ko pathway ratio_in_study ratio_in_pop p_value ko04070 Phosphatidylinositol signaling system 19/412 112/7206 1.62116195528e-05 ko04710 Circadian rhythm 11/412 43/7206 2.03400811997e-05 ko04960 Aldosterone-regulated sodium reabsorption 10/412 41/7206 7.5634620361e-05 ko04020 Calcium signaling pathway 31/412 265/7206 0.000120293827294 ko04724 Glutamatergic synapse 21/412 152/7206 0.000137242746076 ko04964 Proximal tubule bicarbonate reclamation 7/412 29/7206 0.000987169003694 ko04919 Thyroid hormone signaling pathway 18/412 143/7206 0.00145259359853 ko04014 Ras signaling pathway 29/412 279/7206 0.00146577743356 ko05322 Systemic lupus erythematosus 1/412 151/7206 0.0022241182655 ko03040 Spliceosome 1/412 145/7206 0.00325935828188 ko04110 Cell cycle 1/412 145/7206 0.00325935828188 ko04744 Phototransduction 7/412 36/7206 0.00373512680326 ko04080 Neuroactive ligand-receptor interaction 38/412 423/7206 0.00478302874927 ko04072 Phospholipase D signaling pathway 21/412 197/7206 0.00481904200078 ko04711 Circadian rhythm - fly 4/412 13/7206 0.00498050855989 ko04745 Phototransduction - fly 7/412 38/7206 0.00511740636865 ko04725 Cholinergic synapse 18/412 160/7206 0.00516337755088 ko05031 Amphetamine addiction 12/412 91/7206 0.00537808877117 ko05230 Central carbon metabolism in cancer 11/412 81/7206 0.00605135500882 ko03013 RNA transport 2/412 166/7206 0.00608853467232 ko03010 Ribosome 1/412 129/7206 0.00687768323641 ko04713 Circadian entrainment 16/412 136/7206 0.00744351707396 ko04726 Serotonergic synapse 16/412 137/7206 0.00763181734043 ko04925 Aldosterone synthesis and secretion 13/412 105/7206 0.00856408191642 ko04360 Axon guidance 23/412 233/7206 0.00924001712012 ko04024 cAMP signaling pathway 26/412 279/7206 0.0120666169712 ko05223 Non-small cell lung cancer 9/412 66/7206 0.0121802879423 ko04971 Gastric acid secretion 12/412 98/7206 0.0126670410036 ko03320 PPAR signaling pathway 9/412 69/7206 0.016052877098 ko00562 Inositol phosphate metabolism 11/412 89/7206 0.0172546580114 ko00471 D-Glutamine and D-glutamate metabolism 2/412 4/7206 0.0181153755096 ko04911 Insulin secretion 13/412 117/7206 0.0236732802351 ko04720 Long-term potentiation 11/412 99/7206 0.028041916291 ko04066 HIF-1 signaling pathway 13/412 123/7206 0.0287754506178 ko00051 Fructose and mannose metabolism 6/412 42/7206 0.0307828680404 ko04973 Carbohydrate digestion and absorption 6/412 42/7206 0.0307828680404 ko00565 Ether lipid metabolism 6/412 42/7206 0.0307828680404 ko04727 GABAergic synapse 12/412 110/7206 0.034075427614 ko05032 Morphine addiction 12/412 110/7206 0.034075427614 ko05203 Viral carcinogenesis 8/412 277/7206 0.0345592853266 ko04141 Protein processing in endoplasmic reticulum 4/412 184/7206 0.0348470599998 ko00350 Tyrosine metabolism 5/412 33/7206 0.0376968700289 ko05033 Nicotine addiction 7/412 56/7206 0.0391404349102 ko00604 Glycosphingolipid biosynthesis - ganglio series 3/412 14/7206 0.0421644974659 ko04976 Bile secretion 9/412 80/7206 0.0467995458564