ko pathway ratio_in_study ratio_in_pop p_value ko05200 Pathways in cancer 36/136 492/7206 5.48246784554e-13 ko05205 Proteoglycans in cancer 24/136 271/7206 1.59589781229e-10 ko05217 Basal cell carcinoma 12/136 68/7206 3.70704670181e-09 ko04390 Hippo signaling pathway 18/136 188/7206 1.1519681832e-08 ko05224 Breast cancer 15/136 174/7206 8.21983043664e-07 ko04360 Axon guidance 17/136 233/7206 1.54367540588e-06 ko04512 ECM-receptor interaction 10/136 79/7206 1.95879001047e-06 ko04510 Focal adhesion 17/136 240/7206 2.32376606668e-06 ko04550 Signaling pathways regulating pluripotency of stem cells 14/136 165/7206 2.36639484829e-06 ko04916 Melanogenesis 13/136 142/7206 2.36730921537e-06 ko05206 MicroRNAs in cancer 14/136 177/7206 5.42408140163e-06 ko05146 Amoebiasis 10/136 99/7206 1.53762106433e-05 ko04974 Protein digestion and absorption 9/136 96/7206 7.52645156166e-05 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 8/136 79/7206 0.000110682123589 ko04151 PI3K-Akt signaling pathway 19/136 390/7206 0.000120076738415 ko04310 Wnt signaling pathway 12/136 181/7206 0.000147285784618 ko05222 Small cell lung cancer 8/136 89/7206 0.000255811239334 ko05219 Bladder cancer 6/136 48/7206 0.000258890900104 ko04668 TNF signaling pathway 8/136 120/7206 0.00186694113153 ko01522 Endocrine resistance 8/136 124/7206 0.0022969480714 ko04350 TGF-beta signaling pathway 7/136 103/7206 0.00321424946172 ko04520 Adherens junction 7/136 103/7206 0.00321424946172 ko04810 Regulation of actin cytoskeleton 12/136 264/7206 0.00406028489386 ko05215 Prostate cancer 7/136 111/7206 0.00486621629292 ko04670 Leukocyte transendothelial migration 8/136 151/7206 0.00758469867265 ko05166 HTLV-I infection 12/136 292/7206 0.0123257269821 ko04933 AGE-RAGE signaling pathway in diabetic complications 7/136 135/7206 0.0136843053853 ko01521 EGFR tyrosine kinase inhibitor resistance 6/136 106/7206 0.0148019580645 ko04012 ErbB signaling pathway 6/136 109/7206 0.0167892296073 ko05212 Pancreatic cancer 5/136 83/7206 0.0199654411213 ko04320 Dorso-ventral axis formation 3/136 31/7206 0.0201001705226 ko04392 Hippo signaling pathway -multiple species 3/136 31/7206 0.0201001705226 ko04015 Rap1 signaling pathway 11/136 278/7206 0.0202215712122 ko05220 Chronic myeloid leukemia 5/136 85/7206 0.0218977046654 ko04150 mTOR signaling pathway 8/136 184/7206 0.0228116528474 ko04918 Thyroid hormone synthesis 5/136 86/7206 0.0229079344871 ko04912 GnRH signaling pathway 6/136 122/7206 0.0275304949431 ko04060 Cytokine-cytokine receptor interaction 8/136 191/7206 0.0277453372765 ko04330 Notch signaling pathway 4/136 62/7206 0.0291556542214 ko05145 Toxoplasmosis 6/136 126/7206 0.0315815149557 ko00533 Glycosaminoglycan biosynthesis - keratan sulfate 2/136 15/7206 0.0316166265848 ko04640 Hematopoietic cell lineage 4/136 64/7206 0.03227334796 ko04341 Hedgehog signaling pathway - fly 3/136 38/7206 0.0343062354194 ko04658 Th1 and Th2 cell differentiation 5/136 96/7206 0.034689880467 ko04915 Estrogen signaling pathway 6/136 131/7206 0.0371693897403 ko04144 Endocytosis 12/136 342/7206 0.0376342837147 ko05100 Bacterial invasion of epithelial cells 5/136 99/7206 0.0388394720574 ko05410 Hypertrophic cardiomyopathy (HCM) 5/136 100/7206 0.040287312648 ko04931 Insulin resistance 6/136 137/7206 0.044666856494 ko05161 Hepatitis B 7/136 173/7206 0.044919590577 ko04925 Aldosterone synthesis and secretion 5/136 105/7206 0.0480162302914 ko04218 Cellular senescence 7/136 177/7206 0.0497372807323