ko pathway ratio_in_study ratio_in_pop p_value ko04260 Cardiac muscle contraction 24/186 98/7206 1.52369660151e-17 ko05410 Hypertrophic cardiomyopathy (HCM) 24/186 100/7206 2.53224459071e-17 ko05414 Dilated cardiomyopathy 22/186 112/7206 5.23443738877e-14 ko04261 Adrenergic signaling in cardiomyocytes 26/186 205/7206 1.02328870994e-11 ko01200 Carbon metabolism 18/186 128/7206 3.61784692906e-09 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 12/186 79/7206 6.93663824149e-07 ko04510 Focal adhesion 21/186 240/7206 8.12428017304e-07 ko04974 Protein digestion and absorption 13/186 96/7206 9.19957212843e-07 ko05416 Viral myocarditis 10/186 55/7206 1.09994719666e-06 ko00020 Citrate cycle (TCA cycle) 8/186 35/7206 2.19600750169e-06 ko04020 Calcium signaling pathway 21/186 265/7206 4.04261718968e-06 ko04512 ECM-receptor interaction 11/186 79/7206 4.93808441238e-06 ko00010 Glycolysis / Gluconeogenesis 10/186 74/7206 1.76576444852e-05 ko04022 cGMP-PKG signaling pathway 17/186 216/7206 3.85480125771e-05 ko04964 Proximal tubule bicarbonate reclamation 6/186 29/7206 7.89996127895e-05 ko04921 Oxytocin signaling pathway 16/186 209/7206 9.14158582924e-05 ko00680 Methane metabolism 6/186 34/7206 0.000200907707874 ko00030 Pentose phosphate pathway 5/186 32/7206 0.00124059725173 ko01230 Biosynthesis of amino acids 8/186 85/7206 0.00149425399369 ko00710 Carbon fixation in photosynthetic organisms 4/186 27/7206 0.00473765790961 ko04922 Glucagon signaling pathway 9/186 128/7206 0.00570716869808 ko04371 Apelin signaling pathway 11/186 177/7206 0.00595566602278 ko00620 Pyruvate metabolism 5/186 46/7206 0.00631311045331 ko04152 AMPK signaling pathway 10/186 161/7206 0.00862297384241 ko05203 Viral carcinogenesis 1/186 277/7206 0.0105336033822 ko00500 Starch and sucrose metabolism 4/186 35/7206 0.0120461361494 ko00250 Alanine, aspartate and glutamate metabolism 4/186 38/7206 0.0159985995321 ko05230 Central carbon metabolism in cancer 6/186 81/7206 0.0178837982197 ko04151 PI3K-Akt signaling pathway 18/186 390/7206 0.0195645834116 ko00051 Fructose and mannose metabolism 4/186 42/7206 0.0224103254587 ko00220 Arginine biosynthesis 3/186 24/7206 0.0229890674164 ko04931 Insulin resistance 8/186 137/7206 0.0251041571983 ko04010 MAPK signaling pathway 15/186 321/7206 0.0277649253734 ko04910 Insulin signaling pathway 9/186 172/7206 0.0441931321889