ko pathway ratio_in_study ratio_in_pop p_value ko04727 GABAergic synapse 27/374 110/7206 5.70151572412e-12 ko04724 Glutamatergic synapse 31/374 152/7206 2.71384519879e-11 ko04080 Neuroactive ligand-receptor interaction 54/374 423/7206 4.10734652838e-10 ko04744 Phototransduction 14/374 36/7206 1.08071549124e-09 ko05032 Morphine addiction 24/374 110/7206 1.21428919011e-09 ko04740 Olfactory transduction 20/374 80/7206 2.43415051958e-09 ko04728 Dopaminergic synapse 29/374 185/7206 6.83058169787e-08 ko05033 Nicotine addiction 15/374 56/7206 9.31608837279e-08 ko04713 Circadian entrainment 24/374 136/7206 9.83056185584e-08 ko04726 Serotonergic synapse 23/374 137/7206 4.65141948067e-07 ko04723 Retrograde endocannabinoid signaling 25/374 175/7206 3.2837613922e-06 ko04974 Protein digestion and absorption 17/374 96/7206 7.15173247743e-06 ko04742 Taste transduction 13/374 61/7206 1.08743298825e-05 ko04725 Cholinergic synapse 22/374 160/7206 2.37979102638e-05 ko05030 Cocaine addiction 13/374 73/7206 8.10095104901e-05 ko05168 Herpes simplex infection 1/374 182/7206 0.00105960091191 ko04150 mTOR signaling pathway 1/374 184/7206 0.001074328494 ko05014 Amyotrophic lateral sclerosis (ALS) 11/374 74/7206 0.00138777143846 ko04024 cAMP signaling pathway 27/374 279/7206 0.0014334228488 ko03013 RNA transport 1/374 166/7206 0.0022602752965 ko05164 Influenza A 1/374 167/7206 0.00226669672994 ko04068 FoxO signaling pathway 1/374 167/7206 0.00226669672994 ko05031 Amphetamine addiction 12/374 91/7206 0.0024552025492 ko04721 Synaptic vesicle cycle 11/374 80/7206 0.00263352436798 ko04911 Insulin secretion 14/374 117/7206 0.0028138531965 ko04964 Proximal tubule bicarbonate reclamation 6/374 29/7206 0.00322263436726 ko04970 Salivary secretion 12/374 95/7206 0.00353068180729 ko05166 HTLV-I infection 5/374 292/7206 0.00415933314267 ko00350 Tyrosine metabolism 6/374 33/7206 0.00630787709592 ko05016 Huntington's disease 3/374 215/7206 0.00709456787535 ko05034 Alcoholism 22/374 238/7206 0.00715507509287 ko04976 Bile secretion 10/374 80/7206 0.00803479141534 ko05161 Hepatitis B 2/374 173/7206 0.00871078736559 ko00190 Oxidative phosphorylation 1/374 127/7206 0.0146646938185 ko04261 Adrenergic signaling in cardiomyocytes 19/374 205/7206 0.014929397219 ko00643 Styrene degradation 2/374 4/7206 0.0150328940213 ko04971 Gastric acid secretion 11/374 98/7206 0.0174722598037 ko05203 Viral carcinogenesis 6/374 277/7206 0.0179038569457 ko04151 PI3K-Akt signaling pathway 31/374 390/7206 0.018045973596 ko00830 Retinol metabolism 6/374 42/7206 0.0202131190038 ko04512 ECM-receptor interaction 9/374 79/7206 0.0205427940777 ko04668 TNF signaling pathway 1/374 120/7206 0.0212181998421 ko04660 T cell receptor signaling pathway 1/374 124/7206 0.0218677260555 ko05322 Systemic lupus erythematosus 2/374 151/7206 0.0246163127737 ko04514 Cell adhesion molecules (CAMs) 13/374 130/7206 0.0246195845352 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/374 182/7206 0.026052483354 ko00430 Taurine and hypotaurine metabolism 3/374 14/7206 0.0329349395995 ko04110 Cell cycle 2/374 145/7206 0.03493836436 ko04720 Long-term potentiation 10/374 99/7206 0.0369619305517 ko04540 Gap junction 12/374 128/7206 0.0417139649415 ko04745 Phototransduction - fly 5/374 38/7206 0.0449983702635 ko04020 Calcium signaling pathway 21/374 265/7206 0.0475295672876 ko04140 Autophagy - animal 3/374 164/7206 0.0486171149187 ko04931 Insulin resistance 2/374 137/7206 0.0488127633962