ko pathway ratio_in_study ratio_in_pop p_value ko04110 Cell cycle 40/297 145/7206 6.03864003549e-23 ko03440 Homologous recombination 23/297 41/7206 6.25644566442e-22 ko04111 Cell cycle - yeast 30/297 90/7206 4.89419523196e-20 ko03030 DNA replication 19/297 38/7206 4.79059419447e-17 ko03460 Fanconi anemia pathway 19/297 51/7206 4.0354242796e-14 ko00240 Pyrimidine metabolism 26/297 110/7206 1.74422039347e-13 ko04113 Meiosis - yeast 21/297 70/7206 2.53867380615e-13 ko03040 Spliceosome 29/297 145/7206 6.52278567505e-13 ko03013 RNA transport 25/297 166/7206 1.398651329e-08 ko03008 Ribosome biogenesis in eukaryotes 17/297 79/7206 1.42902374373e-08 ko03410 Base excision repair 12/297 38/7206 1.9926023641e-08 ko03430 Mismatch repair 9/297 22/7206 9.43072550576e-08 ko05322 Systemic lupus erythematosus 22/297 151/7206 1.95351924341e-07 ko04114 Oocyte meiosis 20/297 139/7206 8.76015592211e-07 ko03420 Nucleotide excision repair 11/297 46/7206 1.77864827347e-06 ko03018 RNA degradation 12/297 84/7206 0.000151523429098 ko04024 cAMP signaling pathway 1/297 279/7206 0.000159921264254 ko05205 Proteoglycans in cancer 1/297 271/7206 0.000239007803052 ko04151 PI3K-Akt signaling pathway 4/297 390/7206 0.00053584449472 ko04510 Focal adhesion 1/297 240/7206 0.000745237735749 ko03020 RNA polymerase 6/297 29/7206 0.000991671934941 ko04015 Rap1 signaling pathway 2/297 278/7206 0.00104438274474 ko04014 Ras signaling pathway 2/297 279/7206 0.00104729399388 ko04914 Progesterone-mediated oocyte maturation 12/297 104/7206 0.00111091429422 ko05034 Alcoholism 21/297 238/7206 0.00120845917994 ko04010 MAPK signaling pathway 3/297 321/7206 0.00130860411642 ko04218 Cellular senescence 17/297 177/7206 0.00148682155395 ko04810 Regulation of actin cytoskeleton 2/297 264/7206 0.00223466378257 ko05166 HTLV-I infection 23/297 292/7206 0.0024016236676 ko04022 cGMP-PKG signaling pathway 1/297 216/7206 0.00245223523708 ko00230 Purine metabolism 17/297 194/7206 0.00285247858246 ko04062 Chemokine signaling pathway 1/297 201/7206 0.00339300382225 ko04060 Cytokine-cytokine receptor interaction 1/297 191/7206 0.00493166176297 ko04072 Phospholipase D signaling pathway 1/297 197/7206 0.00521722499335 ko04530 Tight junction 2/297 228/7206 0.00624831973912 ko04360 Axon guidance 2/297 233/7206 0.00639048919667 ko05152 Tuberculosis 1/297 187/7206 0.00753565314679 ko05203 Viral carcinogenesis 21/297 277/7206 0.00770417754532 ko04115 p53 signaling pathway 8/297 74/7206 0.0107523552693 ko03015 mRNA surveillance pathway 9/297 93/7206 0.0140585402464 ko04120 Ubiquitin mediated proteolysis 12/297 138/7206 0.0141401781766 ko04722 Neurotrophin signaling pathway 1/297 160/7206 0.0149814199341 ko04071 Sphingolipid signaling pathway 1/297 162/7206 0.0150395881831 ko04140 Autophagy - animal 1/297 164/7206 0.0152050239035 ko03450 Non-homologous end-joining 3/297 15/7206 0.0218173978626 ko04932 Non-alcoholic fatty liver disease (NAFLD) 2/297 182/7206 0.0353504032474 ko04514 Cell adhesion molecules (CAMs) 1/297 130/7206 0.0448047740528 ko04630 Jak-STAT signaling pathway 1/297 132/7206 0.0448858062739 ko05231 Choline metabolism in cancer 1/297 134/7206 0.0452454513658 ko04933 AGE-RAGE signaling pathway in diabetic complications 1/297 135/7206 0.0455291518301 ko04910 Insulin signaling pathway 2/297 172/7206 0.04936458845