ko pathway ratio_in_study ratio_in_pop p_value ko04668 TNF signaling pathway 12/72 120/7206 1.72723524485e-09 ko04064 NF-kappa B signaling pathway 10/72 96/7206 2.96990106167e-08 ko04621 NOD-like receptor signaling pathway 12/72 157/7206 3.73433425442e-08 ko04060 Cytokine-cytokine receptor interaction 13/72 191/7206 3.81737321935e-08 ko04380 Osteoclast differentiation 9/72 134/7206 6.41454835096e-06 ko05321 Inflammatory bowel disease (IBD) 6/72 56/7206 1.76294204475e-05 ko04658 Th1 and Th2 cell differentiation 7/72 96/7206 4.34382714868e-05 ko05161 Hepatitis B 9/72 173/7206 4.99226766789e-05 ko05160 Hepatitis C 8/72 153/7206 0.000130204219055 ko05212 Pancreatic cancer 6/72 83/7206 0.000165749807306 ko04662 B cell receptor signaling pathway 6/72 88/7206 0.000228817490151 ko04210 Apoptosis 8/72 180/7206 0.000396610636821 ko04620 Toll-like receptor signaling pathway 6/72 100/7206 0.000458080091288 ko05152 Tuberculosis 8/72 187/7206 0.000512101390685 ko05167 Kaposi's sarcoma-associated herpesvirus infection 8/72 191/7206 0.000589499417554 ko05166 HTLV-I infection 10/72 292/7206 0.000590420175781 ko04660 T cell receptor signaling pathway 6/72 124/7206 0.00142177729701 ko01522 Endocrine resistance 6/72 124/7206 0.00142177729701 ko04657 IL-17 signaling pathway 5/72 87/7206 0.00169400482895 ko05142 Chagas disease (American trypanosomiasis) 6/72 130/7206 0.00181160681826 ko05323 Rheumatoid arthritis 5/72 89/7206 0.00187386611302 ko04217 Necroptosis 7/72 178/7206 0.00189896962994 ko04630 Jak-STAT signaling pathway 6/72 132/7206 0.00195809060299 ko04932 Non-alcoholic fatty liver disease (NAFLD) 7/72 182/7206 0.00215532422546 ko04933 AGE-RAGE signaling pathway in diabetic complications 6/72 135/7206 0.00219446239393 ko04931 Insulin resistance 6/72 137/7206 0.0023636339676 ko05146 Amoebiasis 5/72 99/7206 0.00298971723125 ko04622 RIG-I-like receptor signaling pathway 4/72 62/7206 0.00330233835199 ko04659 Th17 cell differentiation 5/72 106/7206 0.00401420629617 ko04010 MAPK signaling pathway 9/72 321/7206 0.00441927992842 ko05215 Prostate cancer 5/72 111/7206 0.00488548231195 ko04672 Intestinal immune network for IgA production 3/72 37/7206 0.00582656955988 ko04068 FoxO signaling pathway 6/72 167/7206 0.00626004229661 ko05418 Fluid shear stress and atherosclerosis 6/72 173/7206 0.00740676074694 ko04218 Cellular senescence 6/72 177/7206 0.00825140946805 ko05131 Shigellosis 4/72 82/7206 0.00891784262807 ko05200 Pathways in cancer 11/72 492/7206 0.00908752975634 ko05168 Herpes simplex infection 6/72 182/7206 0.00940247164177 ko05220 Chronic myeloid leukemia 4/72 85/7206 0.0100956640384 ko05210 Colorectal cancer 4/72 86/7206 0.0105096477168 ko04920 Adipocytokine signaling pathway 4/72 89/7206 0.01181721027 ko05219 Bladder cancer 3/72 48/7206 0.0119955201015 ko05120 Epithelial cell signaling in Helicobacter pylori infection 4/72 92/7206 0.0132252928376 ko05169 Epstein-Barr virus infection 6/72 206/7206 0.0165672229378 ko00254 Aflatoxin biosynthesis 1/72 2/7206 0.0198848865828 ko01521 EGFR tyrosine kinase inhibitor resistance 4/72 106/7206 0.021195145244 ko04071 Sphingolipid signaling pathway 5/72 162/7206 0.022551932819 ko05213 Endometrial cancer 3/72 62/7206 0.0237605156995 ko05164 Influenza A 5/72 167/7206 0.025321903336 ko05223 Non-small cell lung cancer 3/72 66/7206 0.0279512026763 ko05224 Breast cancer 5/72 174/7206 0.029555287817 ko05206 MicroRNAs in cancer 5/72 177/7206 0.0314992225304 ko01523 Antifolate resistance 2/72 30/7206 0.0357682302397 ko05145 Toxoplasmosis 4/72 126/7206 0.0368467790602 ko05134 Legionellosis 3/72 74/7206 0.0374348915588 ko04320 Dorso-ventral axis formation 2/72 31/7206 0.0379923884821 ko01524 Platinum drug resistance 3/72 76/7206 0.0400328534213 ko04072 Phospholipase D signaling pathway 5/72 197/7206 0.0465100447411 ko05230 Central carbon metabolism in cancer 3/72 81/7206 0.0469178231852