ko pathway ratio_in_study ratio_in_pop p_value ko04974 Protein digestion and absorption 24/321 96/7206 2.25104405808e-12 ko04512 ECM-receptor interaction 18/321 79/7206 6.8689614246e-09 ko04260 Cardiac muscle contraction 19/321 98/7206 4.37367145337e-08 ko05410 Hypertrophic cardiomyopathy (HCM) 19/321 100/7206 6.15880391324e-08 ko05414 Dilated cardiomyopathy 18/321 112/7206 1.84510434742e-06 ko04950 Maturity onset diabetes of the young 9/321 29/7206 2.8074156543e-06 ko04510 Focal adhesion 26/321 240/7206 2.13565619048e-05 ko04261 Adrenergic signaling in cardiomyocytes 23/321 205/7206 3.70715337399e-05 ko04978 Mineral absorption 9/321 40/7206 4.96525120409e-05 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 12/321 79/7206 0.0001727755115 ko05203 Viral carcinogenesis 2/321 277/7206 0.000504847240057 ko04151 PI3K-Akt signaling pathway 32/321 390/7206 0.000863810755061 ko04964 Proximal tubule bicarbonate reclamation 6/321 29/7206 0.00148402138827 ko05034 Alcoholism 2/321 238/7206 0.00214244447727 ko04072 Phospholipase D signaling pathway 1/321 197/7206 0.00234854423527 ko05217 Basal cell carcinoma 9/321 68/7206 0.0029891668803 ko04217 Necroptosis 1/321 178/7206 0.00493531982312 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/321 182/7206 0.00516334138756 ko03013 RNA transport 1/321 166/7206 0.00709652965318 ko04976 Bile secretion 9/321 80/7206 0.00883150477106 ko04010 MAPK signaling pathway 24/321 321/7206 0.0119275709143 ko05224 Breast cancer 15/321 174/7206 0.0136257932795 ko04340 Hedgehog signaling pathway 7/321 58/7206 0.0139163365067 ko04977 Vitamin digestion and absorption 4/321 22/7206 0.0149629522648 ko04142 Lysosome 1/321 151/7206 0.0150387182267 ko04514 Cell adhesion molecules (CAMs) 12/321 130/7206 0.0153683788622 ko05200 Pathways in cancer 33/321 492/7206 0.0168769986633 ko04150 mTOR signaling pathway 2/321 184/7206 0.0176560428304 ko04141 Protein processing in endoplasmic reticulum 2/321 184/7206 0.0176560428304 ko05152 Tuberculosis 2/321 187/7206 0.0178768571197 ko04975 Fat digestion and absorption 5/321 35/7206 0.0183914404744 ko05167 Kaposi's sarcoma-associated herpesvirus infection 2/321 191/7206 0.0185785993961 ko05166 HTLV-I infection 5/321 292/7206 0.0191268758922 ko04550 Signaling pathways regulating pluripotency of stem cells 14/321 165/7206 0.0195286706658 ko04114 Oocyte meiosis 1/321 139/7206 0.0215132845089 ko04120 Ubiquitin mediated proteolysis 1/321 138/7206 0.0215304187437 ko00430 Taurine and hypotaurine metabolism 3/321 14/7206 0.02211103197 ko04144 Endocytosis 7/321 342/7206 0.0221395982163 ko04110 Cell cycle 1/321 145/7206 0.0223208073114 ko05161 Hepatitis B 2/321 173/7206 0.0248256263471 ko04341 Hedgehog signaling pathway - fly 5/321 38/7206 0.025529113414 ko05016 Huntington's disease 3/321 215/7206 0.0268745626095 ko00590 Arachidonic acid metabolism 6/321 52/7206 0.0270635223471 ko05202 Transcriptional misregulation in cancer 15/321 188/7206 0.0288054939723 ko04630 Jak-STAT signaling pathway 1/321 132/7206 0.0311491273903 ko05164 Influenza A 2/321 167/7206 0.0349719489004 ko05169 Epstein-Barr virus infection 3/321 206/7206 0.0370128515278 ko04911 Insulin secretion 10/321 117/7206 0.03992713384 ko04020 Calcium signaling pathway 19/321 265/7206 0.0461809636044 ko04621 NOD-like receptor signaling pathway 2/321 157/7206 0.0487375535132 ko04060 Cytokine-cytokine receptor interaction 3/321 191/7206 0.0490415566296 ko04360 Axon guidance 17/321 233/7206 0.0498357038151