ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	194/1207	423/7206	1.16881252684e-47
ko04724	Glutamatergic synapse	92/1207	152/7206	1.03063795691e-34
ko05033	Nicotine addiction	47/1207	56/7206	2.53446205929e-28
ko05032	Morphine addiction	67/1207	110/7206	9.68259363703e-26
ko04727	GABAergic synapse	66/1207	110/7206	7.73806018712e-25
ko04713	Circadian entrainment	74/1207	136/7206	4.87550942658e-24
ko04721	Synaptic vesicle cycle	51/1207	80/7206	3.79370268331e-21
ko04728	Dopaminergic synapse	85/1207	185/7206	5.51278595352e-21
ko04725	Cholinergic synapse	74/1207	160/7206	1.32059418563e-18
ko04723	Retrograde endocannabinoid signaling	78/1207	175/7206	2.29713625398e-18
ko04911	Insulin secretion	57/1207	117/7206	7.21171070388e-16
ko04742	Taste transduction	38/1207	61/7206	1.39706551726e-15
ko04020	Calcium signaling pathway	97/1207	265/7206	1.74000012296e-15
ko04024	cAMP signaling pathway	100/1207	279/7206	4.07491036101e-15
ko04726	Serotonergic synapse	60/1207	137/7206	5.66920393309e-14
ko04921	Oxytocin signaling pathway	79/1207	209/7206	1.18297759287e-13
ko04744	Phototransduction	24/1207	36/7206	3.1219822421e-11
ko05031	Amphetamine addiction	42/1207	91/7206	4.61079337219e-11
ko04720	Long-term potentiation	44/1207	99/7206	7.54718147451e-11
ko04970	Salivary secretion	41/1207	95/7206	1.00882647192e-09
ko03040	Spliceosome	2/1207	145/7206	1.56398282029e-09
ko03010	Ribosome	1/1207	129/7206	2.60363762462e-09
ko04261	Adrenergic signaling in cardiomyocytes	68/1207	205/7206	5.70004879597e-09
ko05168	Herpes simplex infection	7/1207	182/7206	9.27911176391e-08
ko05203	Viral carcinogenesis	17/1207	277/7206	1.10139982969e-07
ko04925	Aldosterone synthesis and secretion	40/1207	105/7206	1.14980587839e-07
ko04740	Olfactory transduction	33/1207	80/7206	1.62270301331e-07
ko05322	Systemic lupus erythematosus	5/1207	151/7206	3.85960397501e-07
ko04022	cGMP-PKG signaling pathway	65/1207	216/7206	7.04850102205e-07
ko04971	Gastric acid secretion	37/1207	98/7206	7.22860436832e-07
ko04966	Collecting duct acid secretion	15/1207	26/7206	2.58525681919e-06
ko05030	Cocaine addiction	29/1207	73/7206	3.7261801947e-06
ko04621	NOD-like receptor signaling pathway	7/1207	157/7206	3.76762205571e-06
ko04360	Axon guidance	67/1207	233/7206	4.10221912087e-06
ko03013	RNA transport	8/1207	166/7206	4.23553919664e-06
ko04060	Cytokine-cytokine receptor interaction	11/1207	191/7206	7.37051154356e-06
ko04730	Long-term depression	29/1207	78/7206	1.13427551598e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	28/1207	74/7206	1.15465461921e-05
ko05164	Influenza A	9/1207	167/7206	1.29828647153e-05
ko04110	Cell cycle	7/1207	145/7206	1.55191294415e-05
ko04972	Pancreatic secretion	37/1207	111/7206	1.5885888414e-05
ko04514	Cell adhesion molecules (CAMs)	41/1207	130/7206	2.54189295793e-05
ko04120	Ubiquitin mediated proteolysis	7/1207	138/7206	4.45673812087e-05
ko04010	MAPK signaling pathway	82/1207	321/7206	4.5012209953e-05
ko04141	Protein processing in endoplasmic reticulum	12/1207	184/7206	5.21371189641e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1207	79/7206	0.00011049557844
ko05161	Hepatitis B	12/1207	173/7206	0.000181364255461
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	27/1207	79/7206	0.000186217642335
ko04745	Phototransduction - fly	16/1207	38/7206	0.000193637868894
ko04540	Gap junction	38/1207	128/7206	0.000275400114911
ko04976	Bile secretion	26/1207	80/7206	0.000448316936813
ko04072	Phospholipase D signaling pathway	52/1207	197/7206	0.000468929412356
ko05110	Vibrio cholerae infection	22/1207	63/7206	0.000475664937938
ko04750	Inflammatory mediator regulation of TRP channels	36/1207	122/7206	0.000513385746381
ko04260	Cardiac muscle contraction	30/1207	98/7206	0.000569941442266
ko05169	Epstein-Barr virus infection	17/1207	206/7206	0.00059132554402
ko04610	Complement and coagulation cascades	3/1207	79/7206	0.000694820970019
ko05414	Dilated cardiomyopathy	33/1207	112/7206	0.000771529548759
ko04070	Phosphatidylinositol signaling system	33/1207	112/7206	0.000771529548759
ko00520	Amino sugar and nucleotide sugar metabolism	1/1207	55/7206	0.000836898835517
ko04014	Ras signaling pathway	68/1207	279/7206	0.00100709868239
ko04612	Antigen processing and presentation	3/1207	77/7206	0.0010254142373
ko04961	Endocrine and other factor-regulated calcium reabsorption	20/1207	59/7206	0.00123467276181
ko04064	NF-kappa B signaling pathway	5/1207	96/7206	0.00130313150495
ko04630	Jak-STAT signaling pathway	9/1207	132/7206	0.00131645508522
ko04964	Proximal tubule bicarbonate reclamation	12/1207	29/7206	0.00146605113699
ko04371	Apelin signaling pathway	46/1207	177/7206	0.00150140661433
ko05140	Leishmaniasis	3/1207	75/7206	0.00152108452084
ko04330	Notch signaling pathway	2/1207	62/7206	0.00175922935832
ko05162	Measles	8/1207	120/7206	0.00182948216853
ko04214	Apoptosis - fly	3/1207	72/7206	0.0021587384698
ko04146	Peroxisome	5/1207	89/7206	0.00248458734104
ko05205	Proteoglycans in cancer	28/1207	271/7206	0.0027991335645
ko04710	Circadian rhythm	15/1207	43/7206	0.00337038794216
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/1207	14/7206	0.00419083387436
ko04915	Estrogen signaling pathway	35/1207	131/7206	0.0042266283635
ko03420	Nucleotide excision repair	1/1207	46/7206	0.00446617269236
ko04924	Renin secretion	25/1207	86/7206	0.00512174094066
ko04626	Plant-pathogen interaction	8/1207	18/7206	0.00544929626818
ko04210	Apoptosis	17/1207	180/7206	0.0061760289042
ko05166	HTLV-I infection	32/1207	292/7206	0.00634372408057
ko05131	Shigellosis	5/1207	82/7206	0.00684185086332
ko03022	Basal transcription factors	1/1207	44/7206	0.00689652264893
ko00590	Arachidonic acid metabolism	2/1207	52/7206	0.00818133098638
ko04923	Regulation of lipolysis in adipocytes	22/1207	77/7206	0.00850126570722
ko04930	Type II diabetes mellitus	17/1207	54/7206	0.00892316129326
ko04622	RIG-I-like receptor signaling pathway	3/1207	62/7206	0.00927721666049
ko04668	TNF signaling pathway	10/1207	120/7206	0.00955561221782
ko05410	Hypertrophic cardiomyopathy (HCM)	27/1207	100/7206	0.00968131549503
ko04932	Non-alcoholic fatty liver disease (NAFLD)	18/1207	182/7206	0.011550382974
ko04270	Vascular smooth muscle contraction	38/1207	154/7206	0.0116232874768
ko04657	IL-17 signaling pathway	6/1207	87/7206	0.0130330206688
ko05133	Pertussis	6/1207	87/7206	0.0130330206688
ko00240	Pyrimidine metabolism	9/1207	110/7206	0.0138555538762
ko05145	Toxoplasmosis	11/1207	126/7206	0.0153379337646
ko04916	Melanogenesis	35/1207	142/7206	0.0164722358337
ko05219	Bladder cancer	2/1207	48/7206	0.0178720719603
ko00310	Lysine degradation	5/1207	73/7206	0.018064290089
ko04115	p53 signaling pathway	5/1207	74/7206	0.0180815244336
ko04960	Aldosterone-regulated sodium reabsorption	13/1207	41/7206	0.0184179664216
ko05321	Inflammatory bowel disease (IBD)	3/1207	56/7206	0.0184602298461
ko04973	Carbohydrate digestion and absorption	13/1207	42/7206	0.0208025375148
ko05222	Small cell lung cancer	7/1207	89/7206	0.021674255077
ko05144	Malaria	2/1207	45/7206	0.0254712790594
ko00071	Fatty acid degradation	2/1207	45/7206	0.0254712790594
ko00280	Valine, leucine and isoleucine degradation	3/1207	54/7206	0.0264005521013
ko04658	Th1 and Th2 cell differentiation	8/1207	96/7206	0.0266804220079
ko04912	GnRH signaling pathway	30/1207	122/7206	0.0268222965615
ko05215	Prostate cancer	10/1207	111/7206	0.0285489516835
ko04114	Oocyte meiosis	33/1207	139/7206	0.0293847733473
ko04922	Glucagon signaling pathway	31/1207	128/7206	0.0306442063764
ko05206	MicroRNAs in cancer	19/1207	177/7206	0.0317460055617
ko04350	TGF-beta signaling pathway	9/1207	103/7206	0.0322153194663
ko04015	Rap1 signaling pathway	60/1207	278/7206	0.0328765801415
ko00860	Porphyrin and chlorophyll metabolism	1/1207	34/7206	0.0342779916038
ko03018	RNA degradation	7/1207	84/7206	0.0386757139529
ko05200	Pathways in cancer	66/1207	492/7206	0.0391170467608
ko05220	Chronic myeloid leukemia	7/1207	85/7206	0.0392467411794
ko04213	Longevity regulating pathway - multiple species	22/1207	86/7206	0.0402899072068
ko04918	Thyroid hormone synthesis	22/1207	86/7206	0.0402899072068
ko04620	Toll-like receptor signaling pathway	9/1207	100/7206	0.0417713806644
ko01524	Platinum drug resistance	6/1207	76/7206	0.042970580458
ko00512	Mucin type O-glycan biosynthesis	9/1207	29/7206	0.0470121134267
ko05340	Primary immunodeficiency	1/1207	30/7206	0.0486680612182