ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	70/423	145/7206	1.31736194348e-48
ko03008	Ribosome biogenesis in eukaryotes	41/423	79/7206	3.30174904746e-30
ko03013	RNA transport	51/423	166/7206	3.79649190472e-24
ko03030	DNA replication	22/423	38/7206	4.45296049279e-18
ko03015	mRNA surveillance pathway	27/423	93/7206	1.34051254843e-12
ko03420	Nucleotide excision repair	18/423	46/7206	2.9436903502e-11
ko00240	Pyrimidine metabolism	27/423	110/7206	9.99131121987e-11
ko03020	RNA polymerase	14/423	29/7206	1.60978466833e-10
ko03050	Proteasome	18/423	54/7206	6.52980998718e-10
ko04110	Cell cycle	29/423	145/7206	3.63230522926e-09
ko03460	Fanconi anemia pathway	16/423	51/7206	1.60539442347e-08
ko04144	Endocytosis	1/423	342/7206	2.34652605627e-08
ko03440	Homologous recombination	14/423	41/7206	3.80869206235e-08
ko03430	Mismatch repair	10/423	22/7206	1.49475220641e-07
ko00230	Purine metabolism	30/423	194/7206	8.17644558472e-07
ko03410	Base excision repair	12/423	38/7206	9.59209703055e-07
ko04024	cAMP signaling pathway	1/423	279/7206	1.40421902602e-06
ko04810	Regulation of actin cytoskeleton	1/423	264/7206	3.02608599583e-06
ko04111	Cell cycle - yeast	17/423	90/7206	1.4827174123e-05
ko05169	Epstein-Barr virus infection	28/423	206/7206	2.7117739054e-05
ko04010	MAPK signaling pathway	4/423	321/7206	4.50788214469e-05
ko04921	Oxytocin signaling pathway	1/423	209/7206	6.97798993646e-05
ko04015	Rap1 signaling pathway	3/423	278/7206	7.21659766431e-05
ko04151	PI3K-Akt signaling pathway	7/423	390/7206	9.0604448575e-05
ko03018	RNA degradation	15/423	84/7206	9.26532009033e-05
ko05010	Alzheimer's disease	1/423	202/7206	0.000102802603428
ko04510	Focal adhesion	2/423	240/7206	0.000114282582772
ko04072	Phospholipase D signaling pathway	1/423	197/7206	0.000154397572357
ko00970	Aminoacyl-tRNA biosynthesis	10/423	44/7206	0.000178270544183
ko04728	Dopaminergic synapse	1/423	185/7206	0.000343392519868
ko04723	Retrograde endocannabinoid signaling	1/423	175/7206	0.00048246021669
ko05205	Proteoglycans in cancer	4/423	271/7206	0.0005150505238
ko04113	Meiosis - yeast	12/423	70/7206	0.000678811657003
ko04062	Chemokine signaling pathway	2/423	201/7206	0.000698794280004
ko04725	Cholinergic synapse	1/423	160/7206	0.00103340220071
ko04611	Platelet activation	1/423	163/7206	0.00105282479094
ko05168	Herpes simplex infection	22/423	182/7206	0.0011136136301
ko05012	Parkinson's disease	1/423	155/7206	0.0015219903507
ko04621	NOD-like receptor signaling pathway	1/423	157/7206	0.00155786800204
ko04014	Ras signaling pathway	5/423	279/7206	0.00157049053198
ko05200	Pathways in cancer	14/423	492/7206	0.00193771163168
ko04623	Cytosolic DNA-sensing pathway	8/423	41/7206	0.0022691606966
ko04142	Lysosome	1/423	151/7206	0.00230712451033
ko04670	Leukocyte transendothelial migration	1/423	151/7206	0.00230712451033
ko04724	Glutamatergic synapse	1/423	152/7206	0.00235554552099
ko04371	Apelin signaling pathway	2/423	177/7206	0.00301885963985
ko04916	Melanogenesis	1/423	142/7206	0.00326276775329
ko04933	AGE-RAGE signaling pathway in diabetic complications	1/423	135/7206	0.00474648610881
ko04713	Circadian entrainment	1/423	136/7206	0.00479683058537
ko04726	Serotonergic synapse	1/423	137/7206	0.00486685589009
ko04712	Circadian rhythm - plant	3/423	7/7206	0.00588535488836
ko04071	Sphingolipid signaling pathway	2/423	162/7206	0.00607558923704
ko04145	Phagosome	2/423	162/7206	0.00607558923704
ko04390	Hippo signaling pathway	3/423	188/7206	0.00687793141468
ko04630	Jak-STAT signaling pathway	1/423	132/7206	0.00732999144787
ko05160	Hepatitis C	2/423	153/7206	0.00856966942935
ko03060	Protein export	5/423	23/7206	0.00949941826263
ko03450	Non-homologous end-joining	4/423	15/7206	0.00951768411131
ko04932	Non-alcoholic fatty liver disease (NAFLD)	3/423	182/7206	0.00965891943159
ko04360	Axon guidance	5/423	233/7206	0.0100958626285
ko03022	Basal transcription factors	7/423	44/7206	0.013259622991
ko04910	Insulin signaling pathway	3/423	172/7206	0.0132880859449
ko04530	Tight junction	5/423	228/7206	0.0138700660545
ko04217	Necroptosis	3/423	178/7206	0.0138935120097
ko04550	Signaling pathways regulating pluripotency of stem cells	3/423	165/7206	0.0184206150183
ko04139	Mitophagy - yeast	6/423	37/7206	0.0194804590073
ko04727	GABAergic synapse	1/423	110/7206	0.0216480873801
ko05032	Morphine addiction	1/423	110/7206	0.0216480873801
ko04972	Pancreatic secretion	1/423	111/7206	0.0220264729846
ko05034	Alcoholism	6/423	238/7206	0.0236698291564
ko05231	Choline metabolism in cancer	2/423	134/7206	0.0243465770396
ko04931	Insulin resistance	2/423	137/7206	0.0250860722629
ko04722	Neurotrophin signaling pathway	3/423	160/7206	0.0255952017156
ko05152	Tuberculosis	4/423	187/7206	0.0257622577616
ko04140	Autophagy - animal	3/423	164/7206	0.0265935629949
ko04720	Long-term potentiation	1/423	99/7206	0.0301624117855
ko04922	Glucagon signaling pathway	2/423	128/7206	0.0344434986624
ko04540	Gap junction	2/423	128/7206	0.0344434986624
ko05418	Fluid shear stress and atherosclerosis	4/423	173/7206	0.0471797891373
ko04919	Thyroid hormone signaling pathway	3/423	143/7206	0.047981904496
ko04666	Fc gamma R-mediated phagocytosis	2/423	122/7206	0.048660219586