ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 23/141 191/7206 1.51348243361e-12 ko04621 NOD-like receptor signaling pathway 18/141 157/7206 1.12785309675e-09 ko05164 Influenza A 17/141 167/7206 2.09410684015e-08 ko04620 Toll-like receptor signaling pathway 13/141 100/7206 5.86374975907e-08 ko05160 Hepatitis C 15/141 153/7206 2.47364591753e-07 ko04672 Intestinal immune network for IgA production 8/141 37/7206 4.21154635013e-07 ko05168 Herpes simplex infection 16/141 182/7206 4.33869217946e-07 ko05162 Measles 13/141 120/7206 5.17039106629e-07 ko05321 Inflammatory bowel disease (IBD) 9/141 56/7206 1.12929693269e-06 ko04380 Osteoclast differentiation 13/141 134/7206 1.84695083784e-06 ko04622 RIG-I-like receptor signaling pathway 9/141 62/7206 2.73734372983e-06 ko05152 Tuberculosis 15/141 187/7206 3.24714473594e-06 ko05323 Rheumatoid arthritis 10/141 89/7206 8.13597685607e-06 ko04623 Cytosolic DNA-sensing pathway 7/141 41/7206 1.21955950057e-05 ko05140 Leishmaniasis 9/141 75/7206 1.36600868112e-05 ko04064 NF-kappa B signaling pathway 10/141 96/7206 1.60627207767e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 14/141 191/7206 1.98017868411e-05 ko05161 Hepatitis B 13/141 173/7206 3.0601245896e-05 ko05145 Toxoplasmosis 11/141 126/7206 3.23720103941e-05 ko04217 Necroptosis 13/141 178/7206 4.13096334355e-05 ko04933 AGE-RAGE signaling pathway in diabetic complications 11/141 135/7206 6.13663859085e-05 ko04668 TNF signaling pathway 10/141 120/7206 0.00011088557175 ko04610 Complement and coagulation cascades 8/141 79/7206 0.000142457681198 ko04630 Jak-STAT signaling pathway 10/141 132/7206 0.000244243000753 ko04658 Th1 and Th2 cell differentiation 8/141 96/7206 0.000547781994057 ko05133 Pertussis 7/141 87/7206 0.00150007174718 ko05144 Malaria 5/141 45/7206 0.001739604541 ko04062 Chemokine signaling pathway 11/141 201/7206 0.00187459175926 ko05340 Primary immunodeficiency 4/141 30/7206 0.00259235787255 ko04670 Leukocyte transendothelial migration 9/141 151/7206 0.0027344236566 ko05132 Salmonella infection 7/141 98/7206 0.00297289649711 ko05134 Legionellosis 6/141 74/7206 0.00313704433572 ko05146 Amoebiasis 7/141 99/7206 0.00314786494838 ko04612 Antigen processing and presentation 6/141 77/7206 0.00382788515732 ko05142 Chagas disease (American trypanosomiasis) 8/141 130/7206 0.00384892326019 ko04659 Th17 cell differentiation 7/141 106/7206 0.00460293684794 ko05150 Staphylococcus aureus infection 4/141 36/7206 0.00508984599292 ko05212 Pancreatic cancer 6/141 83/7206 0.00554002608411 ko04662 B cell receptor signaling pathway 6/141 88/7206 0.00734813481687 ko04210 Apoptosis 9/141 180/7206 0.00859372498388 ko04660 T cell receptor signaling pathway 7/141 124/7206 0.0106452209772 ko05330 Allograft rejection 3/141 24/7206 0.0109862063675 ko04514 Cell adhesion molecules (CAMs) 7/141 130/7206 0.0135695319192 ko05200 Pathways in cancer 17/141 492/7206 0.018034017026 ko05320 Autoimmune thyroid disease 3/141 29/7206 0.0184771095575 ko05418 Fluid shear stress and atherosclerosis 8/141 173/7206 0.0199174322401 ko05131 Shigellosis 5/141 82/7206 0.0218938872432 ko04917 Prolactin signaling pathway 5/141 87/7206 0.0274590059836 ko05166 HTLV-I infection 11/141 292/7206 0.0303796165251 ko05120 Epithelial cell signaling in Helicobacter pylori infection 5/141 92/7206 0.0338531863307 ko04145 Phagosome 7/141 162/7206 0.039300984072 ko04650 Natural killer cell mediated cytotoxicity 5/141 97/7206 0.0411040470162 ko05310 Asthma 2/141 17/7206 0.0426713887924 ko05332 Graft-versus-host disease 2/141 18/7206 0.0474022551905