ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	163/841	423/7206	8.39525714011e-50
ko05033	Nicotine addiction	44/841	56/7206	4.55787384265e-31
ko04724	Glutamatergic synapse	73/841	152/7206	2.01561450548e-29
ko04728	Dopaminergic synapse	71/841	185/7206	1.84326037158e-21
ko04721	Synaptic vesicle cycle	44/841	80/7206	3.70322824206e-21
ko05032	Morphine addiction	52/841	110/7206	7.95823772411e-21
ko04727	GABAergic synapse	51/841	110/7206	5.63342437618e-20
ko04713	Circadian entrainment	57/841	136/7206	1.42463329493e-19
ko04723	Retrograde endocannabinoid signaling	63/841	175/7206	1.65606375221e-17
ko04725	Cholinergic synapse	59/841	160/7206	4.95887285748e-17
ko04024	cAMP signaling pathway	81/841	279/7206	1.2875085617e-15
ko04911	Insulin secretion	45/841	117/7206	4.82580284103e-14
ko04742	Taste transduction	31/841	61/7206	5.28244024271e-14
ko05031	Amphetamine addiction	36/841	91/7206	6.52578689008e-12
ko04726	Serotonergic synapse	46/841	137/7206	7.43678786387e-12
ko04921	Oxytocin signaling pathway	60/841	209/7206	1.32257047034e-11
ko04261	Adrenergic signaling in cardiomyocytes	57/841	205/7206	1.36196561372e-10
ko04020	Calcium signaling pathway	67/841	265/7206	3.1173970222e-10
ko04720	Long-term potentiation	34/841	99/7206	2.16571306576e-09
ko05030	Cocaine addiction	27/841	73/7206	1.62858841495e-08
ko04010	MAPK signaling pathway	69/841	321/7206	2.70802271321e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	25/841	74/7206	4.23271811296e-07
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/841	79/7206	4.46819513155e-07
ko05203	Viral carcinogenesis	9/841	277/7206	4.94545082398e-07
ko03040	Spliceosome	1/841	145/7206	5.61970735829e-07
ko04970	Salivary secretion	29/841	95/7206	5.93788478267e-07
ko04966	Collecting duct acid secretion	13/841	26/7206	1.64996482214e-06
ko05168	Herpes simplex infection	4/841	182/7206	3.40259708796e-06
ko04060	Cytokine-cytokine receptor interaction	5/841	191/7206	9.54472497285e-06
ko04514	Cell adhesion molecules (CAMs)	33/841	130/7206	1.11554984639e-05
ko04971	Gastric acid secretion	27/841	98/7206	1.72361080774e-05
ko04925	Aldosterone synthesis and secretion	28/841	105/7206	1.88540910369e-05
ko05164	Influenza A	4/841	167/7206	2.29120619284e-05
ko04260	Cardiac muscle contraction	26/841	98/7206	4.17292329032e-05
ko04360	Axon guidance	48/841	233/7206	6.66414188912e-05
ko04120	Ubiquitin mediated proteolysis	3/841	138/7206	7.43012923589e-05
ko05322	Systemic lupus erythematosus	4/841	151/7206	9.31178400163e-05
ko03013	RNA transport	5/841	166/7206	0.000114137670862
ko05110	Vibrio cholerae infection	18/841	63/7206	0.000209394348628
ko04022	cGMP-PKG signaling pathway	44/841	216/7206	0.000211537025497
ko04621	NOD-like receptor signaling pathway	5/841	157/7206	0.000219600767326
ko04730	Long-term depression	21/841	78/7206	0.000221452465267
ko04924	Renin secretion	22/841	86/7206	0.000277333618165
ko04972	Pancreatic secretion	26/841	111/7206	0.00045556721548
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/841	14/7206	0.000470438701069
ko05414	Dilated cardiomyopathy	26/841	112/7206	0.000498075561191
ko04744	Phototransduction	12/841	36/7206	0.000512562872858
ko04740	Olfactory transduction	20/841	80/7206	0.000709195100082
ko04745	Phototransduction - fly	12/841	38/7206	0.000889139749439
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/841	182/7206	0.000941978129732
ko03008	Ribosome biogenesis in eukaryotes	1/841	79/7206	0.00116065677501
ko04612	Antigen processing and presentation	1/841	77/7206	0.00182112975502
ko05205	Proteoglycans in cancer	16/841	271/7206	0.00188301042433
ko04540	Gap junction	27/841	128/7206	0.00196085446166
ko05162	Measles	4/841	120/7206	0.0022355456358
ko04750	Inflammatory mediator regulation of TRP channels	26/841	122/7206	0.00239763747782
ko04214	Apoptosis - fly	1/841	72/7206	0.00254759672578
ko00310	Lysine degradation	1/841	73/7206	0.00263102373769
ko05410	Hypertrophic cardiomyopathy (HCM)	22/841	100/7206	0.00263357009963
ko05169	Epstein-Barr virus infection	11/841	206/7206	0.00273737982711
ko04014	Ras signaling pathway	49/841	279/7206	0.00303879049508
ko04072	Phospholipase D signaling pathway	37/841	197/7206	0.00317904099747
ko04140	Autophagy - animal	8/841	164/7206	0.0042970823236
ko04964	Proximal tubule bicarbonate reclamation	9/841	29/7206	0.00441726437869
ko05120	Epithelial cell signaling in Helicobacter pylori infection	20/841	92/7206	0.00493849582147
ko04141	Protein processing in endoplasmic reticulum	10/841	184/7206	0.00506661864958
ko05161	Hepatitis B	9/841	173/7206	0.00545026974594
ko04915	Estrogen signaling pathway	26/841	131/7206	0.00566010465755
ko04070	Phosphatidylinositol signaling system	23/841	112/7206	0.00676860101584
ko05166	HTLV-I infection	20/841	292/7206	0.00683882854468
ko04110	Cell cycle	7/841	145/7206	0.00827183866949
ko04930	Type II diabetes mellitus	13/841	54/7206	0.00904512716956
ko05140	Leishmaniasis	2/841	75/7206	0.0101775879125
ko04626	Plant-pathogen interaction	6/841	18/7206	0.0133718057503
ko00240	Pyrimidine metabolism	5/841	110/7206	0.0157911931784
ko04064	NF-kappa B signaling pathway	4/841	96/7206	0.0159371202498
ko05016	Huntington's disease	14/841	215/7206	0.0170178603182
ko00480	Glutathione metabolism	1/841	55/7206	0.0180097754493
ko05323	Rheumatoid arthritis	18/841	89/7206	0.0185058193674
ko05321	Inflammatory bowel disease (IBD)	1/841	56/7206	0.0186413159621
ko04630	Jak-STAT signaling pathway	7/841	132/7206	0.0192127467343
ko04015	Rap1 signaling pathway	45/841	278/7206	0.0217760246312
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/841	59/7206	0.0222717833305
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/841	15/7206	0.0236115414138
ko04973	Carbohydrate digestion and absorption	10/841	42/7206	0.025455243652
ko04350	TGF-beta signaling pathway	5/841	103/7206	0.0291297169231
ko04640	Hematopoietic cell lineage	2/841	64/7206	0.0295927021236
ko04146	Peroxisome	4/841	89/7206	0.0300975269501
ko04976	Bile secretion	16/841	80/7206	0.0329806845229
ko05215	Prostate cancer	6/841	111/7206	0.0363184886183
ko00620	Pyruvate metabolism	1/841	46/7206	0.0378249203349
ko03420	Nucleotide excision repair	1/841	46/7206	0.0378249203349
ko05220	Chronic myeloid leukemia	4/841	85/7206	0.0410703471872
ko00330	Arginine and proline metabolism	2/841	61/7206	0.0424171755136
ko04217	Necroptosis	12/841	178/7206	0.043324559054
ko04330	Notch signaling pathway	2/841	62/7206	0.0434369189994
ko04722	Neurotrophin signaling pathway	27/841	160/7206	0.0455577879491
ko04550	Signaling pathways regulating pluripotency of stem cells	11/841	165/7206	0.0484553248361