ko pathway ratio_in_study ratio_in_pop p_value ko04380 Osteoclast differentiation 27/197 134/7206 1.25163870859e-16 ko04621 NOD-like receptor signaling pathway 25/197 157/7206 5.40246265438e-13 ko04064 NF-kappa B signaling pathway 19/197 96/7206 7.42456795247e-12 ko04668 TNF signaling pathway 20/197 120/7206 5.59779324546e-11 ko05164 Influenza A 23/197 167/7206 1.05377939393e-10 ko04620 Toll-like receptor signaling pathway 18/197 100/7206 1.43774705897e-10 ko05161 Hepatitis B 23/197 173/7206 2.17972916146e-10 ko04060 Cytokine-cytokine receptor interaction 24/197 191/7206 2.83201344691e-10 ko04217 Necroptosis 23/197 178/7206 3.89811635617e-10 ko05167 Kaposi's sarcoma-associated herpesvirus infection 22/197 191/7206 8.65623215102e-09 ko04630 Jak-STAT signaling pathway 17/197 132/7206 9.06853775054e-08 ko05168 Herpes simplex infection 20/197 182/7206 9.51835115699e-08 ko05162 Measles 16/197 120/7206 1.35091494224e-07 ko05152 Tuberculosis 20/197 187/7206 1.49590458623e-07 ko05160 Hepatitis C 18/197 153/7206 1.52921125165e-07 ko05321 Inflammatory bowel disease (IBD) 11/197 56/7206 2.44955480186e-07 ko05145 Toxoplasmosis 15/197 126/7206 1.49203160021e-06 ko05140 Leishmaniasis 11/197 75/7206 5.11658462345e-06 ko04660 T cell receptor signaling pathway 14/197 124/7206 6.34973417488e-06 ko04933 AGE-RAGE signaling pathway in diabetic complications 14/197 135/7206 1.7086363951e-05 ko05323 Rheumatoid arthritis 11/197 89/7206 2.73110628558e-05 ko04659 Th17 cell differentiation 12/197 106/7206 2.88522537043e-05 ko04622 RIG-I-like receptor signaling pathway 9/197 62/7206 4.11287217291e-05 ko04610 Complement and coagulation cascades 10/197 79/7206 5.176543204e-05 ko04672 Intestinal immune network for IgA production 7/197 37/7206 5.26373531596e-05 ko04658 Th1 and Th2 cell differentiation 11/197 96/7206 5.58128577502e-05 ko05212 Pancreatic cancer 10/197 83/7206 7.94829738024e-05 ko04210 Apoptosis 15/197 180/7206 0.000112057188738 ko04062 Chemokine signaling pathway 16/197 201/7206 0.000113835098604 ko05133 Pertussis 10/197 87/7206 0.000118903756175 ko05144 Malaria 7/197 45/7206 0.000192800673686 ko05142 Chagas disease (American trypanosomiasis) 12/197 130/7206 0.000212883171638 ko05132 Salmonella infection 10/197 98/7206 0.00032076931747 ko05131 Shigellosis 9/197 82/7206 0.000370868528205 ko05166 HTLV-I infection 19/197 292/7206 0.000373643508121 ko04917 Prolactin signaling pathway 9/197 87/7206 0.000577145117219 ko04657 IL-17 signaling pathway 9/197 87/7206 0.000577145117219 ko04662 B cell receptor signaling pathway 9/197 88/7206 0.000627971196584 ko04623 Cytosolic DNA-sensing pathway 6/197 41/7206 0.000782982981869 ko05120 Epithelial cell signaling in Helicobacter pylori infection 9/197 92/7206 0.000869267102985 ko04650 Natural killer cell mediated cytotoxicity 9/197 97/7206 0.0012717644699 ko05150 Staphylococcus aureus infection 5/197 36/7206 0.00274570539232 ko04670 Leukocyte transendothelial migration 11/197 151/7206 0.00275131227246 ko05134 Legionellosis 7/197 74/7206 0.0039248692108 ko04932 Non-alcoholic fatty liver disease (NAFLD) 12/197 182/7206 0.00407699621789 ko05169 Epstein-Barr virus infection 13/197 206/7206 0.00412641251278 ko04080 Neuroactive ligand-receptor interaction 3/197 423/7206 0.00499054050758 ko04666 Fc gamma R-mediated phagocytosis 9/197 122/7206 0.00605151441044 ko05221 Acute myeloid leukemia 6/197 63/7206 0.00720362200875 ko05418 Fluid shear stress and atherosclerosis 11/197 173/7206 0.0076686980213 ko05340 Primary immunodeficiency 4/197 30/7206 0.00850846405986 ko05200 Pathways in cancer 23/197 492/7206 0.0096487984542 ko04624 Toll and Imd signaling pathway 5/197 49/7206 0.010437720192 ko04920 Adipocytokine signaling pathway 7/197 89/7206 0.0106751217284 ko04722 Neurotrophin signaling pathway 10/197 160/7206 0.0121097684618 ko04931 Insulin resistance 9/197 137/7206 0.012542350369 ko04930 Type II diabetes mellitus 5/197 54/7206 0.0155204878993 ko05146 Amoebiasis 7/197 99/7206 0.01838524825 ko05203 Viral carcinogenesis 14/197 277/7206 0.0229111618679 ko04068 FoxO signaling pathway 10/197 167/7206 0.0252171618699 ko05320 Autoimmune thyroid disease 3/197 29/7206 0.0436554185767 ko01523 Antifolate resistance 3/197 30/7206 0.0475606357454