ko pathway ratio_in_study ratio_in_pop p_value ko03440 Homologous recombination 18/324 41/7206 2.79256680084e-14 ko04110 Cell cycle 29/324 145/7206 5.91905142615e-12 ko03460 Fanconi anemia pathway 16/324 51/7206 3.31037453163e-10 ko04111 Cell cycle - yeast 19/324 90/7206 1.17040524184e-08 ko04080 Neuroactive ligand-receptor interaction 1/324 423/7206 8.07266790988e-08 ko03040 Spliceosome 21/324 145/7206 1.72793453352e-06 ko03008 Ribosome biogenesis in eukaryotes 15/324 79/7206 1.76590103646e-06 ko03410 Base excision repair 9/324 38/7206 3.44734973532e-05 ko04113 Meiosis - yeast 12/324 70/7206 5.63454183003e-05 ko03013 RNA transport 19/324 166/7206 0.000153247089047 ko03030 DNA replication 8/324 38/7206 0.000229406629624 ko03018 RNA degradation 12/324 84/7206 0.000339946699673 ko00240 Pyrimidine metabolism 14/324 110/7206 0.000381559796795 ko05166 HTLV-I infection 27/324 292/7206 0.000398402505125 ko05206 MicroRNAs in cancer 18/324 177/7206 0.00122149517677 ko04218 Cellular senescence 18/324 177/7206 0.00122149517677 ko04330 Notch signaling pathway 9/324 62/7206 0.00165830205404 ko04060 Cytokine-cytokine receptor interaction 1/324 191/7206 0.00230032757771 ko04020 Calcium signaling pathway 3/324 265/7206 0.00361641448683 ko03420 Nucleotide excision repair 7/324 46/7206 0.00410546106828 ko00310 Lysine degradation 9/324 73/7206 0.00515131578244 ko04139 Mitophagy - yeast 6/324 37/7206 0.0056320866514 ko04115 p53 signaling pathway 9/324 74/7206 0.00563933633022 ko04022 cGMP-PKG signaling pathway 2/324 216/7206 0.00653615763461 ko04152 AMPK signaling pathway 1/324 161/7206 0.0106224070613 ko04550 Signaling pathways regulating pluripotency of stem cells 15/324 165/7206 0.0113115832269 ko03430 Mismatch repair 4/324 22/7206 0.0154392832318 ko04151 PI3K-Akt signaling pathway 8/324 390/7206 0.0160238819112 ko04510 Focal adhesion 4/324 240/7206 0.0259105297423 ko04914 Progesterone-mediated oocyte maturation 10/324 104/7206 0.0261737993911 ko03450 Non-homologous end-joining 3/324 15/7206 0.0274021271279 ko01200 Carbon metabolism 1/324 128/7206 0.0309936229962 ko05215 Prostate cancer 10/324 111/7206 0.0330150351415 ko04145 Phagosome 2/324 162/7206 0.0347935155829 ko05034 Alcoholism 4/324 238/7206 0.036283783638 ko05010 Alzheimer's disease 3/324 202/7206 0.0363921852196 ko03015 mRNA surveillance pathway 9/324 93/7206 0.0368961174618 ko04919 Thyroid hormone signaling pathway 12/324 143/7206 0.0372809782726 ko03020 RNA polymerase 4/324 29/7206 0.0392393965162 ko04144 Endocytosis 8/324 342/7206 0.044954046226 ko00190 Oxidative phosphorylation 1/324 127/7206 0.0468422636556 ko04122 Sulfur relay system 2/324 8/7206 0.0471523768754 ko05012 Parkinson's disease 2/324 155/7206 0.0486482400412