ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 34/322 191/7206 2.2294801392e-12 ko04621 NOD-like receptor signaling pathway 23/322 157/7206 3.9805648213e-07 ko00643 Styrene degradation 4/322 4/7206 3.91639244055e-06 ko04380 Osteoclast differentiation 18/322 134/7206 2.54217828476e-05 ko04657 IL-17 signaling pathway 14/322 87/7206 2.67296601839e-05 ko00140 Steroid hormone biosynthesis 9/322 41/7206 6.26608413876e-05 ko04668 TNF signaling pathway 16/322 120/7206 7.84946888134e-05 ko05145 Toxoplasmosis 16/322 126/7206 0.000141456833841 ko05160 Hepatitis C 18/322 153/7206 0.000148756838829 ko05164 Influenza A 19/322 167/7206 0.000153083846174 ko04672 Intestinal immune network for IgA production 8/322 37/7206 0.000180487603301 ko04933 AGE-RAGE signaling pathway in diabetic complications 16/322 135/7206 0.000317239440477 ko05140 Leishmaniasis 11/322 75/7206 0.000450463116841 ko00350 Tyrosine metabolism 7/322 33/7206 0.000520937134063 ko04064 NF-kappa B signaling pathway 12/322 96/7206 0.00109874918557 ko00051 Fructose and mannose metabolism 7/322 42/7206 0.00232967010455 ko04512 ECM-receptor interaction 10/322 79/7206 0.00255742303296 ko05321 Inflammatory bowel disease (IBD) 8/322 56/7206 0.00317401169269 ko04658 Th1 and Th2 cell differentiation 11/322 96/7206 0.00352283145652 ko05146 Amoebiasis 11/322 99/7206 0.00447207108764 ko04622 RIG-I-like receptor signaling pathway 8/322 62/7206 0.00599399137629 ko04640 Hematopoietic cell lineage 8/322 64/7206 0.00726551698495 ko04630 Jak-STAT signaling pathway 13/322 132/7206 0.00817875169504 ko04974 Protein digestion and absorption 10/322 96/7206 0.0102794910034 ko00120 Primary bile acid biosynthesis 4/322 20/7206 0.0107422146625 ko05162 Measles 12/322 120/7206 0.0110914818673 ko04062 Chemokine signaling pathway 17/322 201/7206 0.0134550259211 ko00052 Galactose metabolism 5/322 33/7206 0.0146319321218 ko04917 Prolactin signaling pathway 9/322 87/7206 0.0151895289517 ko05133 Pertussis 9/322 87/7206 0.0151895289517 ko05012 Parkinson's disease 1/322 155/7206 0.0157776619749 ko05323 Rheumatoid arthritis 9/322 89/7206 0.0174248575403 ko04931 Insulin resistance 12/322 137/7206 0.0210116209618 ko04120 Ubiquitin mediated proteolysis 1/322 138/7206 0.021512401645 ko04110 Cell cycle 1/322 145/7206 0.0224395433953 ko04976 Bile secretion 8/322 80/7206 0.0258057592607 ko05168 Herpes simplex infection 15/322 182/7206 0.0263430517731 ko05016 Huntington's disease 3/322 215/7206 0.0270402514407 ko00590 Arachidonic acid metabolism 6/322 52/7206 0.0274275001327 ko05230 Central carbon metabolism in cancer 8/322 81/7206 0.0275658455182 ko04623 Cytosolic DNA-sensing pathway 5/322 41/7206 0.0346290683716 ko04550 Signaling pathways regulating pluripotency of stem cells 2/322 165/7206 0.0348212343467 ko04360 Axon guidance 4/322 233/7206 0.0351197298125 ko05161 Hepatitis B 14/322 173/7206 0.0369464308802 ko00565 Ether lipid metabolism 5/322 42/7206 0.037925642514 ko05332 Graft-versus-host disease 3/322 18/7206 0.0438314200952 ko00401 Novobiocin biosynthesis 1/322 1/7206 0.0446849847351 ko05142 Chagas disease (American trypanosomiasis) 11/322 130/7206 0.0484044141869 ko05152 Tuberculosis 14/322 187/7206 0.0486439450421