ko pathway ratio_in_study ratio_in_pop p_value ko04380 Osteoclast differentiation 24/334 134/7206 8.17136469733e-09 ko04060 Cytokine-cytokine receptor interaction 29/334 191/7206 1.13926644921e-08 ko04650 Natural killer cell mediated cytotoxicity 17/334 97/7206 1.78640056346e-06 ko05164 Influenza A 22/334 167/7206 7.98574476634e-06 ko04621 NOD-like receptor signaling pathway 21/334 157/7206 1.01331000004e-05 ko04064 NF-kappa B signaling pathway 15/334 96/7206 3.05449290793e-05 ko05162 Measles 17/334 120/7206 3.38661275146e-05 ko04662 B cell receptor signaling pathway 14/334 88/7206 4.57237444831e-05 ko04611 Platelet activation 20/334 163/7206 5.8687598029e-05 ko04610 Complement and coagulation cascades 13/334 79/7206 5.94240013339e-05 ko00120 Primary bile acid biosynthesis 6/334 20/7206 0.000211361349177 ko04630 Jak-STAT signaling pathway 16/334 132/7206 0.000369509007938 ko04668 TNF signaling pathway 15/334 120/7206 0.000401922248687 ko05140 Leishmaniasis 11/334 75/7206 0.000613406917099 ko04070 Phosphatidylinositol signaling system 14/334 112/7206 0.00062358722165 ko04620 Toll-like receptor signaling pathway 13/334 100/7206 0.000665023688558 ko05321 Inflammatory bowel disease (IBD) 9/334 56/7206 0.000974825421046 ko05150 Staphylococcus aureus infection 7/334 36/7206 0.00112504145296 ko04666 Fc gamma R-mediated phagocytosis 14/334 122/7206 0.00146064685788 ko04217 Necroptosis 18/334 178/7206 0.00164018854245 ko04660 T cell receptor signaling pathway 14/334 124/7206 0.00170907729538 ko04921 Oxytocin signaling pathway 20/334 209/7206 0.00207288378052 ko05340 Primary immunodeficiency 6/334 30/7206 0.00218706044898 ko05160 Hepatitis C 16/334 153/7206 0.00250312216209 ko04664 Fc epsilon RI signaling pathway 10/334 77/7206 0.00275412124213 ko00051 Fructose and mannose metabolism 7/334 42/7206 0.00286440557014 ko04710 Circadian rhythm 7/334 43/7206 0.00328837819828 ko05152 Tuberculosis 18/334 187/7206 0.00379919170632 ko05167 Kaposi's sarcoma-associated herpesvirus infection 18/334 191/7206 0.00424539359411 ko05168 Herpes simplex infection 17/334 182/7206 0.00606937031805 ko05133 Pertussis 10/334 87/7206 0.00667953167801 ko04622 RIG-I-like receptor signaling pathway 8/334 62/7206 0.00743274653121 ko05161 Hepatitis B 16/334 173/7206 0.00867024897434 ko04659 Th17 cell differentiation 11/334 106/7206 0.00972641802636 ko00592 alpha-Linolenic acid metabolism 4/334 19/7206 0.0101041235801 ko05230 Central carbon metabolism in cancer 9/334 81/7206 0.0122012179812 ko04658 Th1 and Th2 cell differentiation 10/334 96/7206 0.0130673375337 ko05131 Shigellosis 9/334 82/7206 0.0131656239499 ko04137 Mitophagy - animal 9/334 82/7206 0.0131656239499 ko04072 Phospholipase D signaling pathway 17/334 197/7206 0.0142330691349 ko03040 Spliceosome 1/334 145/7206 0.0149742101084 ko04110 Cell cycle 1/334 145/7206 0.0149742101084 ko04062 Chemokine signaling pathway 17/334 201/7206 0.0155996364101 ko05145 Toxoplasmosis 12/334 126/7206 0.0160082013061 ko05016 Huntington's disease 3/334 215/7206 0.0193479150072 ko05132 Salmonella infection 10/334 98/7206 0.0242109799586 ko04670 Leukocyte transendothelial migration 13/334 151/7206 0.0287218802505 ko04925 Aldosterone synthesis and secretion 10/334 105/7206 0.0298311677258 ko00190 Oxidative phosphorylation 1/334 127/7206 0.031072002697 ko04623 Cytosolic DNA-sensing pathway 5/334 41/7206 0.0396116088705 ko03320 PPAR signaling pathway 7/334 69/7206 0.0397272503204 ko00983 Drug metabolism - other enzymes 5/334 42/7206 0.0433260711205 ko04141 Protein processing in endoplasmic reticulum 3/334 184/7206 0.0490079144269 ko05012 Parkinson's disease 2/334 155/7206 0.0498129077117