ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 31/292 191/7206 2.06911190047e-11 ko04621 NOD-like receptor signaling pathway 19/292 157/7206 1.71782978974e-05 ko04657 IL-17 signaling pathway 12/292 87/7206 0.000181739823676 ko00643 Styrene degradation 3/292 4/7206 0.000255601024614 ko00350 Tyrosine metabolism 7/292 33/7206 0.000287473358456 ko04512 ECM-receptor interaction 11/292 79/7206 0.000309438340812 ko04668 TNF signaling pathway 14/292 120/7206 0.000328116313658 ko05164 Influenza A 17/292 167/7206 0.000404732717081 ko05145 Toxoplasmosis 14/292 126/7206 0.000543011937712 ko04672 Intestinal immune network for IgA production 7/292 37/7206 0.00060286873887 ko04380 Osteoclast differentiation 14/292 134/7206 0.00100684723979 ko04933 AGE-RAGE signaling pathway in diabetic complications 14/292 135/7206 0.00108328279233 ko00140 Steroid hormone biosynthesis 7/292 41/7206 0.0011459540437 ko05160 Hepatitis C 15/292 153/7206 0.00129560634214 ko04064 NF-kappa B signaling pathway 11/292 96/7206 0.00164001627093 ko04622 RIG-I-like receptor signaling pathway 8/292 62/7206 0.00332411554817 ko05161 Hepatitis B 15/292 173/7206 0.00501759250153 ko04658 Th1 and Th2 cell differentiation 10/292 96/7206 0.00528801957655 ko05142 Chagas disease (American trypanosomiasis) 12/292 130/7206 0.00627716080999 ko00051 Fructose and mannose metabolism 6/292 42/7206 0.00644640820269 ko00565 Ether lipid metabolism 6/292 42/7206 0.00644640820269 ko05146 Amoebiasis 10/292 99/7206 0.00656769437783 ko00120 Primary bile acid biosynthesis 4/292 20/7206 0.00765205706085 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/292 4/7206 0.00930058206914 ko05140 Leishmaniasis 8/292 75/7206 0.0105552236136 ko04630 Jak-STAT signaling pathway 12/292 132/7206 0.0111157462242 ko04931 Insulin resistance 12/292 137/7206 0.0126975144432 ko04976 Bile secretion 8/292 80/7206 0.015255797811 ko04666 Fc gamma R-mediated phagocytosis 11/292 122/7206 0.0164779478159 ko00590 Arachidonic acid metabolism 6/292 52/7206 0.0178776553257 ko04623 Cytosolic DNA-sensing pathway 5/292 41/7206 0.0239685829608 ko04917 Prolactin signaling pathway 8/292 87/7206 0.0241622562911 ko05133 Pertussis 8/292 87/7206 0.0241622562911 ko05321 Inflammatory bowel disease (IBD) 6/292 56/7206 0.0249471612073 ko04062 Chemokine signaling pathway 15/292 201/7206 0.0265655276344 ko05323 Rheumatoid arthritis 8/292 89/7206 0.0272643071305 ko05222 Small cell lung cancer 8/292 89/7206 0.0272643071305 ko00360 Phenylalanine metabolism 3/292 17/7206 0.0293755282823 ko05162 Measles 10/292 120/7206 0.0300512735077 ko04110 Cell cycle 1/292 145/7206 0.0313316747078 ko04750 Inflammatory mediator regulation of TRP channels 10/292 122/7206 0.0320113338669 ko05322 Systemic lupus erythematosus 1/292 151/7206 0.0329031281631 ko04020 Calcium signaling pathway 18/292 265/7206 0.0366296306135 ko04610 Complement and coagulation cascades 7/292 79/7206 0.0402952665889 ko00401 Novobiocin biosynthesis 1/292 1/7206 0.0405217873995 ko04640 Hematopoietic cell lineage 6/292 64/7206 0.044171152402 ko04510 Focal adhesion 16/292 240/7206 0.0445405829536 ko04120 Ubiquitin mediated proteolysis 1/292 138/7206 0.0458025378348