206	1.56273130217e-06
ko04730	Long-term depression	26/965	78/7206	4.79028291595e-06
ko04010	MAPK signaling pathway	72/965	321/7206	7.12228379975e-06
ko04971	Gastric acid secretion	30/965	98/7206	7.24659618804e-06
ko04070	Phosphatidylinositol signaling system	33/965	112/7206	7.43332064687e-06
ko03013	RNA transport	5/965	166/7206	7.88771418059e-06
ko04072	Phospholipase D signaling pathway	49/965	197/7206	1.02431473533e-05
ko04972	Pancreatic secretion	32/965	111/7206	1.50550133828e-05
ko04022	cGMP-PKG signaling pathway	52/965	216/7206	1.57819054459e-05
ko05168	Herpes simplex infection	7/965	182/7206	2.14058599693e-05
ko05164	Influenza A	7/965	167/7206	0.00011915518147
ko05203	Viral carcinogenesis	17/965	277/7206	0.000137782673221
ko04745	Phototransduction - fly	14/965	38/7206	0.000230288749839
ko04915	Estrogen signaling pathway	33/965	131/7206	0.000233157463037
ko04612	Antigen processing and presentation	1/965	77/7206	0.000308131866579
ko04621	NOD-like receptor signaling pathway	7/965	157/7206	0.000320343011908
ko03008	Ribosome biogenesis in eukaryotes	1/965	79/7206	0.000326239856064
ko04120	Ubiquitin mediated proteolysis	6/965	138/7206	0.000589114483152
ko04141	Protein processing in endoplasmic reticulum	10/965	184/7206	0.000606236771623
ko04540	Gap junction	31/965	128/7206	0.000884420368985
ko04110	Cell cycle	7/965	145/7206	0.00118754062997
ko04260	Cardiac muscle contraction	25/965	98/7206	0.00137721516317
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/965	79/7206	0.00141460461347
ko04750	Inflammatory mediator regulation of TRP channels	29/965	122/7206	0.00176255724627
ko04924	Renin secretion	22/965	86/7206	0.0021035494676
ko04060	Cytokine-cytokine receptor interaction	12/965	191/7206	0.00237429579564
ko04014	Ras signaling pathway	55/965	279/7206	0.00292542752668
ko05169	Epstein-Barr virus infection	14/965	206/7206	0.00345886965133
ko00330	Arginine and proline metabolism	1/965	61/7206	0.00363738835104
ko05162	Measles	6/965	120/7206	0.00416269150727
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/965	59/7206	0.00577107320437
ko04744	Phototransduction	11/965	36/7206	0.00579845205702
ko04626	Plant-pathogen interaction	7/965	18/7206	0.00627543926227
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/965	14/7206	0.0065423616516
ko05231	Choline metabolism in cancer	29/965	134/7206	0.00698150691606
ko04217	Necroptosis	12/965	178/7206	0.00707420355417
ko00280	Valine, leucine and isoleucine degradation	1/965	54/7206	0.0077185473292
ko05205	Proteoglycans in cancer	22/965	271/7206	0.00813604848072
ko04640	Hematopoietic cell lineage	2/965	64/7206	0.00940363457462
ko04630	Jak-STAT signaling pathway	8/965	132/7206	0.00952482249741
ko04918	Thyroid hormone synthesis	20/965	86/7206	0.0104712411801
ko04964	Proximal tubule bicarbonate reclamation	9/965	29/7206	0.0109193914194
ko04146	Peroxisome	4/965	89/7206	0.011109503459
ko04270	Vascular smooth muscle contraction	32/965	154/7206	0.0113365275268
ko04740	Olfactory transduction	19/965	80/7206	0.0119038682506
ko00310	Lysine degradation	3/965	73/7206	0.01472180444
ko04064	NF-kappa B signaling pathway	5/965	96/7206	0.0149080094493
ko05140	Leishmaniasis	3/965	75/7206	0.0153593953401
ko03420	Nucleotide excision repair	1/965	46/7206	0.0166055025439
ko05414	Dilated cardiomyopathy	24/965	112/7206	0.0167686752187
ko00260	Glycine, serine and threonine metabolism	1/965	48/7206	0.0169881980938
ko04916	Melanogenesis	29/965	142/7206	0.0175361395337
ko00562	Inositol phosphate metabolism	20/965	89/7206	0.0176197581103
ko04960	Aldosterone-regulated sodium reabsorption	11/965	41/7206	0.0189939416107
ko04071	Sphingolipid signaling pathway	32/965	162/7206	0.0195905037117
ko03320	PPAR signaling pathway	3/965	69/7206	0.0206879138721
ko03022	Basal transcription factors	1/965	44/7206	0.0245704135666
ko04015	Rap1 signaling pathway	50/965	278/7206	0.0247354299168
ko05144	Malaria	1/965	45/7206	0.0251387027651
ko00071	Fatty acid degradation	1/965	45/7206	0.0251387027651
ko04371	Apelin signaling pathway	34/965	177/7206	0.0252989648055
ko04930	Type II diabetes mellitus	13/965	54/7206	0.0271570078853
ko04610	Complement and coagulation cascades	4/965	79/7206	0.0290829198111
ko00240	Pyrimidine metabolism	7/965	110/7206	0.032804659831
ko04932	Non-alcoholic fatty liver disease (NAFLD)	15/965	182/7206	0.0362644501199
ko04710	Circadian rhythm	11/965	43/7206	0.0386964975548
ko04115	p53 signaling pathway	4/965	74/7206	0.0392767170689
ko00590	Arachidonic acid metabolism	2/965	52/7206	0.0398967612332
ko04923	Regulation of lipolysis in adipocytes	17/965	77/7206	0.0410195017117
ko05161	Hepatitis B	14/965	173/7206	0.0411143660457
ko05034	Alcoholism	43/965	238/7206	0.0413556116422
ko04976	Bile secretion	17/965	80/7206	0.0464533016398