ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	33/665	56/7206	1.37309046729e-20
ko04721	Synaptic vesicle cycle	38/665	80/7206	4.0783597921e-19
ko04728	Dopaminergic synapse	55/665	185/7206	7.95233857657e-16
ko04724	Glutamatergic synapse	49/665	152/7206	8.93295057387e-16
ko04080	Neuroactive ligand-receptor interaction	89/665	423/7206	2.64159473624e-14
ko04713	Circadian entrainment	40/665	136/7206	1.16656836612e-11
ko05032	Morphine addiction	34/665	110/7206	9.47342057687e-11
ko04723	Retrograde endocannabinoid signaling	44/665	175/7206	3.32277655134e-10
ko04727	GABAergic synapse	33/665	110/7206	4.32952439859e-10
ko04360	Axon guidance	52/665	233/7206	9.61215664606e-10
ko04725	Cholinergic synapse	39/665	160/7206	8.92636932033e-09
ko04514	Cell adhesion molecules (CAMs)	33/665	130/7206	4.43003027239e-08
ko05031	Amphetamine addiction	26/665	91/7206	9.52889527206e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	23/665	74/7206	9.59059505259e-08
ko05030	Cocaine addiction	22/665	73/7206	3.34500142626e-07
ko04911	Insulin secretion	27/665	117/7206	5.46509311889e-06
ko04726	Serotonergic synapse	30/665	137/7206	6.72627349014e-06
ko04024	cAMP signaling pathway	49/665	279/7206	7.26242410641e-06
ko04966	Collecting duct acid secretion	11/665	26/7206	8.0738406694e-06
ko03040	Spliceosome	1/665	145/7206	1.72118007038e-05
ko04060	Cytokine-cytokine receptor interaction	3/665	191/7206	2.00259998577e-05
ko04261	Adrenergic signaling in cardiomyocytes	37/665	205/7206	6.52148089544e-05
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/665	14/7206	0.000106307464993
ko04010	MAPK signaling pathway	50/665	321/7206	0.000225835231319
ko04744	Phototransduction	11/665	36/7206	0.000265802623572
ko04720	Long-term potentiation	21/665	99/7206	0.000279437458471
ko04120	Ubiquitin mediated proteolysis	2/665	138/7206	0.000284287645754
ko05110	Vibrio cholerae infection	15/665	63/7206	0.000466305790427
ko01200	Carbon metabolism	2/665	128/7206	0.000598622273205
ko05120	Epithelial cell signaling in Helicobacter pylori infection	19/665	92/7206	0.000732541580428
ko03013	RNA transport	4/665	166/7206	0.000928118398244
ko05168	Herpes simplex infection	5/665	182/7206	0.00100066636555
ko04145	Phagosome	28/665	162/7206	0.001321929181
ko04730	Long-term depression	16/665	78/7206	0.00222366304063
ko05203	Viral carcinogenesis	12/665	277/7206	0.00281904110297
ko04146	Peroxisome	1/665	89/7206	0.00282112682747
ko04742	Taste transduction	13/665	61/7206	0.00319336019714
ko04970	Salivary secretion	18/665	95/7206	0.00336889094509
ko03018	RNA degradation	1/665	84/7206	0.0064914888007
ko04141	Protein processing in endoplasmic reticulum	7/665	184/7206	0.0064940293051
ko05322	Systemic lupus erythematosus	5/665	151/7206	0.006724683773
ko04921	Oxytocin signaling pathway	31/665	209/7206	0.00726030843891
ko05146	Amoebiasis	2/665	99/7206	0.00776703018144
ko05034	Alcoholism	34/665	238/7206	0.0086576632786
ko04071	Sphingolipid signaling pathway	25/665	162/7206	0.00884116914737
ko03008	Ribosome biogenesis in eukaryotes	1/665	79/7206	0.00930649804185
ko05164	Influenza A	6/665	167/7206	0.00934252963732
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/665	59/7206	0.00995002000643
ko00310	Lysine degradation	1/665	73/7206	0.0131444912254
ko04964	Proximal tubule bicarbonate reclamation	7/665	29/7206	0.0142101975219
ko04014	Ras signaling pathway	38/665	279/7206	0.014668591599
ko04621	NOD-like receptor signaling pathway	6/665	157/7206	0.0166725439112
ko04540	Gap junction	20/665	128/7206	0.0192915374823
ko01230	Biosynthesis of amino acids	2/665	85/7206	0.0222819039341
ko05162	Measles	4/665	120/7206	0.0241931773016
ko05323	Rheumatoid arthritis	15/665	89/7206	0.0242536030478
ko04611	Platelet activation	7/665	163/7206	0.0273289167939
ko04640	Hematopoietic cell lineage	1/665	64/7206	0.0278913985411
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/665	8/7206	0.030780729237
ko05205	Proteoglycans in cancer	15/665	271/7206	0.0318204995464
ko04064	NF-kappa B signaling pathway	3/665	96/7206	0.0325047669286
ko00564	Glycerophospholipid metabolism	3/665	99/7206	0.0334375915599
ko04924	Renin secretion	14/665	86/7206	0.036085956127
ko04662	B cell receptor signaling pathway	14/665	88/7206	0.0393737215993
ko04022	cGMP-PKG signaling pathway	29/665	216/7206	0.0412105635254
ko04211	Longevity regulating pathway	5/665	123/7206	0.0412726371282
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	4/665	15/7206	0.0430649639358
ko04391	Hippo signaling pathway - fly	14/665	90/7206	0.043548879195
ko00240	Pyrimidine metabolism	4/665	110/7206	0.0442025017986
ko05224	Breast cancer	24/665	174/7206	0.0453238561095
ko04950	Maturity onset diabetes of the young	6/665	29/7206	0.0457010478497
ko04915	Estrogen signaling pathway	19/665	131/7206	0.0458693278835
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	13/665	79/7206	0.0467376812967