ko pathway ratio_in_study ratio_in_pop p_value ko04721 Synaptic vesicle cycle 12/117 80/7206 4.52068356858e-09 ko04728 Dopaminergic synapse 16/117 185/7206 3.88409449678e-08 ko05033 Nicotine addiction 7/117 56/7206 2.98451252081e-05 ko04724 Glutamatergic synapse 10/117 152/7206 0.000167473059078 ko04514 Cell adhesion molecules (CAMs) 9/117 130/7206 0.000244894582094 ko04713 Circadian entrainment 9/117 136/7206 0.000343249315558 ko05031 Amphetamine addiction 7/117 91/7206 0.000652605534605 ko04915 Estrogen signaling pathway 8/117 131/7206 0.00124853926456 ko04360 Axon guidance 11/117 233/7206 0.0013515386493 ko04010 MAPK signaling pathway 13/117 321/7206 0.00201336709301 ko04723 Retrograde endocannabinoid signaling 9/117 175/7206 0.00208356504586 ko04024 cAMP signaling pathway 11/117 279/7206 0.005461760152 ko04261 Adrenergic signaling in cardiomyocytes 9/117 205/7206 0.00595893639109 ko04921 Oxytocin signaling pathway 9/117 209/7206 0.00674268870474 ko04727 GABAergic synapse 6/117 110/7206 0.0087724820571 ko05032 Morphine addiction 6/117 110/7206 0.0087724820571 ko05142 Chagas disease (American trypanosomiasis) 6/117 130/7206 0.0188394283839 ko00604 Glycosphingolipid biosynthesis - ganglio series 2/117 14/7206 0.0209403334839 ko05231 Choline metabolism in cancer 6/117 134/7206 0.0215327708965 ko05030 Cocaine addiction 4/117 73/7206 0.0304785172656 ko05014 Amyotrophic lateral sclerosis (ALS) 4/117 74/7206 0.0318289945003 ko04130 SNARE interactions in vesicular transport 3/117 44/7206 0.0341138197423 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 4/117 79/7206 0.0391043964879 ko04911 Insulin secretion 5/117 117/7206 0.0412846596217 ko04725 Cholinergic synapse 6/117 160/7206 0.0454857381284