ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	154/833	423/7206	8.68643995197e-44
ko04724	Glutamatergic synapse	78/833	152/7206	2.83843305288e-34
ko05033	Nicotine addiction	45/833	56/7206	9.89808488981e-33
ko04727	GABAergic synapse	57/833	110/7206	1.55494861312e-25
ko05032	Morphine addiction	57/833	110/7206	1.55494861312e-25
ko04713	Circadian entrainment	63/833	136/7206	1.21421421644e-24
ko04728	Dopaminergic synapse	74/833	185/7206	6.85236576875e-24
ko04723	Retrograde endocannabinoid signaling	69/833	175/7206	6.61503412773e-22
ko04725	Cholinergic synapse	64/833	160/7206	8.87523584698e-21
ko04721	Synaptic vesicle cycle	42/833	80/7206	2.19888807681e-19
ko04911	Insulin secretion	48/833	117/7206	2.2193126731e-16
ko04024	cAMP signaling pathway	80/833	279/7206	2.24732537673e-15
ko04921	Oxytocin signaling pathway	63/833	209/7206	1.60497810725e-13
ko05031	Amphetamine addiction	37/833	91/7206	9.11098083529e-13
ko04726	Serotonergic synapse	47/833	137/7206	1.27019848448e-12
ko04742	Taste transduction	29/833	61/7206	2.41107880622e-12
ko04020	Calcium signaling pathway	71/833	265/7206	2.85973824221e-12
ko04720	Long-term potentiation	38/833	99/7206	3.75312121392e-12
ko04261	Adrenergic signaling in cardiomyocytes	57/833	205/7206	9.6763416023e-11
ko04744	Phototransduction	19/833	36/7206	1.62856918129e-09
ko04970	Salivary secretion	32/833	95/7206	8.7790203271e-09
ko04925	Aldosterone synthesis and secretion	33/833	105/7206	3.58868277335e-08
ko05030	Cocaine addiction	26/833	73/7206	6.0572826329e-08
ko04971	Gastric acid secretion	31/833	98/7206	7.89737648111e-08
ko04740	Olfactory transduction	27/833	80/7206	1.22652486212e-07
ko05203	Viral carcinogenesis	8/833	277/7206	1.50848969642e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	25/833	74/7206	3.52113973508e-07
ko03040	Spliceosome	1/833	145/7206	5.43846995533e-07
ko04060	Cytokine-cytokine receptor interaction	4/833	191/7206	1.6272549051e-06
ko04010	MAPK signaling pathway	66/833	321/7206	1.76062573383e-06
ko05164	Influenza A	3/833	167/7206	3.61905388402e-06
ko04514	Cell adhesion molecules (CAMs)	34/833	130/7206	4.60653554438e-06
ko04745	Phototransduction - fly	15/833	38/7206	9.19744627828e-06
ko04022	cGMP-PKG signaling pathway	47/833	216/7206	1.2233049456e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/833	79/7206	1.76074615922e-05
ko05168	Herpes simplex infection	5/833	182/7206	2.81627541767e-05
ko04730	Long-term depression	22/833	78/7206	4.58640169183e-05
ko04360	Axon guidance	48/833	233/7206	6.01408433092e-05
ko04120	Ubiquitin mediated proteolysis	3/833	138/7206	7.37836598764e-05
ko05322	Systemic lupus erythematosus	4/833	151/7206	9.34833137654e-05
ko04924	Renin secretion	23/833	86/7206	0.000101530574911
ko04972	Pancreatic secretion	27/833	111/7206	0.000130900267201
ko04072	Phospholipase D signaling pathway	41/833	197/7206	0.000156579209009
ko04260	Cardiac muscle contraction	24/833	98/7206	0.00031736242275
ko04621	NOD-like receptor signaling pathway	5/833	157/7206	0.000326998130401
ko05169	Epstein-Barr virus infection	9/833	206/7206	0.000370832874935
ko04966	Collecting duct acid secretion	10/833	26/7206	0.000377238852243
ko05162	Measles	3/833	120/7206	0.000464178410809
ko04140	Autophagy - animal	6/833	164/7206	0.000472847371108
ko03013	RNA transport	6/833	166/7206	0.000486522338516
ko05161	Hepatitis B	7/833	173/7206	0.000681135681331
ko04540	Gap junction	28/833	128/7206	0.000695690154746
ko04750	Inflammatory mediator regulation of TRP channels	27/833	122/7206	0.0008166530543
ko05414	Dilated cardiomyopathy	25/833	112/7206	0.000930767585069
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/833	182/7206	0.000941618240641
ko04141	Protein processing in endoplasmic reticulum	8/833	184/7206	0.000950529796677
ko03008	Ribosome biogenesis in eukaryotes	1/833	79/7206	0.00115217639076
ko04014	Ras signaling pathway	50/833	279/7206	0.00150313861833
ko04612	Antigen processing and presentation	1/833	77/7206	0.00177350879788
ko05205	Proteoglycans in cancer	16/833	271/7206	0.00184964020227
ko04915	Estrogen signaling pathway	27/833	131/7206	0.00224254852402
ko04070	Phosphatidylinositol signaling system	24/833	112/7206	0.00248185045621
ko04214	Apoptosis - fly	1/833	72/7206	0.00253229692585
ko04626	Plant-pathogen interaction	7/833	18/7206	0.00270985195916
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/833	14/7206	0.00309900803854
ko04976	Bile secretion	18/833	80/7206	0.00441296757061
ko04640	Hematopoietic cell lineage	1/833	64/7206	0.00552507149171
ko04064	NF-kappa B signaling pathway	3/833	96/7206	0.0056466188666
ko05215	Prostate cancer	4/833	111/7206	0.00627621379865
ko04510	Focal adhesion	15/833	240/7206	0.00729039956526
ko04110	Cell cycle	7/833	145/7206	0.00811315018641
ko04630	Jak-STAT signaling pathway	6/833	132/7206	0.0084058916221
ko05166	HTLV-I infection	20/833	292/7206	0.00864736318639
ko04210	Apoptosis	10/833	180/7206	0.00890845533661
ko04912	GnRH signaling pathway	24/833	122/7206	0.00924165217216
ko05140	Leishmaniasis	2/833	75/7206	0.0101236082819
ko01524	Platinum drug resistance	2/833	76/7206	0.0102777767524
ko05222	Small cell lung cancer	3/833	89/7206	0.0112779696125
ko04350	TGF-beta signaling pathway	4/833	103/7206	0.0118754674018
ko04150	mTOR signaling pathway	11/833	184/7206	0.0137959466087
ko05110	Vibrio cholerae infection	14/833	63/7206	0.0152223092125
ko05220	Chronic myeloid leukemia	3/833	85/7206	0.0157583346431
ko00240	Pyrimidine metabolism	5/833	110/7206	0.0157723405246
ko00480	Glutathione metabolism	1/833	55/7206	0.0178587913549
ko04668	TNF signaling pathway	6/833	120/7206	0.0204711221017
ko04114	Oocyte meiosis	25/833	139/7206	0.0221580019768
ko05034	Alcoholism	39/833	238/7206	0.0228595074062
ko04550	Signaling pathways regulating pluripotency of stem cells	10/833	165/7206	0.025688734128
ko05410	Hypertrophic cardiomyopathy (HCM)	19/833	100/7206	0.0263070832104
ko04146	Peroxisome	4/833	89/7206	0.0302103443553
ko04371	Apelin signaling pathway	30/833	177/7206	0.0311940259559
ko04916	Melanogenesis	25/833	142/7206	0.0325891452005
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/833	59/7206	0.0410530207445
ko00330	Arginine and proline metabolism	2/833	61/7206	0.042151757925
ko00310	Lysine degradation	3/833	73/7206	0.0424091765969
ko05206	MicroRNAs in cancer	12/833	177/7206	0.0427887014883
ko04330	Notch signaling pathway	2/833	62/7206	0.0429029134652
ko05202	Transcriptional misregulation in cancer	13/833	188/7206	0.0483881689281
ko04068	FoxO signaling pathway	11/833	167/7206	0.0487767045833