ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 30/390 191/7206 9.84782999911e-08 ko00120 Primary bile acid biosynthesis 9/390 20/7206 3.58577577444e-07 ko00350 Tyrosine metabolism 10/390 33/7206 5.78974365294e-06 ko04380 Osteoclast differentiation 20/390 134/7206 3.04561999243e-05 ko00140 Steroid hormone biosynthesis 10/390 41/7206 4.74804034913e-05 ko00051 Fructose and mannose metabolism 10/390 42/7206 5.93584182207e-05 ko05164 Influenza A 22/390 167/7206 8.7245503018e-05 ko00380 Tryptophan metabolism 10/390 50/7206 0.000280984692867 ko00592 alpha-Linolenic acid metabolism 6/390 19/7206 0.000359025809995 ko00590 Arachidonic acid metabolism 10/390 52/7206 0.000392768722914 ko04658 Th1 and Th2 cell differentiation 14/390 96/7206 0.000600050496958 ko00643 Styrene degradation 3/390 4/7206 0.000604145318208 ko04672 Intestinal immune network for IgA production 8/390 37/7206 0.000660845254156 ko05162 Measles 16/390 120/7206 0.000693836921415 ko05321 Inflammatory bowel disease (IBD) 10/390 56/7206 0.000728471342125 ko03013 RNA transport 1/390 166/7206 0.00153664154857 ko04659 Th17 cell differentiation 14/390 106/7206 0.00161994371619 ko00360 Phenylalanine metabolism 5/390 17/7206 0.00162922838786 ko04710 Circadian rhythm 8/390 43/7206 0.00186751555289 ko04064 NF-kappa B signaling pathway 13/390 96/7206 0.00187257917749 ko04650 Natural killer cell mediated cytotoxicity 13/390 97/7206 0.00205907566612 ko04662 B cell receptor signaling pathway 12/390 88/7206 0.00260945676989 ko04390 Hippo signaling pathway 2/390 188/7206 0.00300425813863 ko00982 Drug metabolism - cytochrome P450 7/390 37/7206 0.00323261531747 ko04022 cGMP-PKG signaling pathway 22/390 216/7206 0.00349871433873 ko05145 Toxoplasmosis 15/390 126/7206 0.00402059505291 ko05340 Primary immunodeficiency 6/390 30/7206 0.00473912566256 ko03040 Spliceosome 1/390 145/7206 0.00477588397664 ko05160 Hepatitis C 17/390 153/7206 0.00543645991768 ko04668 TNF signaling pathway 14/390 120/7206 0.00635058401307 ko00565 Ether lipid metabolism 7/390 42/7206 0.00671460731347 ko05140 Leishmaniasis 10/390 75/7206 0.00679982872956 ko04657 IL-17 signaling pathway 11/390 87/7206 0.00693797825761 ko04611 Platelet activation 17/390 163/7206 0.0079561630487 ko05167 Kaposi's sarcoma-associated herpesvirus infection 19/390 191/7206 0.00885869576305 ko04070 Phosphatidylinositol signaling system 13/390 112/7206 0.00908785998199 ko05161 Hepatitis B 18/390 173/7206 0.00927011613614 ko03010 Ribosome 1/390 129/7206 0.0100682973325 ko04062 Chemokine signaling pathway 20/390 201/7206 0.0101412111415 ko03320 PPAR signaling pathway 9/390 69/7206 0.0115200541594 ko05168 Herpes simplex infection 18/390 182/7206 0.0118072888273 ko04621 NOD-like receptor signaling pathway 16/390 157/7206 0.0121126265596 ko05204 Chemical carcinogenesis 7/390 48/7206 0.0138874134999 ko00950 Isoquinoline alkaloid biosynthesis 3/390 10/7206 0.0141949622132 ko04630 Jak-STAT signaling pathway 14/390 132/7206 0.0169911111982 ko04622 RIG-I-like receptor signaling pathway 8/390 62/7206 0.0178412071806 ko05231 Choline metabolism in cancer 14/390 134/7206 0.0180455301176 ko00980 Metabolism of xenobiotics by cytochrome P450 6/390 40/7206 0.0194555596547 ko00564 Glycerophospholipid metabolism 11/390 99/7206 0.0214495777365 ko04960 Aldosterone-regulated sodium reabsorption 6/390 41/7206 0.0217860332568 ko04666 Fc gamma R-mediated phagocytosis 13/390 122/7206 0.0229659485858 ko04660 T cell receptor signaling pathway 13/390 124/7206 0.0240772966349 ko00100 Steroid biosynthesis 4/390 21/7206 0.0242965134092 ko00983 Drug metabolism - other enzymes 6/390 42/7206 0.0242979375805 ko00830 Retinol metabolism 6/390 42/7206 0.0242979375805 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/390 5/7206 0.0261978477966 ko00480 Glutathione metabolism 7/390 55/7206 0.0277560018519 ko00052 Galactose metabolism 5/390 33/7206 0.0307335616469 ko05031 Amphetamine addiction 10/390 91/7206 0.0307343456797 ko05152 Tuberculosis 17/390 187/7206 0.0320095903043 ko00362 Benzoate degradation 2/390 6/7206 0.0379052053677 ko04217 Necroptosis 16/390 178/7206 0.0422699679479 ko01040 Biosynthesis of unsaturated fatty acids 4/390 25/7206 0.0433716078846