ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	26/609	56/7206	4.42791560848e-14
ko04080	Neuroactive ligand-receptor interaction	83/609	423/7206	7.98884009183e-14
ko04724	Glutamatergic synapse	37/609	152/7206	2.04032343433e-09
ko04721	Synaptic vesicle cycle	25/609	80/7206	3.89240771569e-09
ko04260	Cardiac muscle contraction	28/609	98/7206	4.35856583841e-09
ko04728	Dopaminergic synapse	39/609	185/7206	5.56534808663e-08
ko04727	GABAergic synapse	28/609	110/7206	6.96585130825e-08
ko04950	Maturity onset diabetes of the young	13/609	29/7206	1.88539505183e-07
ko04723	Retrograde endocannabinoid signaling	35/609	175/7206	1.18010026789e-06
ko04713	Circadian entrainment	29/609	136/7206	2.26908864061e-06
ko04725	Cholinergic synapse	31/609	160/7206	9.06133923062e-06
ko04911	Insulin secretion	25/609	117/7206	1.09065041152e-05
ko04261	Adrenergic signaling in cardiomyocytes	36/609	205/7206	1.85703791038e-05
ko04512	ECM-receptor interaction	19/609	79/7206	2.17209043302e-05
ko04514	Cell adhesion molecules (CAMs)	26/609	130/7206	3.45239322839e-05
ko05032	Morphine addiction	23/609	110/7206	3.52645853952e-05
ko03040	Spliceosome	1/609	145/7206	5.98133237849e-05
ko04060	Cytokine-cytokine receptor interaction	3/609	191/7206	9.49605036066e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	17/609	74/7206	0.000108369714531
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/609	59/7206	0.000302880778338
ko05030	Cocaine addiction	16/609	73/7206	0.000306269783046
ko05410	Hypertrophic cardiomyopathy (HCM)	20/609	100/7206	0.000351351344443
ko05414	Dilated cardiomyopathy	21/609	112/7206	0.000428654545319
ko04964	Proximal tubule bicarbonate reclamation	9/609	29/7206	0.000443569118479
ko04974	Protein digestion and absorption	19/609	96/7206	0.00054859558552
ko05164	Influenza A	3/609	167/7206	0.000575900021721
ko05203	Viral carcinogenesis	9/609	277/7206	0.000586050824154
ko05168	Herpes simplex infection	4/609	182/7206	0.000652084936308
ko05162	Measles	1/609	120/7206	0.000668393549177
ko04360	Axon guidance	35/609	233/7206	0.000702686132439
ko05031	Amphetamine addiction	18/609	91/7206	0.00081105765055
ko04010	MAPK signaling pathway	44/609	321/7206	0.00132529108271
ko04978	Mineral absorption	10/609	40/7206	0.00142086883753
ko04024	cAMP signaling pathway	39/609	279/7206	0.00191223302444
ko04140	Autophagy - animal	4/609	164/7206	0.00253683278112
ko04151	PI3K-Akt signaling pathway	50/609	390/7206	0.00259382302509
ko03013	RNA transport	4/609	166/7206	0.00261196840765
ko00564	Glycerophospholipid metabolism	1/609	99/7206	0.00295887872468
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	15/609	79/7206	0.00311780564811
ko04120	Ubiquitin mediated proteolysis	3/609	138/7206	0.0046812691966
ko04141	Protein processing in endoplasmic reticulum	6/609	184/7206	0.00685584187582
ko05322	Systemic lupus erythematosus	4/609	151/7206	0.00696298966823
ko04976	Bile secretion	14/609	80/7206	0.00740600208111
ko04611	Platelet activation	5/609	163/7206	0.00955103685244
ko05166	HTLV-I infection	13/609	292/7206	0.00964701518316
ko04211	Longevity regulating pathway	3/609	123/7206	0.0127901058755
ko04621	NOD-like receptor signaling pathway	5/609	157/7206	0.0128615200357
ko03008	Ribosome biogenesis in eukaryotes	1/609	79/7206	0.0133992503808
ko04137	Mitophagy - animal	1/609	82/7206	0.0141618169082
ko04970	Salivary secretion	15/609	95/7206	0.0150605901723
ko04742	Taste transduction	11/609	61/7206	0.0166506762004
ko00350	Tyrosine metabolism	7/609	33/7206	0.018265229686
ko04726	Serotonergic synapse	20/609	137/7206	0.0183994965154
ko00310	Lysine degradation	1/609	73/7206	0.0194694236076
ko04150	mTOR signaling pathway	7/609	184/7206	0.0213015411345
ko04145	Phagosome	22/609	162/7206	0.022193870427
ko00430	Taurine and hypotaurine metabolism	4/609	14/7206	0.0254865997337
ko04217	Necroptosis	7/609	178/7206	0.0278277529966
ko05152	Tuberculosis	8/609	187/7206	0.0331098847025
ko04640	Hematopoietic cell lineage	1/609	64/7206	0.041062183841
ko04930	Type II diabetes mellitus	9/609	54/7206	0.0438478556977
ko04510	Focal adhesion	29/609	240/7206	0.0445891263957
ko03018	RNA degradation	2/609	84/7206	0.0457125704871
ko00950	Isoquinoline alkaloid biosynthesis	3/609	10/7206	0.0459836654209