ko pathway ratio_in_study ratio_in_pop p_value ko05217 Basal cell carcinoma 25/352 68/7206 2.7905824633e-16 ko04550 Signaling pathways regulating pluripotency of stem cells 32/352 165/7206 1.03396916197e-11 ko05224 Breast cancer 31/352 174/7206 2.13664018005e-10 ko05200 Pathways in cancer 56/352 492/7206 1.38978912511e-09 ko04340 Hedgehog signaling pathway 16/352 58/7206 9.15512688192e-09 ko05205 Proteoglycans in cancer 35/352 271/7206 9.47222743413e-08 ko04390 Hippo signaling pathway 27/352 188/7206 3.56319461554e-07 ko04950 Maturity onset diabetes of the young 10/352 29/7206 5.93322441782e-07 ko04310 Wnt signaling pathway 24/352 181/7206 6.79032048151e-06 ko04974 Protein digestion and absorption 16/352 96/7206 1.38088978583e-05 ko04360 Axon guidance 26/352 233/7206 6.92370543445e-05 ko04512 ECM-receptor interaction 13/352 79/7206 0.000101638122606 ko04916 Melanogenesis 17/352 142/7206 0.000520877002069 ko05203 Viral carcinogenesis 3/352 277/7206 0.000902944632114 ko04151 PI3K-Akt signaling pathway 34/352 390/7206 0.000953131783971 ko04510 Focal adhesion 23/352 240/7206 0.00190208890133 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/352 182/7206 0.00240192089042 ko05202 Transcriptional misregulation in cancer 19/352 188/7206 0.00278310833818 ko00514 Other types of O-glycan biosynthesis 6/352 30/7206 0.00285019655793 ko04330 Notch signaling pathway 9/352 62/7206 0.00292126874915 ko05410 Hypertrophic cardiomyopathy (HCM) 12/352 100/7206 0.00330808838633 ko04062 Chemokine signaling pathway 2/352 201/7206 0.00434019416634 ko05169 Epstein-Barr virus infection 2/352 206/7206 0.00449543350297 ko04975 Fat digestion and absorption 6/352 35/7206 0.0063445365051 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 5/352 26/7206 0.00760556013724 ko05218 Melanoma 10/352 85/7206 0.00811940507864 ko04341 Hedgehog signaling pathway - fly 6/352 38/7206 0.00954445166212 ko04144 Endocytosis 7/352 342/7206 0.00957374760783 ko03040 Spliceosome 1/352 145/7206 0.0102415219462 ko05222 Small cell lung cancer 10/352 89/7206 0.0111141574721 ko05168 Herpes simplex infection 2/352 182/7206 0.0129928562769 ko04114 Oocyte meiosis 1/352 139/7206 0.0150739393152 ko05010 Alzheimer's disease 3/352 202/7206 0.0189809072963 ko04977 Vitamin digestion and absorption 4/352 22/7206 0.0203587501495 ko05414 Dilated cardiomyopathy 11/352 112/7206 0.0239681397185 ko04722 Neurotrophin signaling pathway 2/352 160/7206 0.0247123458436 ko04072 Phospholipase D signaling pathway 3/352 197/7206 0.0270028343641 ko04260 Cardiac muscle contraction 10/352 98/7206 0.0279764380757 ko00330 Arginine and proline metabolism 7/352 61/7206 0.0282332745287 ko05162 Measles 1/352 120/7206 0.0308626112367 ko04660 T cell receptor signaling pathway 1/352 124/7206 0.0319007941132 ko04350 TGF-beta signaling pathway 10/352 103/7206 0.0339087811432 ko04724 Glutamatergic synapse 2/352 152/7206 0.0347129173284 ko05016 Huntington's disease 4/352 215/7206 0.0351816540501 ko04141 Protein processing in endoplasmic reticulum 3/352 184/7206 0.0358140519606 ko03410 Base excision repair 5/352 38/7206 0.0360711339028 ko04621 NOD-like receptor signaling pathway 2/352 157/7206 0.0361353451483 ko05166 HTLV-I infection 22/352 292/7206 0.0373791285354 ko00590 Arachidonic acid metabolism 6/352 52/7206 0.0399129243634