ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	163/941	423/7206	7.84143123959e-43
ko04724	Glutamatergic synapse	79/941	152/7206	2.20910795028e-31
ko05033	Nicotine addiction	43/941	56/7206	1.42266699527e-27
ko04727	GABAergic synapse	55/941	110/7206	4.48059432443e-21
ko05032	Morphine addiction	55/941	110/7206	4.48059432443e-21
ko04723	Retrograde endocannabinoid signaling	67/941	175/7206	1.42989050025e-17
ko04713	Circadian entrainment	57/941	136/7206	3.10938730603e-17
ko04728	Dopaminergic synapse	68/941	185/7206	9.88062936381e-17
ko04725	Cholinergic synapse	62/941	160/7206	1.22343387993e-16
ko04726	Serotonergic synapse	51/941	137/7206	4.33927642607e-13
ko04911	Insulin secretion	46/941	117/7206	6.35804082436e-13
ko04024	cAMP signaling pathway	78/941	279/7206	1.88679931241e-11
ko04742	Taste transduction	29/941	61/7206	5.18382497722e-11
ko04744	Phototransduction	21/941	36/7206	1.76348510246e-10
ko04721	Synaptic vesicle cycle	33/941	80/7206	2.73928684842e-10
ko04020	Calcium signaling pathway	72/941	265/7206	3.61187866628e-10
ko05031	Amphetamine addiction	35/941	91/7206	7.77717111673e-10
ko04720	Long-term potentiation	36/941	99/7206	2.69913613221e-09
ko04921	Oxytocin signaling pathway	58/941	209/7206	8.53173636899e-09
ko04925	Aldosterone synthesis and secretion	35/941	105/7206	5.89859269884e-08
ko04970	Salivary secretion	32/941	95/7206	1.6568086234e-07
ko05030	Cocaine addiction	27/941	73/7206	1.76804514957e-07
ko03040	Spliceosome	2/941	145/7206	5.94573091491e-07
ko04971	Gastric acid secretion	31/941	98/7206	1.23364463688e-06
ko04261	Adrenergic signaling in cardiomyocytes	52/941	205/7206	1.40983260608e-06
ko05322	Systemic lupus erythematosus	3/941	151/7206	2.0972536724e-06
ko04972	Pancreatic secretion	33/941	111/7206	2.82446881898e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/941	74/7206	3.50010588425e-06
ko04120	Ubiquitin mediated proteolysis	3/941	138/7206	9.79584433595e-06
ko04730	Long-term depression	24/941	78/7206	4.96754792057e-05
ko03013	RNA transport	6/941	166/7206	5.66068698571e-05
ko04010	MAPK signaling pathway	67/941	321/7206	6.13813066074e-05
ko04514	Cell adhesion molecules (CAMs)	33/941	130/7206	0.000112305679048
ko04072	Phospholipase D signaling pathway	45/941	197/7206	0.000143879005793
ko04740	Olfactory transduction	23/941	80/7206	0.000164155133411
ko04976	Bile secretion	23/941	80/7206	0.000164155133411
ko04745	Phototransduction - fly	14/941	38/7206	0.000175551397513
ko04141	Protein processing in endoplasmic reticulum	9/941	184/7206	0.000339329649715
ko04110	Cell cycle	6/941	145/7206	0.000430614475893
ko05168	Herpes simplex infection	9/941	182/7206	0.000474380406276
ko05162	Measles	4/941	120/7206	0.000512603187532
ko04014	Ras signaling pathway	57/941	279/7206	0.000520588531251
ko04750	Inflammatory mediator regulation of TRP channels	30/941	122/7206	0.000558356261906
ko04022	cGMP-PKG signaling pathway	46/941	216/7206	0.00064307399724
ko05164	Influenza A	8/941	167/7206	0.000648216299454
ko04146	Peroxisome	2/941	89/7206	0.000699380343127
ko00310	Lysine degradation	1/941	73/7206	0.000706052933624
ko05203	Viral carcinogenesis	19/941	277/7206	0.0010156902205
ko04540	Gap junction	30/941	128/7206	0.00126173879416
ko04217	Necroptosis	10/941	178/7206	0.00151073918677
ko04960	Aldosterone-regulated sodium reabsorption	13/941	41/7206	0.00153001801294
ko04964	Proximal tubule bicarbonate reclamation	10/941	29/7206	0.00263652659409
ko05016	Huntington's disease	14/941	215/7206	0.00270025384797
ko05130	Pathogenic Escherichia coli infection	2/941	77/7206	0.00321104804843
ko04612	Antigen processing and presentation	2/941	77/7206	0.00321104804843
ko00330	Arginine and proline metabolism	1/941	61/7206	0.0035014774215
ko04621	NOD-like receptor signaling pathway	9/941	157/7206	0.00382132620879
ko04360	Axon guidance	45/941	233/7206	0.00556734219282
ko04932	Non-alcoholic fatty liver disease (NAFLD)	12/941	182/7206	0.0071221711211
ko04270	Vascular smooth muscle contraction	32/941	154/7206	0.0072943270535
ko00520	Amino sugar and nucleotide sugar metabolism	1/941	55/7206	0.00775235057835
ko04915	Estrogen signaling pathway	28/941	131/7206	0.00817988631303
ko04260	Cardiac muscle contraction	22/941	98/7206	0.00947117432611
ko04710	Circadian rhythm	12/941	43/7206	0.00969903074285
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/941	59/7206	0.00989133646682
ko05166	HTLV-I infection	24/941	292/7206	0.0100581130476
ko04062	Chemokine signaling pathway	39/941	201/7206	0.0103833239581
ko03008	Ribosome biogenesis in eukaryotes	3/941	79/7206	0.0106938344247
ko05169	Epstein-Barr virus infection	15/941	206/7206	0.0113759884103
ko04966	Collecting duct acid secretion	8/941	26/7206	0.0147037424664
ko05140	Leishmaniasis	3/941	75/7206	0.0149156491234
ko04070	Phosphatidylinositol signaling system	24/941	112/7206	0.0151339442091
ko05133	Pertussis	4/941	87/7206	0.0153113847259
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/941	79/7206	0.0171027887697
ko04371	Apelin signaling pathway	34/941	177/7206	0.0175052925532
ko05231	Choline metabolism in cancer	27/941	134/7206	0.0191654718194
ko04918	Thyroid hormone synthesis	19/941	86/7206	0.0223704617211
ko04626	Plant-pathogen interaction	6/941	18/7206	0.022527091155
ko04218	Cellular senescence	13/941	177/7206	0.0231130400714
ko05414	Dilated cardiomyopathy	23/941	112/7206	0.0232281111699
ko04930	Type II diabetes mellitus	13/941	54/7206	0.0238845492141
ko05034	Alcoholism	43/941	238/7206	0.024113885356
ko04071	Sphingolipid signaling pathway	31/941	162/7206	0.0247510337752
ko03022	Basal transcription factors	1/941	44/7206	0.0247817642384
ko05144	Malaria	1/941	45/7206	0.0247982979028
ko00071	Fatty acid degradation	1/941	45/7206	0.0247982979028
ko03420	Nucleotide excision repair	1/941	46/7206	0.0252947421827
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/941	14/7206	0.0272617168042
ko02010	ABC transporters	10/941	39/7206	0.0291113211733
ko05161	Hepatitis B	13/941	173/7206	0.0292364977735
ko04630	Jak-STAT signaling pathway	9/941	132/7206	0.0356684020386
ko04924	Renin secretion	18/941	86/7206	0.0358186034217
ko05152	Tuberculosis	15/941	187/7206	0.0365479770704
ko04912	GnRH signaling pathway	24/941	122/7206	0.0405528830346
ko05416	Viral myocarditis	2/941	55/7206	0.0413787956504
ko04916	Melanogenesis	27/941	142/7206	0.0430041670394
ko01200	Carbon metabolism	9/941	128/7206	0.0457843024306
ko04658	Th1 and Th2 cell differentiation	6/941	96/7206	0.0466213033479