ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	62/544	152/7206	5.27323620516e-31
ko04080	Neuroactive ligand-receptor interaction	101/544	423/7206	1.54839366837e-27
ko05033	Nicotine addiction	32/544	56/7206	4.07324674002e-22
ko04728	Dopaminergic synapse	53/544	185/7206	2.41189542814e-18
ko04727	GABAergic synapse	37/544	110/7206	1.32414585265e-15
ko04713	Circadian entrainment	41/544	136/7206	2.8520651936e-15
ko04721	Synaptic vesicle cycle	31/544	80/7206	3.0952744455e-15
ko04723	Retrograde endocannabinoid signaling	47/544	175/7206	3.55534432047e-15
ko05032	Morphine addiction	35/544	110/7206	5.41714731635e-14
ko04024	cAMP signaling pathway	57/544	279/7206	1.47833751129e-12
ko05031	Amphetamine addiction	27/544	91/7206	2.67951858113e-10
ko04726	Serotonergic synapse	34/544	137/7206	2.79611034021e-10
ko05030	Cocaine addiction	23/544	73/7206	1.55954139438e-09
ko04725	Cholinergic synapse	35/544	160/7206	5.79762379762e-09
ko04911	Insulin secretion	29/544	117/7206	6.1040935945e-09
ko04514	Cell adhesion molecules (CAMs)	30/544	130/7206	1.99539880011e-08
ko04020	Calcium signaling pathway	45/544	265/7206	1.66974694732e-07
ko04921	Oxytocin signaling pathway	38/544	209/7206	3.04769899558e-07
ko04261	Adrenergic signaling in cardiomyocytes	37/544	205/7206	5.11877301487e-07
ko04010	MAPK signaling pathway	50/544	321/7206	6.58479540423e-07
ko04720	Long-term potentiation	22/544	99/7206	3.10907124875e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	18/544	74/7206	6.41704255751e-06
ko04742	Taste transduction	16/544	61/7206	7.40408749496e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/544	79/7206	1.70203353508e-05
ko04260	Cardiac muscle contraction	20/544	98/7206	3.30414054595e-05
ko05203	Viral carcinogenesis	6/544	277/7206	0.000111726750522
ko04730	Long-term depression	16/544	78/7206	0.000188229888005
ko05205	Proteoglycans in cancer	6/544	271/7206	0.000226230069089
ko05164	Influenza A	2/544	167/7206	0.000311683085965
ko04970	Salivary secretion	17/544	95/7206	0.000655140774724
ko05162	Measles	1/544	120/7206	0.00141358516172
ko04972	Pancreatic secretion	18/544	111/7206	0.0016713869798
ko04060	Cytokine-cytokine receptor interaction	4/544	191/7206	0.00192991858916
ko04930	Type II diabetes mellitus	11/544	54/7206	0.00198167355428
ko04360	Axon guidance	31/544	233/7206	0.0021768696095
ko04022	cGMP-PKG signaling pathway	29/544	216/7206	0.00230778166458
ko05168	Herpes simplex infection	4/544	182/7206	0.00260674446271
ko04120	Ubiquitin mediated proteolysis	2/544	138/7206	0.00285764263601
ko00240	Pyrimidine metabolism	1/544	110/7206	0.00304771724918
ko04630	Jak-STAT signaling pathway	2/544	132/7206	0.00405640577949
ko04350	TGF-beta signaling pathway	1/544	103/7206	0.00443782055929
ko05322	Systemic lupus erythematosus	3/544	151/7206	0.00465432109188
ko04964	Proximal tubule bicarbonate reclamation	7/544	29/7206	0.00485064182507
ko04014	Ras signaling pathway	34/544	279/7206	0.00516282762469
ko04072	Phospholipase D signaling pathway	26/544	197/7206	0.00557864873894
ko05414	Dilated cardiomyopathy	17/544	112/7206	0.00560181307443
ko04915	Estrogen signaling pathway	19/544	131/7206	0.00641880999558
ko05034	Alcoholism	29/544	238/7206	0.00864669320614
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/544	182/7206	0.00976379497881
ko04140	Autophagy - animal	4/544	164/7206	0.00995906108488
ko05410	Hypertrophic cardiomyopathy (HCM)	15/544	100/7206	0.0110813074262
ko04961	Endocrine and other factor-regulated calcium reabsorption	10/544	59/7206	0.0120037066152
ko04621	NOD-like receptor signaling pathway	4/544	157/7206	0.0133952567841
ko05010	Alzheimer's disease	25/544	202/7206	0.0140635387347
ko04925	Aldosterone synthesis and secretion	15/544	105/7206	0.0142890594463
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/544	14/7206	0.0174689292089
ko04971	Gastric acid secretion	14/544	98/7206	0.0187426813099
ko04137	Mitophagy - animal	1/544	82/7206	0.0199732338788
ko04141	Protein processing in endoplasmic reticulum	6/544	184/7206	0.022800668218
ko04611	Platelet activation	5/544	163/7206	0.0238656947806
ko04550	Signaling pathways regulating pluripotency of stem cells	5/544	165/7206	0.0240832930642
ko03013	RNA transport	5/544	166/7206	0.0242991019075
ko04110	Cell cycle	4/544	145/7206	0.0247928622658
ko05110	Vibrio cholerae infection	10/544	63/7206	0.0256090184363
ko04540	Gap junction	17/544	128/7206	0.0258667835136
ko04070	Phosphatidylinositol signaling system	15/544	112/7206	0.0281564286805
ko04612	Antigen processing and presentation	1/544	77/7206	0.0289755257186
ko03008	Ribosome biogenesis in eukaryotes	1/544	79/7206	0.0294278722932
ko04217	Necroptosis	6/544	178/7206	0.0302261925737
ko04973	Carbohydrate digestion and absorption	7/544	42/7206	0.0359431076329
ko00515	Mannose type O-glycan biosynthesis	5/544	25/7206	0.0362004288607
ko04924	Renin secretion	12/544	86/7206	0.0363367394339
ko05161	Hepatitis B	6/544	173/7206	0.040077483435
ko04214	Apoptosis - fly	1/544	72/7206	0.041985490289
ko04966	Collecting duct acid secretion	5/544	26/7206	0.0421383240812
ko00310	Lysine degradation	1/544	73/7206	0.0422783254157
ko05169	Epstein-Barr virus infection	8/544	206/7206	0.0437561716295
ko04510	Focal adhesion	10/544	240/7206	0.0457359900941
ko05215	Prostate cancer	3/544	111/7206	0.0465171595344
ko04150	mTOR signaling pathway	7/544	184/7206	0.0479679345825