ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 27/267 191/7206 1.41594005088e-09 ko00643 Styrene degradation 4/267 4/7206 1.84428203964e-06 ko04621 NOD-like receptor signaling pathway 19/267 157/7206 4.73329267261e-06 ko05164 Influenza A 19/267 167/7206 1.17530885156e-05 ko00140 Steroid hormone biosynthesis 9/267 41/7206 1.42138886392e-05 ko00350 Tyrosine metabolism 8/267 33/7206 1.98222382521e-05 ko04380 Osteoclast differentiation 16/267 134/7206 3.20722926121e-05 ko04512 ECM-receptor interaction 11/267 79/7206 0.000141567080182 ko04064 NF-kappa B signaling pathway 12/267 96/7206 0.000203291741816 ko05145 Toxoplasmosis 14/267 126/7206 0.000217918605972 ko00360 Phenylalanine metabolism 5/267 17/7206 0.000288492970797 ko04657 IL-17 signaling pathway 11/267 87/7206 0.000337499523642 ko04622 RIG-I-like receptor signaling pathway 9/267 62/7206 0.000416451964244 ko04668 TNF signaling pathway 13/267 120/7206 0.000467674718748 ko00120 Primary bile acid biosynthesis 5/267 20/7206 0.000659696824132 ko05133 Pertussis 10/267 87/7206 0.00132878495537 ko05204 Chemical carcinogenesis 7/267 48/7206 0.00177384830949 ko04080 Neuroactive ligand-receptor interaction 5/267 423/7206 0.00209809361151 ko05034 Alcoholism 1/267 238/7206 0.00239854575554 ko05131 Shigellosis 9/267 82/7206 0.00315828961459 ko00980 Metabolism of xenobiotics by cytochrome P450 6/267 40/7206 0.00325057973053 ko04217 Necroptosis 15/267 178/7206 0.00352666000986 ko04623 Cytosolic DNA-sensing pathway 6/267 41/7206 0.00369201696925 ko01524 Platinum drug resistance 8/267 76/7206 0.00680860111778 ko04215 Apoptosis - multiple species 6/267 47/7206 0.00732889723302 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/267 4/7206 0.00781057113384 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 8/267 79/7206 0.00856742666004 ko05152 Tuberculosis 14/267 187/7206 0.0101978423359 ko04672 Intestinal immune network for IgA production 5/267 37/7206 0.0111037759856 ko00982 Drug metabolism - cytochrome P450 5/267 37/7206 0.0111037759856 ko04620 Toll-like receptor signaling pathway 9/267 100/7206 0.0115285660848 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/267 5/7206 0.012700328256 ko04310 Wnt signaling pathway 1/267 181/7206 0.015173166058 ko00480 Glutathione metabolism 6/267 55/7206 0.0154858263175 ko05321 Inflammatory bowel disease (IBD) 6/267 56/7206 0.016822699689 ko05323 Rheumatoid arthritis 8/267 89/7206 0.016921865892 ko00362 Benzoate degradation 2/267 6/7206 0.0185875931149 ko05134 Legionellosis 7/267 74/7206 0.0192362843922 ko03013 RNA transport 1/267 166/7206 0.0217719707296 ko00720 Carbon fixation pathways in prokaryotes 3/267 17/7206 0.0232707412657 ko05340 Primary immunodeficiency 4/267 30/7206 0.023659572538 ko04658 Th1 and Th2 cell differentiation 8/267 96/7206 0.0255066693368 ko05132 Salmonella infection 8/267 98/7206 0.0284340778497 ko00564 Glycerophospholipid metabolism 8/267 99/7206 0.0299816321359 ko04630 Jak-STAT signaling pathway 10/267 132/7206 0.0308720992018 ko00260 Glycine, serine and threonine metabolism 5/267 48/7206 0.0314421007739 ko05410 Hypertrophic cardiomyopathy (HCM) 8/267 100/7206 0.0315862465751 ko00740 Riboflavin metabolism 2/267 8/7206 0.0330388701926 ko04933 AGE-RAGE signaling pathway in diabetic complications 10/267 135/7206 0.0337325555495 ko04014 Ras signaling pathway 4/267 279/7206 0.0351718579015 ko04015 Rap1 signaling pathway 4/267 278/7206 0.0351889398116 ko00401 Novobiocin biosynthesis 1/267 1/7206 0.0370524562864 ko05161 Hepatitis B 12/267 173/7206 0.0372662309816 ko00627 Aminobenzoate degradation 2/267 9/7206 0.0414560876599 ko05150 Staphylococcus aureus infection 4/267 36/7206 0.0428442524433 ko04210 Apoptosis 12/267 180/7206 0.0432009556317 ko04662 B cell receptor signaling pathway 7/267 88/7206 0.0440654961085 ko05222 Small cell lung cancer 7/267 89/7206 0.0463826352731 ko04390 Hippo signaling pathway 2/267 188/7206 0.0490368934259 ko04660 T cell receptor signaling pathway 9/267 124/7206 0.0491007749778 ko04360 Axon guidance 3/267 233/7206 0.0498444358924