ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 30/210 191/7206 1.7652647265e-14 ko05340 Primary immunodeficiency 13/210 30/7206 5.84860917156e-13 ko04650 Natural killer cell mediated cytotoxicity 20/210 97/7206 2.99365220369e-12 ko05140 Leishmaniasis 15/210 75/7206 2.74390264993e-09 ko05150 Staphylococcus aureus infection 11/210 36/7206 3.14427020363e-09 ko05320 Autoimmune thyroid disease 10/210 29/7206 4.40715612871e-09 ko05321 Inflammatory bowel disease (IBD) 13/210 56/7206 4.72506059075e-09 ko05330 Allograft rejection 9/210 24/7206 1.14338152514e-08 ko05152 Tuberculosis 22/210 187/7206 1.91268746275e-08 ko05145 Toxoplasmosis 18/210 126/7206 1.93281779885e-08 ko04380 Osteoclast differentiation 18/210 134/7206 5.15833674724e-08 ko04659 Th17 cell differentiation 16/210 106/7206 5.55901320104e-08 ko04672 Intestinal immune network for IgA production 10/210 37/7206 6.2482136087e-08 ko04612 Antigen processing and presentation 13/210 77/7206 2.67588570885e-07 ko05332 Graft-versus-host disease 7/210 18/7206 3.91411282148e-07 ko04660 T cell receptor signaling pathway 16/210 124/7206 5.15007392053e-07 ko05168 Herpes simplex infection 19/210 182/7206 1.22108517628e-06 ko05164 Influenza A 18/210 167/7206 1.48050950379e-06 ko04064 NF-kappa B signaling pathway 13/210 96/7206 3.60608135305e-06 ko04145 Phagosome 17/210 162/7206 4.24061824784e-06 ko04630 Jak-STAT signaling pathway 15/210 132/7206 5.96417633308e-06 ko05323 Rheumatoid arthritis 12/210 89/7206 9.02596373994e-06 ko04658 Th1 and Th2 cell differentiation 12/210 96/7206 1.98518092684e-05 ko04062 Chemokine signaling pathway 18/210 201/7206 2.04167267839e-05 ko04940 Type I diabetes mellitus 7/210 32/7206 2.92328636754e-05 ko05144 Malaria 8/210 45/7206 3.8769208083e-05 ko05162 Measles 13/210 120/7206 4.22427780465e-05 ko04640 Hematopoietic cell lineage 9/210 64/7206 8.74828309153e-05 ko04610 Complement and coagulation cascades 10/210 79/7206 8.87318985316e-05 ko05310 Asthma 5/210 17/7206 9.31605198254e-05 ko04621 NOD-like receptor signaling pathway 14/210 157/7206 0.000182049865509 ko05133 Pertussis 10/210 87/7206 0.000201167054929 ko04666 Fc gamma R-mediated phagocytosis 12/210 122/7206 0.000212089081007 ko04662 B cell receptor signaling pathway 10/210 88/7206 0.000221279587898 ko04611 Platelet activation 14/210 163/7206 0.00026984751682 ko04514 Cell adhesion molecules (CAMs) 12/210 130/7206 0.00038387035982 ko04217 Necroptosis 14/210 178/7206 0.000661854275184 ko05416 Viral myocarditis 7/210 55/7206 0.000998726375064 ko05142 Chagas disease (American trypanosomiasis) 11/210 130/7206 0.00138156817643 ko04664 Fc epsilon RI signaling pathway 8/210 77/7206 0.0017037277413 ko05132 Salmonella infection 9/210 98/7206 0.00212761068731 ko04620 Toll-like receptor signaling pathway 9/210 100/7206 0.0024463541159 ko04670 Leukocyte transendothelial migration 11/210 151/7206 0.0044856568474 ko05161 Hepatitis B 12/210 173/7206 0.00452727876681 ko03050 Proteasome 6/210 54/7206 0.0045888202758 ko05167 Kaposi's sarcoma-associated herpesvirus infection 12/210 191/7206 0.0130315741108 ko04144 Endocytosis 17/210 342/7206 0.0302013628664 ko05010 Alzheimer's disease 1/210 202/7206 0.0316764175508 ko05131 Shigellosis 6/210 82/7206 0.0319172844398