ko pathway ratio_in_study ratio_in_pop p_value ko04080 Neuroactive ligand-receptor interaction 32/127 423/7206 7.94743404767e-13 ko05033 Nicotine addiction 12/127 56/7206 1.53848545905e-10 ko04724 Glutamatergic synapse 17/127 152/7206 9.63856991875e-10 ko04727 GABAergic synapse 12/127 110/7206 4.33457748286e-07 ko05032 Morphine addiction 12/127 110/7206 4.33457748286e-07 ko04024 cAMP signaling pathway 18/127 279/7206 1.59462772214e-06 ko04723 Retrograde endocannabinoid signaling 14/127 175/7206 2.09309851693e-06 ko04713 Circadian entrainment 10/127 136/7206 0.000131873956125 ko04020 Calcium signaling pathway 14/127 265/7206 0.000219144164184 ko04728 Dopaminergic synapse 11/127 185/7206 0.000395670282258 ko04721 Synaptic vesicle cycle 7/127 80/7206 0.000489014502971 ko04742 Taste transduction 6/127 61/7206 0.00066884120204 ko05031 Amphetamine addiction 7/127 91/7206 0.00106193583383 ko04725 Cholinergic synapse 9/127 160/7206 0.0019846497053 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 6/127 79/7206 0.00258799718315 ko04726 Serotonergic synapse 8/127 137/7206 0.00279211557955 ko04921 Oxytocin signaling pathway 10/127 209/7206 0.00370314979472 ko04720 Long-term potentiation 6/127 99/7206 0.00784792159801 ko00515 Mannose type O-glycan biosynthesis 3/127 25/7206 0.00926342288867 ko04261 Adrenergic signaling in cardiomyocytes 9/127 205/7206 0.0100337340284 ko00510 N-Glycan biosynthesis 4/127 50/7206 0.0113400996209 ko04730 Long-term depression 5/127 78/7206 0.0119007900209 ko05414 Dilated cardiomyopathy 6/127 112/7206 0.0139375173604 ko04360 Axon guidance 9/127 233/7206 0.0215546808792 ko04072 Phospholipase D signaling pathway 8/127 197/7206 0.0227504813351 ko00604 Glycosphingolipid biosynthesis - ganglio series 2/127 14/7206 0.0244180703253 ko04915 Estrogen signaling pathway 6/127 131/7206 0.0278551452999 ko04010 MAPK signaling pathway 11/127 321/7206 0.0286559886235 ko04260 Cardiac muscle contraction 5/127 98/7206 0.0290478377232 ko05410 Hypertrophic cardiomyopathy (HCM) 5/127 100/7206 0.0313304555867 ko05014 Amyotrophic lateral sclerosis (ALS) 4/127 74/7206 0.0411340980612 ko04972 Pancreatic secretion 5/127 111/7206 0.0458765105682 ko04923 Regulation of lipolysis in adipocytes 4/127 77/7206 0.0464961555344 ko04070 Phosphatidylinositol signaling system 5/127 112/7206 0.0473689868865 ko05202 Transcriptional misregulation in cancer 7/127 188/7206 0.0479208223