ko pathway ratio_in_study ratio_in_pop p_value ko04925 Aldosterone synthesis and secretion 3/12 105/7206 0.000601102880868 ko04911 Insulin secretion 3/12 117/7206 0.000824745050432 ko04912 GnRH signaling pathway 3/12 122/7206 0.000931660025836 ko04540 Gap junction 3/12 128/7206 0.0010711695577 ko04270 Vascular smooth muscle contraction 3/12 154/7206 0.00182757370908 ko04725 Cholinergic synapse 3/12 160/7206 0.00203954262698 ko04962 Vasopressin-regulated water reabsorption 2/12 58/7206 0.00399033664592 ko04961 Endocrine and other factor-regulated calcium reabsorption 2/12 59/7206 0.00412652902493 ko04913 Ovarian steroidogenesis 2/12 63/7206 0.0046927783763 ko05110 Vibrio cholerae infection 2/12 63/7206 0.0046927783763 ko04923 Regulation of lipolysis in adipocytes 2/12 77/7206 0.00694029726985 ko04976 Bile secretion 2/12 80/7206 0.00747456359588 ko04020 Calcium signaling pathway 3/12 265/7206 0.0084527871692 ko04213 Longevity regulating pathway - multiple species 2/12 86/7206 0.00859758209286 ko04918 Thyroid hormone synthesis 2/12 86/7206 0.00859758209286 ko04014 Ras signaling pathway 3/12 279/7206 0.00973987557446 ko04970 Salivary secretion 2/12 95/7206 0.0104158843483 ko04971 Gastric acid secretion 2/12 98/7206 0.0110570142098 ko05146 Amoebiasis 2/12 99/7206 0.0112745650766 ko04914 Progesterone-mediated oocyte maturation 2/12 104/7206 0.0123908626825 ko01521 EGFR tyrosine kinase inhibitor resistance 2/12 106/7206 0.0128505931694 ko04727 GABAergic synapse 2/12 110/7206 0.0137924474964 ko05032 Morphine addiction 2/12 110/7206 0.0137924474964 ko04010 MAPK signaling pathway 3/12 321/7206 0.0142738567539 ko05414 Dilated cardiomyopathy 2/12 112/7206 0.0142744792565 ko04750 Inflammatory mediator regulation of TRP channels 2/12 122/7206 0.0167938585953 ko04211 Longevity regulating pathway 2/12 123/7206 0.0170556735871 ko01522 Endocrine resistance 2/12 124/7206 0.0173192619346 ko04915 Estrogen signaling pathway 2/12 131/7206 0.0192135668199 ko04713 Circadian entrainment 2/12 136/7206 0.0206186229483 ko04114 Oocyte meiosis 2/12 139/7206 0.0214821200822 ko04916 Melanogenesis 2/12 142/7206 0.0223607854521 ko04724 Glutamatergic synapse 2/12 152/7206 0.0253973537917 ko04611 Platelet activation 2/12 163/7206 0.0289240211958 ko04723 Retrograde endocannabinoid signaling 2/12 175/7206 0.0329861446017 ko04371 Apelin signaling pathway 2/12 177/7206 0.0336843640333 ko04072 Phospholipase D signaling pathway 2/12 197/7206 0.0409872002779 ko04062 Chemokine signaling pathway 2/12 201/7206 0.042515682765 ko05200 Pathways in cancer 3/12 492/7206 0.0438021578856 ko04261 Adrenergic signaling in cardiomyocytes 2/12 205/7206 0.0440660813954 ko04921 Oxytocin signaling pathway 2/12 209/7206 0.0456380916506 ko04022 cGMP-PKG signaling pathway 2/12 216/7206 0.0484402055074