ko pathway ratio_in_study ratio_in_pop p_value ko03030 DNA replication 19/222 38/7206 1.88091454038e-19 ko03040 Spliceosome 32/222 145/7206 3.15808381009e-19 ko04110 Cell cycle 32/222 145/7206 3.15808381009e-19 ko03460 Fanconi anemia pathway 21/222 51/7206 3.59773076897e-19 ko04111 Cell cycle - yeast 26/222 90/7206 6.07180688823e-19 ko04113 Meiosis - yeast 19/222 70/7206 1.4122333364e-13 ko03430 Mismatch repair 12/222 22/7206 2.68249836899e-13 ko03013 RNA transport 26/222 166/7206 4.49176214995e-12 ko03440 Homologous recombination 14/222 41/7206 7.78259785061e-12 ko03420 Nucleotide excision repair 13/222 46/7206 6.56840011239e-10 ko03410 Base excision repair 11/222 38/7206 1.07246260421e-08 ko00240 Pyrimidine metabolism 17/222 110/7206 3.34590098406e-08 ko04114 Oocyte meiosis 18/222 139/7206 2.13719258875e-07 ko04914 Progesterone-mediated oocyte maturation 13/222 104/7206 1.62109904037e-05 ko03008 Ribosome biogenesis in eukaryotes 11/222 79/7206 2.64733494073e-05 ko04120 Ubiquitin mediated proteolysis 14/222 138/7206 8.21004136906e-05 ko03020 RNA polymerase 6/222 29/7206 0.000209445333378 ko03018 RNA degradation 10/222 84/7206 0.000235907619465 ko05166 HTLV-I infection 21/222 292/7206 0.000330564157574 ko04151 PI3K-Akt signaling pathway 2/222 390/7206 0.00072348412251 ko04010 MAPK signaling pathway 1/222 321/7206 0.000740938679236 ko04014 Ras signaling pathway 1/222 279/7206 0.0023239450344 ko04015 Rap1 signaling pathway 1/222 278/7206 0.00232551556832 ko00230 Purine metabolism 14/222 194/7206 0.00257672900998 ko04810 Regulation of actin cytoskeleton 1/222 264/7206 0.00527239066119 ko03015 mRNA surveillance pathway 8/222 93/7206 0.00769127275727 ko04530 Tight junction 1/222 228/7206 0.0104543719966 ko04022 cGMP-PKG signaling pathway 1/222 216/7206 0.0151628069121 ko04115 p53 signaling pathway 6/222 74/7206 0.025987700837 ko05167 Kaposi's sarcoma-associated herpesvirus infection 1/222 191/7206 0.0316554360389 ko04072 Phospholipase D signaling pathway 1/222 197/7206 0.0327269495848 ko03022 Basal transcription factors 4/222 44/7206 0.0455494784751 ko04141 Protein processing in endoplasmic reticulum 1/222 184/7206 0.0470117645674