ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	189/1265	423/7206	4.11102333911e-41
ko04724	Glutamatergic synapse	84/1265	152/7206	2.58508031119e-26
ko05033	Nicotine addiction	46/1265	56/7206	5.06777186807e-26
ko05032	Morphine addiction	65/1265	110/7206	8.8811834265e-23
ko04713	Circadian entrainment	72/1265	136/7206	3.18345054666e-21
ko04727	GABAergic synapse	63/1265	110/7206	4.16685128844e-21
ko04725	Cholinergic synapse	73/1265	160/7206	8.74810430304e-17
ko04728	Dopaminergic synapse	80/1265	185/7206	1.35431907443e-16
ko04020	Calcium signaling pathway	102/1265	265/7206	1.58690859937e-16
ko04723	Retrograde endocannabinoid signaling	74/1265	175/7206	9.6874673982e-15
ko04024	cAMP signaling pathway	101/1265	279/7206	3.11140172762e-14
ko04744	Phototransduction	27/1265	36/7206	5.77909550662e-14
ko04911	Insulin secretion	54/1265	117/7206	5.4842785785e-13
ko04721	Synaptic vesicle cycle	42/1265	80/7206	9.88547810383e-13
ko04742	Taste transduction	35/1265	61/7206	2.57205310077e-12
ko04921	Oxytocin signaling pathway	78/1265	209/7206	7.05389502043e-12
ko04726	Serotonergic synapse	56/1265	137/7206	8.55725018233e-11
ko03010	Ribosome	1/1265	129/7206	5.61945424987e-10
ko05031	Amphetamine addiction	40/1265	91/7206	3.47143147751e-09
ko04971	Gastric acid secretion	42/1265	98/7206	3.59235113147e-09
ko04925	Aldosterone synthesis and secretion	44/1265	105/7206	4.90577742113e-09
ko03040	Spliceosome	3/1265	145/7206	6.22175582447e-09
ko04720	Long-term potentiation	41/1265	99/7206	2.27261523891e-08
ko04970	Salivary secretion	40/1265	95/7206	2.51354500015e-08
ko03013	RNA transport	6/1265	166/7206	4.31271099896e-08
ko05322	Systemic lupus erythematosus	5/1265	151/7206	1.04969250173e-07
ko05203	Viral carcinogenesis	20/1265	277/7206	6.72582352527e-07
ko04022	cGMP-PKG signaling pathway	67/1265	216/7206	1.03829608616e-06
ko04110	Cell cycle	6/1265	145/7206	1.34290490136e-06
ko04261	Adrenergic signaling in cardiomyocytes	64/1265	205/7206	1.41734549765e-06
ko04976	Bile secretion	32/1265	80/7206	1.86815069155e-06
ko05030	Cocaine addiction	29/1265	73/7206	6.75893702445e-06
ko04972	Pancreatic secretion	39/1265	111/7206	6.94046775479e-06
ko04740	Olfactory transduction	31/1265	80/7206	8.65294081524e-06
ko04070	Phosphatidylinositol signaling system	38/1265	112/7206	2.49447010241e-05
ko04072	Phospholipase D signaling pathway	57/1265	197/7206	5.89115852545e-05
ko05168	Herpes simplex infection	13/1265	182/7206	6.56287065608e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1265	79/7206	7.09477856376e-05
ko04745	Phototransduction - fly	17/1265	38/7206	8.9530132921e-05
ko04730	Long-term depression	28/1265	78/7206	0.000118836906711
ko04120	Ubiquitin mediated proteolysis	9/1265	138/7206	0.000250388665694
ko04924	Renin secretion	29/1265	86/7206	0.000274135235941
ko05014	Amyotrophic lateral sclerosis (ALS)	26/1265	74/7206	0.000288291804081
ko05169	Epstein-Barr virus infection	18/1265	206/7206	0.000380900270583
ko05164	Influenza A	13/1265	167/7206	0.000411717067395
ko04621	NOD-like receptor signaling pathway	12/1265	157/7206	0.000428018466323
ko04750	Inflammatory mediator regulation of TRP channels	37/1265	122/7206	0.00044450623587
ko04014	Ras signaling pathway	71/1265	279/7206	0.00071256669198
ko04710	Circadian rhythm	17/1265	43/7206	0.000784591943224
ko04141	Protein processing in endoplasmic reticulum	16/1265	184/7206	0.000784713245614
ko04360	Axon guidance	61/1265	233/7206	0.00082240657746
ko04514	Cell adhesion molecules (CAMs)	38/1265	130/7206	0.000987831800875
ko05161	Hepatitis B	15/1265	173/7206	0.00112669184094
ko04010	MAPK signaling pathway	79/1265	321/7206	0.0011907549933
ko04270	Vascular smooth muscle contraction	43/1265	154/7206	0.00121670897551
ko04060	Cytokine-cytokine receptor interaction	18/1265	191/7206	0.00192604008976
ko04964	Proximal tubule bicarbonate reclamation	12/1265	29/7206	0.0022295617055
ko04915	Estrogen signaling pathway	37/1265	131/7206	0.00235126230609
ko04966	Collecting duct acid secretion	11/1265	26/7206	0.00274479068373
ko05144	Malaria	1/1265	45/7206	0.00274690864298
ko03420	Nucleotide excision repair	1/1265	46/7206	0.00279876184689
ko04922	Glucagon signaling pathway	36/1265	128/7206	0.00308562629759
ko04540	Gap junction	36/1265	128/7206	0.00308562629759
ko05140	Leishmaniasis	4/1265	75/7206	0.00325963448697
ko04630	Jak-STAT signaling pathway	11/1265	132/7206	0.00363440993296
ko03022	Basal transcription factors	1/1265	44/7206	0.00430220043996
ko05162	Measles	10/1265	120/7206	0.00520068554017
ko02010	ABC transporters	14/1265	39/7206	0.00524226064031
ko04932	Non-alcoholic fatty liver disease (NAFLD)	18/1265	182/7206	0.0054415878933
ko05205	Proteoglycans in cancer	31/1265	271/7206	0.0055991616613
ko04622	RIG-I-like receptor signaling pathway	3/1265	62/7206	0.00634146319541
ko04064	NF-kappa B signaling pathway	7/1265	96/7206	0.00634758691353
ko04113	Meiosis - yeast	4/1265	70/7206	0.00654476853426
ko04626	Plant-pathogen interaction	8/1265	18/7206	0.00731392701265
ko03018	RNA degradation	6/1265	84/7206	0.00891046450141
ko04371	Apelin signaling pathway	45/1265	177/7206	0.00891434308996
ko00630	Glyoxylate and dicarboxylate metabolism	1/1265	38/7206	0.00943052672225
ko03410	Base excision repair	1/1265	38/7206	0.00943052672225
ko05166	HTLV-I infection	35/1265	292/7206	0.0094493337584
ko05130	Pathogenic Escherichia coli infection	5/1265	77/7206	0.00949624794343
ko04612	Antigen processing and presentation	5/1265	77/7206	0.00949624794343
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/1265	79/7206	0.0106865452839
ko05016	Huntington's disease	24/1265	215/7206	0.0106937244795
ko05231	Choline metabolism in cancer	35/1265	134/7206	0.0114227930037
ko05219	Bladder cancer	2/1265	48/7206	0.0117848686975
ko05131	Shigellosis	6/1265	82/7206	0.0122935510874
ko05150	Staphylococcus aureus infection	1/1265	36/7206	0.0142251019525
ko04923	Regulation of lipolysis in adipocytes	22/1265	77/7206	0.0152719233314
ko04657	IL-17 signaling pathway	7/1265	87/7206	0.0156375721139
ko05133	Pertussis	7/1265	87/7206	0.0156375721139
ko04711	Circadian rhythm - fly	6/1265	13/7206	0.0161819882529
ko05145	Toxoplasmosis	12/1265	126/7206	0.0174072022651
ko00280	Valine, leucine and isoleucine degradation	3/1265	54/7206	0.0181055188985
ko03015	mRNA surveillance pathway	8/1265	93/7206	0.0193816126179
ko00860	Porphyrin and chlorophyll metabolism	1/1265	34/7206	0.0215346772008
ko04960	Aldosterone-regulated sodium reabsorption	13/1265	41/7206	0.0230700136435
ko05414	Dilated cardiomyopathy	29/1265	112/7206	0.0239256478493
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1265	14/7206	0.024190677718
ko04930	Type II diabetes mellitus	16/1265	54/7206	0.0291308587596
ko04918	Thyroid hormone synthesis	23/1265	86/7206	0.0315017850197
ko05222	Small cell lung cancer	8/1265	89/7206	0.0343704727441
ko04210	Apoptosis	21/1265	180/7206	0.0367572944136
ko04142	Lysosome	17/1265	151/7206	0.0397367571791
ko04214	Apoptosis - fly	6/1265	72/7206	0.0416261611467
ko05220	Chronic myeloid leukemia	8/1265	85/7206	0.0449808266727
ko05206	MicroRNAs in cancer	21/1265	177/7206	0.0451262379276
ko04217	Necroptosis	21/1265	178/7206	0.045363844267
ko04620	Toll-like receptor signaling pathway	10/1265	100/7206	0.046616053905
ko05320	Autoimmune thyroid disease	1/1265	29/7206	0.0478652334362
ko00562	Inositol phosphate metabolism	23/1265	89/7206	0.0484819207785
ko05416	Viral myocarditis	4/1265	55/7206	0.0485765031373
ko05200	Pathways in cancer	70/1265	492/7206	0.0492303417182