ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 32/224 191/7206 2.12437238726e-15 ko05340 Primary immunodeficiency 14/224 30/7206 4.91793842711e-14 ko05152 Tuberculosis 25/224 187/7206 4.89801699808e-10 ko05145 Toxoplasmosis 20/224 126/7206 1.4017893716e-09 ko04380 Osteoclast differentiation 20/224 134/7206 4.25621785875e-09 ko05164 Influenza A 22/224 167/7206 7.61511197757e-09 ko04612 Antigen processing and presentation 15/224 77/7206 9.76986782957e-09 ko05321 Inflammatory bowel disease (IBD) 13/224 56/7206 1.03450035942e-08 ko04659 Th17 cell differentiation 17/224 106/7206 2.15932968886e-08 ko04650 Natural killer cell mediated cytotoxicity 16/224 97/7206 3.77677386697e-08 ko05140 Leishmaniasis 14/224 75/7206 5.46958999856e-08 ko05168 Herpes simplex infection 21/224 182/7206 1.76287569388e-07 ko04658 Th1 and Th2 cell differentiation 15/224 96/7206 2.14272525415e-07 ko04660 T cell receptor signaling pathway 17/224 124/7206 2.32130564452e-07 ko05330 Allograft rejection 8/224 24/7206 3.6832919321e-07 ko05150 Staphylococcus aureus infection 9/224 36/7206 1.04557846832e-06 ko04672 Intestinal immune network for IgA production 9/224 37/7206 1.34468111442e-06 ko05320 Autoimmune thyroid disease 8/224 29/7206 1.87882291207e-06 ko04630 Jak-STAT signaling pathway 16/224 132/7206 2.85001390789e-06 ko05162 Measles 15/224 120/7206 3.99245006955e-06 ko04064 NF-kappa B signaling pathway 13/224 96/7206 7.33720415594e-06 ko04145 Phagosome 17/224 162/7206 1.00967924099e-05 ko05332 Graft-versus-host disease 6/224 18/7206 1.14518811673e-05 ko05323 Rheumatoid arthritis 12/224 89/7206 1.73610101828e-05 ko04666 Fc gamma R-mediated phagocytosis 14/224 122/7206 2.28083450176e-05 ko04621 NOD-like receptor signaling pathway 16/224 157/7206 2.67765885591e-05 ko04610 Complement and coagulation cascades 11/224 79/7206 2.87737953213e-05 ko04620 Toll-like receptor signaling pathway 12/224 100/7206 5.68190446098e-05 ko05133 Pertussis 11/224 87/7206 7.1666452709e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 17/224 191/7206 8.52713957778e-05 ko05310 Asthma 5/224 17/7206 0.00012650180759 ko04640 Hematopoietic cell lineage 9/224 64/7206 0.000143416355441 ko04062 Chemokine signaling pathway 17/224 201/7206 0.000159890461003 ko04940 Type I diabetes mellitus 6/224 32/7206 0.000388093043133 ko05144 Malaria 7/224 45/7206 0.000423197546903 ko04664 Fc epsilon RI signaling pathway 9/224 77/7206 0.000591998685928 ko05142 Chagas disease (American trypanosomiasis) 12/224 130/7206 0.000686120374019 ko05132 Salmonella infection 10/224 98/7206 0.000880920291477 ko05161 Hepatitis B 14/224 173/7206 0.000942565160982 ko04217 Necroptosis 14/224 178/7206 0.00124370271853 ko03050 Proteasome 7/224 54/7206 0.00130320612465 ko05416 Viral myocarditis 7/224 55/7206 0.00145454417092 ko04662 B cell receptor signaling pathway 9/224 88/7206 0.00156069813481 ko04611 Platelet activation 13/224 163/7206 0.00162849090688 ko04622 RIG-I-like receptor signaling pathway 7/224 62/7206 0.00293399556257 ko05131 Shigellosis 8/224 82/7206 0.00379078833056 ko04514 Cell adhesion molecules (CAMs) 10/224 130/7206 0.00707939040075 ko05160 Hepatitis C 11/224 153/7206 0.00795655003334 ko04623 Cytosolic DNA-sensing pathway 5/224 41/7206 0.00835640229558 ko04360 Axon guidance 1/224 233/7206 0.0107972392433 ko00120 Primary bile acid biosynthesis 3/224 20/7206 0.0228625434241 ko00966 Glucosinolate biosynthesis 1/224 1/7206 0.0310852067722 ko04728 Dopaminergic synapse 1/224 185/7206 0.0315170929957 ko04668 TNF signaling pathway 8/224 120/7206 0.0329619946401 ko05146 Amoebiasis 7/224 99/7206 0.0340192563101 ko04723 Retrograde endocannabinoid signaling 1/224 175/7206 0.0453504382762 ko04310 Wnt signaling pathway 1/224 181/7206 0.0465409220308