ko pathway ratio_in_study ratio_in_pop p_value ko04360 Axon guidance 34/370 233/7206 2.34671214868e-08 ko04950 Maturity onset diabetes of the young 11/370 29/7206 8.46220668334e-08 ko04514 Cell adhesion molecules (CAMs) 21/370 130/7206 2.37621024055e-06 ko04721 Synaptic vesicle cycle 15/370 80/7206 1.06410147332e-05 ko04911 Insulin secretion 18/370 117/7206 2.50503357481e-05 ko04391 Hippo signaling pathway - fly 15/370 90/7206 4.58798392744e-05 ko05033 Nicotine addiction 11/370 56/7206 0.000103916071028 ko05217 Basal cell carcinoma 12/370 68/7206 0.000150201212415 ko04512 ECM-receptor interaction 13/370 79/7206 0.000167791630046 ko04974 Protein digestion and absorption 14/370 96/7206 0.000352940541341 ko04728 Dopaminergic synapse 21/370 185/7206 0.000541272394936 ko04340 Hedgehog signaling pathway 10/370 58/7206 0.000644362134073 ko05224 Breast cancer 20/370 174/7206 0.00065811213193 ko05168 Herpes simplex infection 1/370 182/7206 0.00106109915208 ko04010 MAPK signaling pathway 30/370 321/7206 0.00163015370169 ko04961 Endocrine and other factor-regulated calcium reabsorption 9/370 59/7206 0.00288872861017 ko03013 RNA transport 1/370 166/7206 0.00351449997771 ko05200 Pathways in cancer 40/370 492/7206 0.00397618356883 ko04330 Notch signaling pathway 9/370 62/7206 0.00407359632118 ko04151 PI3K-Akt signaling pathway 33/370 390/7206 0.00429163543298 ko00230 Purine metabolism 2/370 194/7206 0.00437625875023 ko05322 Systemic lupus erythematosus 1/370 151/7206 0.00481149966499 ko04141 Protein processing in endoplasmic reticulum 2/370 184/7206 0.00615480804276 ko05203 Viral carcinogenesis 5/370 277/7206 0.00762180258428 ko04217 Necroptosis 2/370 178/7206 0.00883124458283 ko04120 Ubiquitin mediated proteolysis 1/370 138/7206 0.010183716887 ko04145 Phagosome 16/370 162/7206 0.0105643622063 ko04390 Hippo signaling pathway 18/370 188/7206 0.0105912129649 ko04550 Signaling pathways regulating pluripotency of stem cells 16/370 165/7206 0.0119401993111 ko05014 Amyotrophic lateral sclerosis (ALS) 9/370 74/7206 0.0129518966009 ko04723 Retrograde endocannabinoid signaling 17/370 175/7206 0.0133192753292 ko04727 GABAergic synapse 12/370 110/7206 0.0133575643254 ko04724 Glutamatergic synapse 15/370 152/7206 0.0139431150913 ko04611 Platelet activation 2/370 163/7206 0.0177855631059 ko04211 Longevity regulating pathway 1/370 123/7206 0.0214030128159 ko00190 Oxidative phosphorylation 1/370 127/7206 0.0224333812342 ko04261 Adrenergic signaling in cardiomyocytes 18/370 205/7206 0.0233980812001 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/370 182/7206 0.0258396038227 ko04150 mTOR signaling pathway 3/370 184/7206 0.0260804959112 ko05016 Huntington's disease 4/370 215/7206 0.0262779001479 ko05202 Transcriptional misregulation in cancer 17/370 188/7206 0.0271001471277 ko05032 Morphine addiction 11/370 110/7206 0.028057369495 ko04070 Phosphatidylinositol signaling system 1/370 112/7206 0.0306345117411 ko00604 Glycosphingolipid biosynthesis - ganglio series 3/370 14/7206 0.0320346635063 ko05161 Hepatitis B 3/370 173/7206 0.035460508483 ko04341 Hedgehog signaling pathway - fly 5/370 38/7206 0.0432837793258 ko04725 Cholinergic synapse 14/370 160/7206 0.0447565723665 ko05164 Influenza A 3/370 167/7206 0.048886169437