ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	80/694	145/7206	2.75566352662e-44
ko04110	Cell cycle	62/694	145/7206	2.47818670154e-26
ko03440	Homologous recombination	29/694	41/7206	5.03071236163e-21
ko03008	Ribosome biogenesis in eukaryotes	40/694	79/7206	1.1082486155e-20
ko03460	Fanconi anemia pathway	32/694	51/7206	1.26938317074e-20
ko04111	Cell cycle - yeast	42/694	90/7206	6.3374253855e-20
ko03030	DNA replication	27/694	38/7206	9.76353804112e-20
ko03013	RNA transport	58/694	166/7206	1.70022218137e-19
ko03420	Nucleotide excision repair	25/694	46/7206	2.5443914296e-14
ko04113	Meiosis - yeast	31/694	70/7206	3.09577258398e-14
ko05322	Systemic lupus erythematosus	47/694	151/7206	8.14806088506e-14
ko03430	Mismatch repair	16/694	22/7206	1.99983264974e-12
ko03022	Basal transcription factors	20/694	44/7206	6.86196458335e-10
ko00240	Pyrimidine metabolism	33/694	110/7206	1.31739742351e-09
ko03410	Base excision repair	18/694	38/7206	2.16477601305e-09
ko04144	Endocytosis	6/694	342/7206	2.9308282207e-09
ko05203	Viral carcinogenesis	58/694	277/7206	8.00101486923e-09
ko03018	RNA degradation	27/694	84/7206	8.13628578098e-09
ko05034	Alcoholism	50/694	238/7206	7.16760403781e-08
ko04024	cAMP signaling pathway	5/694	279/7206	1.34367381301e-07
ko03015	mRNA surveillance pathway	25/694	93/7206	1.34975779603e-06
ko04151	PI3K-Akt signaling pathway	13/694	390/7206	1.48957749333e-06
ko03450	Non-homologous end-joining	9/694	15/7206	1.9911201911e-06
ko04724	Glutamatergic synapse	1/694	152/7206	5.00652945495e-06
ko04270	Vascular smooth muscle contraction	1/694	154/7206	5.18263753632e-06
ko04022	cGMP-PKG signaling pathway	4/694	216/7206	5.92192944814e-06
ko03020	RNA polymerase	12/694	29/7206	6.42937440642e-06
ko04060	Cytokine-cytokine receptor interaction	3/694	191/7206	9.15076724622e-06
ko04261	Adrenergic signaling in cardiomyocytes	4/694	205/7206	1.81218106258e-05
ko04713	Circadian entrainment	1/694	136/7206	2.48719191761e-05
ko05010	Alzheimer's disease	4/694	202/7206	2.6953168605e-05
ko04723	Retrograde endocannabinoid signaling	3/694	175/7206	4.10261062495e-05
ko04810	Regulation of actin cytoskeleton	8/694	264/7206	4.3373187755e-05
ko00190	Oxidative phosphorylation	1/694	127/7206	5.4922018052e-05
ko04921	Oxytocin signaling pathway	5/694	209/7206	6.47237404105e-05
ko04510	Focal adhesion	7/694	240/7206	7.89362199909e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/694	182/7206	0.000106805526753
ko04728	Dopaminergic synapse	4/694	185/7206	0.000112988299698
ko04062	Chemokine signaling pathway	5/694	201/7206	0.00013136263268
ko04914	Progesterone-mediated oocyte maturation	23/694	104/7206	0.000131462915925
ko04015	Rap1 signaling pathway	10/694	278/7206	0.000163550750293
ko04014	Ras signaling pathway	10/694	279/7206	0.000165221550641
ko04621	NOD-like receptor signaling pathway	3/694	157/7206	0.00017630548273
ko04725	Cholinergic synapse	3/694	160/7206	0.000186608582197
ko04911	Insulin secretion	1/694	117/7206	0.000186852514624
ko04010	MAPK signaling pathway	13/694	321/7206	0.000206736209963
ko04218	Cellular senescence	33/694	177/7206	0.000232981053467
ko05012	Parkinson's disease	3/694	155/7206	0.000262129085497
ko04727	GABAergic synapse	1/694	110/7206	0.000267133001706
ko05032	Morphine addiction	1/694	110/7206	0.000267133001706
ko05414	Dilated cardiomyopathy	1/694	112/7206	0.000270826788279
ko04114	Oocyte meiosis	27/694	139/7206	0.000369441014894
ko04514	Cell adhesion molecules (CAMs)	2/694	130/7206	0.00041782023865
ko04371	Apelin signaling pathway	5/694	177/7206	0.000685963191658
ko04971	Gastric acid secretion	1/694	98/7206	0.000863773885039
ko05410	Hypertrophic cardiomyopathy (HCM)	1/694	100/7206	0.000885815441735
ko05152	Tuberculosis	6/694	187/7206	0.00100625421882
ko04726	Serotonergic synapse	3/694	137/7206	0.00107591439581
ko04915	Estrogen signaling pathway	3/694	131/7206	0.00151061031454
ko05166	HTLV-I infection	45/694	292/7206	0.0015469153025
ko04972	Pancreatic secretion	2/694	111/7206	0.00177602117702
ko04070	Phosphatidylinositol signaling system	2/694	112/7206	0.00179476740116
ko04120	Ubiquitin mediated proteolysis	25/694	138/7206	0.00185932049202
ko05031	Amphetamine addiction	1/694	91/7206	0.00190109724454
ko04152	AMPK signaling pathway	5/694	161/7206	0.00260075954129
ko04924	Renin secretion	1/694	86/7206	0.00277388962766
ko04920	Adipocytokine signaling pathway	1/694	89/7206	0.00297977691578
ko04750	Inflammatory mediator regulation of TRP channels	3/694	122/7206	0.0030415379195
ko04666	Fc gamma R-mediated phagocytosis	3/694	122/7206	0.0030415379195
ko04066	HIF-1 signaling pathway	3/694	123/7206	0.00304545155838
ko04668	TNF signaling pathway	3/694	120/7206	0.00436490707629
ko04072	Phospholipase D signaling pathway	8/694	197/7206	0.00460028811989
ko04380	Osteoclast differentiation	4/694	134/7206	0.00466204837751
ko00564	Glycerophospholipid metabolism	2/694	99/7206	0.00533027988436
ko05200	Pathways in cancer	30/694	492/7206	0.00541172198223
ko04721	Synaptic vesicle cycle	1/694	80/7206	0.00627579414427
ko05142	Chagas disease (American trypanosomiasis)	4/694	130/7206	0.00647874974571
ko04630	Jak-STAT signaling pathway	4/694	132/7206	0.00661029792729
ko04611	Platelet activation	6/694	163/7206	0.00666758239759
ko04064	NF-kappa B signaling pathway	2/694	96/7206	0.00780928948052
ko05030	Cocaine addiction	1/694	73/7206	0.00877462203143
ko00010	Glycolysis / Gluconeogenesis	1/694	74/7206	0.00883578261693
ko05134	Legionellosis	1/694	74/7206	0.00883578261693
ko04360	Axon guidance	11/694	233/7206	0.00888729498077
ko00230	Purine metabolism	30/694	194/7206	0.00897825776121
ko05145	Toxoplasmosis	4/694	126/7206	0.00898387141356
ko04922	Glucagon signaling pathway	4/694	128/7206	0.00920514169475
ko00562	Inositol phosphate metabolism	2/694	89/7206	0.0108270526653
ko04530	Tight junction	11/694	228/7206	0.0114744530873
ko04925	Aldosterone synthesis and secretion	3/694	105/7206	0.011930673971
ko04659	Th17 cell differentiation	3/694	106/7206	0.0119750845955
ko04931	Insulin resistance	5/694	137/7206	0.0123524438339
ko04115	p53 signaling pathway	14/694	74/7206	0.0148489796076
ko04620	Toll-like receptor signaling pathway	3/694	100/7206	0.016686651047
ko05231	Choline metabolism in cancer	5/694	134/7206	0.0169456991886
ko05202	Transcriptional misregulation in cancer	28/694	188/7206	0.0171043345451
ko04640	Hematopoietic cell lineage	1/694	64/7206	0.0187924706224
ko03060	Protein export	6/694	23/7206	0.0189100131987
ko05205	Proteoglycans in cancer	15/694	271/7206	0.0202677026501
ko00514	Other types of O-glycan biosynthesis	7/694	30/7206	0.0212085513242
ko04138	Autophagy - yeast	2/694	81/7206	0.0219608005296
ko01200	Carbon metabolism	5/694	128/7206	0.0226625462414
ko01212	Fatty acid metabolism	1/694	60/7206	0.0273949947704
ko00561	Glycerolipid metabolism	1/694	63/7206	0.0284843561371
ko00600	Sphingolipid metabolism	1/694	63/7206	0.0284843561371
ko04660	T cell receptor signaling pathway	5/694	124/7206	0.030573417419
ko04923	Regulation of lipolysis in adipocytes	2/694	77/7206	0.0311705699153
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	2/694	79/7206	0.0320567859252
ko04512	ECM-receptor interaction	2/694	79/7206	0.0320567859252
ko04142	Lysosome	7/694	151/7206	0.035394288972
ko04670	Leukocyte transendothelial migration	7/694	151/7206	0.035394288972
ko04933	AGE-RAGE signaling pathway in diabetic complications	6/694	135/7206	0.0382303973651
ko04962	Vasopressin-regulated water reabsorption	1/694	58/7206	0.040712307215
ko04912	GnRH signaling pathway	5/694	122/7206	0.0420470971242
ko04071	Sphingolipid signaling pathway	8/694	162/7206	0.0421706855258
ko04662	B cell receptor signaling pathway	3/694	88/7206	0.0444801417804
ko04146	Peroxisome	3/694	89/7206	0.0447685006963
ko05140	Leishmaniasis	2/694	75/7206	0.0455258751303
ko04910	Insulin signaling pathway	9/694	172/7206	0.0489257722187