ko pathway ratio_in_study ratio_in_pop p_value ko04380 Osteoclast differentiation 20/169 134/7206 2.64757287434e-11 ko04064 NF-kappa B signaling pathway 13/169 96/7206 3.04653544251e-07 ko04060 Cytokine-cytokine receptor interaction 18/169 191/7206 4.35650787136e-07 ko04621 NOD-like receptor signaling pathway 15/169 157/7206 3.54148936518e-06 ko04668 TNF signaling pathway 13/169 120/7206 4.05544093447e-06 ko05150 Staphylococcus aureus infection 7/169 36/7206 1.62098640511e-05 ko05168 Herpes simplex infection 15/169 182/7206 2.15183343727e-05 ko04660 T cell receptor signaling pathway 12/169 124/7206 3.05744609868e-05 ko05164 Influenza A 14/169 167/7206 3.38391545824e-05 ko04662 B cell receptor signaling pathway 10/169 88/7206 3.59347083521e-05 ko04658 Th1 and Th2 cell differentiation 10/169 96/7206 7.64178102877e-05 ko05162 Measles 11/169 120/7206 0.000108374992997 ko04611 Platelet activation 13/169 163/7206 0.00010874327962 ko04666 Fc gamma R-mediated phagocytosis 11/169 122/7206 0.000125829375055 ko05167 Kaposi's sarcoma-associated herpesvirus infection 14/169 191/7206 0.000146181218653 ko05161 Hepatitis B 13/169 173/7206 0.000198108565265 ko04630 Jak-STAT signaling pathway 11/169 132/7206 0.000253514445449 ko05140 Leishmaniasis 8/169 75/7206 0.000343493548376 ko04610 Complement and coagulation cascades 8/169 79/7206 0.000490614584102 ko05340 Primary immunodeficiency 5/169 30/7206 0.000592339914604 ko04659 Th17 cell differentiation 9/169 106/7206 0.000811200280665 ko05160 Hepatitis C 11/169 153/7206 0.000893764190785 ko04217 Necroptosis 12/169 178/7206 0.000928386642934 ko04210 Apoptosis 12/169 180/7206 0.0010238708986 ko04672 Intestinal immune network for IgA production 5/169 37/7206 0.00158723678991 ko04650 Natural killer cell mediated cytotoxicity 8/169 97/7206 0.00190275205084 ko04664 Fc epsilon RI signaling pathway 7/169 77/7206 0.00208560901231 ko04623 Cytosolic DNA-sensing pathway 5/169 41/7206 0.00253057493268 ko04622 RIG-I-like receptor signaling pathway 6/169 62/7206 0.0031586478864 ko04657 IL-17 signaling pathway 7/169 87/7206 0.00416925298774 ko05133 Pertussis 7/169 87/7206 0.00416925298774 ko05152 Tuberculosis 11/169 187/7206 0.00438663391376 ko04145 Phagosome 10/169 162/7206 0.0046503942041 ko05323 Rheumatoid arthritis 7/169 89/7206 0.00472838882459 ko04620 Toll-like receptor signaling pathway 7/169 100/7206 0.00887053851273 ko04612 Antigen processing and presentation 6/169 77/7206 0.0091393741954 ko05166 HTLV-I infection 14/169 292/7206 0.00933415540135 ko05145 Toxoplasmosis 8/169 126/7206 0.00934060876093 ko05321 Inflammatory bowel disease (IBD) 5/169 56/7206 0.00973583662237 ko04921 Oxytocin signaling pathway 11/169 209/7206 0.00990162152449 ko05131 Shigellosis 6/169 82/7206 0.0122699796598 ko04917 Prolactin signaling pathway 6/169 87/7206 0.0160888219688 ko05330 Allograft rejection 3/169 24/7206 0.0178632924601 ko04010 MAPK signaling pathway 14/169 321/7206 0.0220312370895 ko04670 Leukocyte transendothelial migration 8/169 151/7206 0.0253275413347 ko05132 Salmonella infection 6/169 98/7206 0.0272238251915 ko05320 Autoimmune thyroid disease 3/169 29/7206 0.0296238735989 ko05169 Epstein-Barr virus infection 10/169 206/7206 0.0297737041099 ko05416 Viral myocarditis 4/169 55/7206 0.0394618186107 ko04144 Endocytosis 14/169 342/7206 0.0409662144069