ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04110	Cell cycle	45/399	145/7206	1.20306985157e-22
ko04111	Cell cycle - yeast	32/399	90/7206	2.26992322923e-18
ko03460	Fanconi anemia pathway	24/399	51/7206	2.02499642799e-17
ko03440	Homologous recombination	21/399	41/7206	2.35111581974e-16
ko03040	Spliceosome	37/399	145/7206	1.15091894494e-15
ko03008	Ribosome biogenesis in eukaryotes	24/399	79/7206	2.36757878585e-12
ko04113	Meiosis - yeast	22/399	70/7206	9.32151660632e-12
ko03013	RNA transport	32/399	166/7206	3.29541892897e-10
ko03030	DNA replication	15/399	38/7206	5.20977871335e-10
ko03410	Base excision repair	14/399	38/7206	5.79582908978e-09
ko04144	Endocytosis	1/399	342/7206	8.05748674391e-08
ko00240	Pyrimidine metabolism	20/399	110/7206	1.97696761832e-06
ko05322	Systemic lupus erythematosus	24/399	151/7206	2.34942465284e-06
ko03430	Mismatch repair	8/399	22/7206	1.32510277346e-05
ko04151	PI3K-Akt signaling pathway	5/399	390/7206	1.86913191843e-05
ko04114	Oocyte meiosis	21/399	139/7206	2.25236084588e-05
ko04024	cAMP signaling pathway	2/399	279/7206	2.46870401258e-05
ko04261	Adrenergic signaling in cardiomyocytes	1/399	205/7206	0.000153055174984
ko04921	Oxytocin signaling pathway	1/399	209/7206	0.00015692846948
ko03420	Nucleotide excision repair	10/399	46/7206	0.000163460333789
ko05166	HTLV-I infection	32/399	292/7206	0.000194134831099
ko05010	Alzheimer's disease	1/399	202/7206	0.000231523171035
ko04010	MAPK signaling pathway	5/399	321/7206	0.000410374823462
ko04728	Dopaminergic synapse	1/399	185/7206	0.00048746721541
ko05152	Tuberculosis	1/399	187/7206	0.000495281179186
ko04914	Progesterone-mediated oocyte maturation	15/399	104/7206	0.000554597726643
ko03022	Basal transcription factors	9/399	44/7206	0.000560618607948
ko03018	RNA degradation	13/399	84/7206	0.000649313504385
ko04022	cGMP-PKG signaling pathway	2/399	216/7206	0.000713590916806
ko04371	Apelin signaling pathway	1/399	177/7206	0.000713835577698
ko04014	Ras signaling pathway	4/399	279/7206	0.000726714077406
ko05205	Proteoglycans in cancer	4/399	271/7206	0.00101770909888
ko04723	Retrograde endocannabinoid signaling	1/399	175/7206	0.00110502712522
ko04510	Focal adhesion	3/399	240/7206	0.00130475848995
ko04611	Platelet activation	1/399	163/7206	0.00153095769985
ko04530	Tight junction	3/399	228/7206	0.00177356711914
ko05203	Viral carcinogenesis	28/399	277/7206	0.00180707644683
ko04060	Cytokine-cytokine receptor interaction	2/399	191/7206	0.00209351430929
ko04072	Phospholipase D signaling pathway	2/399	197/7206	0.0021921417595
ko05012	Parkinson's disease	1/399	155/7206	0.00223615033217
ko04725	Cholinergic synapse	1/399	160/7206	0.00233058470182
ko04015	Rap1 signaling pathway	5/399	278/7206	0.00292929773265
ko04724	Glutamatergic synapse	1/399	152/7206	0.00335528503337
ko05034	Alcoholism	24/399	238/7206	0.00369259108641
ko04120	Ubiquitin mediated proteolysis	16/399	138/7206	0.00420166054933
ko03015	mRNA surveillance pathway	12/399	93/7206	0.00497998810404
ko05202	Transcriptional misregulation in cancer	20/399	188/7206	0.00509088471212
ko04810	Regulation of actin cytoskeleton	5/399	264/7206	0.00554067491175
ko04218	Cellular senescence	19/399	177/7206	0.00658974818811
ko04933	AGE-RAGE signaling pathway in diabetic complications	1/399	135/7206	0.00693441742943
ko04713	Circadian entrainment	1/399	136/7206	0.0069802861761
ko04062	Chemokine signaling pathway	3/399	201/7206	0.00701002241994
ko04726	Serotonergic synapse	1/399	137/7206	0.00705069880493
ko04115	p53 signaling pathway	10/399	74/7206	0.00723115585651
ko03450	Non-homologous end-joining	4/399	15/7206	0.00775795073265
ko04071	Sphingolipid signaling pathway	2/399	162/7206	0.00864149243024
ko05145	Toxoplasmosis	1/399	126/7206	0.0100364613477
ko00190	Oxidative phosphorylation	1/399	127/7206	0.0100415602153
ko05142	Chagas disease (American trypanosomiasis)	1/399	130/7206	0.0102621408146
ko04514	Cell adhesion molecules (CAMs)	1/399	130/7206	0.0102621408146
ko04915	Estrogen signaling pathway	1/399	131/7206	0.0104048793767
ko04722	Neurotrophin signaling pathway	2/399	160/7206	0.0127140079689
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/399	182/7206	0.0133830985228
ko04660	T cell receptor signaling pathway	1/399	124/7206	0.0151251535552
ko04142	Lysosome	2/399	151/7206	0.0176133881595
ko04670	Leukocyte transendothelial migration	2/399	151/7206	0.0176133881595
ko05160	Hepatitis C	2/399	153/7206	0.0180407779476
ko04070	Phosphatidylinositol signaling system	1/399	112/7206	0.0210388678792
ko04911	Insulin secretion	1/399	117/7206	0.021947511306
ko04659	Th17 cell differentiation	1/399	106/7206	0.030480070974
ko01521	EGFR tyrosine kinase inhibitor resistance	1/399	106/7206	0.030480070974
ko04727	GABAergic synapse	1/399	110/7206	0.0317846251545
ko05032	Morphine addiction	1/399	110/7206	0.0317846251545
ko04972	Pancreatic secretion	1/399	111/7206	0.0323396668401
ko04630	Jak-STAT signaling pathway	2/399	132/7206	0.0341896377664
ko04380	Osteoclast differentiation	2/399	134/7206	0.0343109640677
ko05231	Choline metabolism in cancer	2/399	134/7206	0.0343109640677
ko04931	Insulin resistance	2/399	137/7206	0.0350861267069
ko05167	Kaposi's sarcoma-associated herpesvirus infection	4/399	191/7206	0.0351604434469
ko04152	AMPK signaling pathway	3/399	161/7206	0.0352804674757
ko04145	Phagosome	3/399	162/7206	0.0354094662791
ko04360	Axon guidance	6/399	233/7206	0.0410922201552
ko04650	Natural killer cell mediated cytotoxicity	1/399	97/7206	0.0437411230346
ko05132	Salmonella infection	1/399	98/7206	0.0437942336282
ko04971	Gastric acid secretion	1/399	98/7206	0.0437942336282
ko00564	Glycerophospholipid metabolism	1/399	99/7206	0.0439726921379
ko04620	Toll-like receptor signaling pathway	1/399	100/7206	0.0442759452488
ko04540	Gap junction	2/399	128/7206	0.0483873226132