ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	70/477	145/7206	6.73125089121e-45
ko04110	Cell cycle	53/477	145/7206	1.13701376659e-26
ko03030	DNA replication	25/477	38/7206	4.38326179345e-21
ko04111	Cell cycle - yeast	33/477	90/7206	5.19282885954e-17
ko03460	Fanconi anemia pathway	24/477	51/7206	1.22796359306e-15
ko03440	Homologous recombination	21/477	41/7206	8.77314084004e-15
ko03008	Ribosome biogenesis in eukaryotes	28/477	79/7206	3.54914268791e-14
ko03013	RNA transport	39/477	166/7206	1.32064175258e-12
ko00240	Pyrimidine metabolism	31/477	110/7206	1.73276991622e-12
ko03430	Mismatch repair	14/477	22/7206	5.04718891189e-12
ko03420	Nucleotide excision repair	19/477	46/7206	2.16178064405e-11
ko05322	Systemic lupus erythematosus	35/477	151/7206	2.97048732717e-11
ko04113	Meiosis - yeast	23/477	70/7206	4.3416204165e-11
ko03410	Base excision repair	17/477	38/7206	5.34548448607e-11
ko04144	Endocytosis	1/477	342/7206	1.9932386167e-09
ko05034	Alcoholism	38/477	238/7206	3.26934911396e-07
ko05203	Viral carcinogenesis	38/477	277/7206	1.80949682441e-05
ko05010	Alzheimer's disease	1/477	202/7206	2.06215464259e-05
ko03018	RNA degradation	17/477	84/7206	2.73358971851e-05
ko04024	cAMP signaling pathway	4/477	279/7206	6.31679748421e-05
ko03020	RNA polymerase	9/477	29/7206	6.85838940357e-05
ko05152	Tuberculosis	1/477	187/7206	6.86986694115e-05
ko04022	cGMP-PKG signaling pathway	2/477	216/7206	7.3434035775e-05
ko03022	Basal transcription factors	11/477	44/7206	9.87836915528e-05
ko03015	mRNA surveillance pathway	17/477	93/7206	0.000105854443986
ko04810	Regulation of actin cytoskeleton	4/477	264/7206	0.000125205730039
ko04261	Adrenergic signaling in cardiomyocytes	2/477	205/7206	0.000156431214404
ko04072	Phospholipase D signaling pathway	2/477	197/7206	0.000224729373825
ko04015	Rap1 signaling pathway	5/477	278/7206	0.000292626623379
ko04218	Cellular senescence	25/477	177/7206	0.000300731872694
ko04060	Cytokine-cytokine receptor interaction	2/477	191/7206	0.000325449804615
ko04114	Oocyte meiosis	21/477	139/7206	0.000358231954316
ko04270	Vascular smooth muscle contraction	1/477	154/7206	0.000465183421247
ko05012	Parkinson's disease	1/477	155/7206	0.000466287176409
ko04510	Focal adhesion	4/477	240/7206	0.000502296440583
ko00230	Purine metabolism	26/477	194/7206	0.000575654726357
ko05166	HTLV-I infection	35/477	292/7206	0.000643621778233
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/477	182/7206	0.000697457780491
ko04014	Ras signaling pathway	6/477	279/7206	0.00082182849659
ko04723	Retrograde endocannabinoid signaling	2/477	175/7206	0.000992348527217
ko04530	Tight junction	4/477	228/7206	0.000994341621661
ko04115	p53 signaling pathway	13/477	74/7206	0.00100041829042
ko04151	PI3K-Akt signaling pathway	11/477	390/7206	0.00105466103166
ko04010	MAPK signaling pathway	8/477	321/7206	0.00116078371839
ko04145	Phagosome	2/477	162/7206	0.00203322799499
ko05142	Chagas disease (American trypanosomiasis)	1/477	130/7206	0.00215076695756
ko04380	Osteoclast differentiation	1/477	134/7206	0.00224600369735
ko04728	Dopaminergic synapse	3/477	185/7206	0.00242816667745
ko04660	T cell receptor signaling pathway	1/477	124/7206	0.00314354124943
ko05145	Toxoplasmosis	1/477	126/7206	0.00317852444941
ko01200	Carbon metabolism	1/477	128/7206	0.00328248215226
ko04914	Progesterone-mediated oocyte maturation	15/477	104/7206	0.00407519293284
ko04724	Glutamatergic synapse	2/477	152/7206	0.00428073787614
ko04912	GnRH signaling pathway	1/477	122/7206	0.00479100486152
ko04750	Inflammatory mediator regulation of TRP channels	1/477	122/7206	0.00479100486152
ko04120	Ubiquitin mediated proteolysis	18/477	138/7206	0.00495679315564
ko05168	Herpes simplex infection	22/477	182/7206	0.00580078075171
ko04360	Axon guidance	6/477	233/7206	0.00720465280227
ko04713	Circadian entrainment	2/477	136/7206	0.00839489546571
ko04725	Cholinergic synapse	3/477	160/7206	0.00939561970217
ko04611	Platelet activation	3/477	163/7206	0.00964732917511
ko04659	Th17 cell differentiation	1/477	106/7206	0.00972892783881
ko04140	Autophagy - animal	3/477	164/7206	0.0097958036295
ko04921	Oxytocin signaling pathway	5/477	209/7206	0.0101346797234
ko05202	Transcriptional misregulation in cancer	22/477	188/7206	0.010374165708
ko05205	Proteoglycans in cancer	8/477	271/7206	0.0119617559681
ko04915	Estrogen signaling pathway	2/477	131/7206	0.0119685649188
ko04062	Chemokine signaling pathway	5/477	201/7206	0.0135305527879
ko04620	Toll-like receptor signaling pathway	1/477	100/7206	0.0141325623726
ko00564	Glycerophospholipid metabolism	1/477	99/7206	0.0141428971683
ko04066	HIF-1 signaling pathway	2/477	123/7206	0.0168545936956
ko04670	Leukocyte transendothelial migration	3/477	151/7206	0.0187549626959
ko04658	Th1 and Th2 cell differentiation	1/477	96/7206	0.0207693014359
ko04971	Gastric acid secretion	1/477	98/7206	0.0214234210657
ko05133	Pertussis	1/477	87/7206	0.0296463068697
ko04146	Peroxisome	1/477	89/7206	0.0298053990091
ko05031	Amphetamine addiction	1/477	91/7206	0.0304846072912
ko05120	Epithelial cell signaling in Helicobacter pylori infection	1/477	92/7206	0.0310193018511
ko04972	Pancreatic secretion	2/477	111/7206	0.0334535723673
ko04727	GABAergic synapse	2/477	110/7206	0.033467914184
ko05032	Morphine addiction	2/477	110/7206	0.033467914184
ko04141	Protein processing in endoplasmic reticulum	5/477	184/7206	0.0335318750668
ko05231	Choline metabolism in cancer	3/477	134/7206	0.034523421462
ko04722	Neurotrophin signaling pathway	4/477	160/7206	0.0345895412101
ko04933	AGE-RAGE signaling pathway in diabetic complications	3/477	135/7206	0.0346195528293
ko04931	Insulin resistance	3/477	137/7206	0.0350992429046
ko04726	Serotonergic synapse	3/477	137/7206	0.0350992429046
ko04910	Insulin signaling pathway	5/477	172/7206	0.0434411406572
ko01230	Biosynthesis of amino acids	1/477	85/7206	0.0440608141239
ko04371	Apelin signaling pathway	5/477	177/7206	0.0444248656123
ko04924	Renin secretion	1/477	86/7206	0.0448202449882
ko05169	Epstein-Barr virus infection	21/477	206/7206	0.0451875859445
ko05160	Hepatitis C	4/477	153/7206	0.0464596320732
ko04925	Aldosterone synthesis and secretion	2/477	105/7206	0.0469108794681
ko05222	Small cell lung cancer	11/477	89/7206	0.0481518984039
ko04012	ErbB signaling pathway	2/477	109/7206	0.0485016425556
ko04630	Jak-STAT signaling pathway	3/477	132/7206	0.0488353788825